Related papers: Clusters in Explanation Space: Inferring disease s…
Cluster analysis methods are used to identify homogeneous subgroups in a data set. In biomedical applications, one frequently applies cluster analysis in order to identify biologically interesting subgroups. In particular, one may wish to…
We present a clustering-based explainability technique for digital pathology models based on convolutional neural networks. Unlike commonly used methods based on saliency maps, such as occlusion, GradCAM, or relevance propagation, which…
We present a pipeline in which unsupervised machine learning techniques are used to automatically identify subtypes of hospital patients admitted between 2017 and 2021 in a large UK teaching hospital. With the use of state-of-the-art…
Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…
Cancer is a number of related yet highly heterogeneous diseases. Correct identification of cancer subtypes is critical for clinical decisions. The advance in sequencing technologies has made it possible to study cancer based on abundant…
A recent trend in machine learning has been to enrich learned models with the ability to explain their own predictions. The emerging field of Explainable AI (XAI) has so far mainly focused on supervised learning, in particular, deep neural…
Clustering is a fundamental learning task widely used as a first step in data analysis. For example, biologists use cluster assignments to analyze genome sequences, medical records, or images. Since downstream analysis is typically…
Recent work on explainable clustering allows describing clusters when the features are interpretable. However, much modern machine learning focuses on complex data such as images, text, and graphs where deep learning is used but the raw…
Clustering is an unsupervised learning problem that aims to partition unlabelled data points into groups with similar features. Traditional clustering algorithms provide limited insight into the groups they find as their main focus is…
We introduce the Neural Collaborative Subspace Clustering, a neural model that discovers clusters of data points drawn from a union of low-dimensional subspaces. In contrast to previous attempts, our model runs without the aid of spectral…
Detecting latent structure within a dataset is a crucial step in performing analysis of a dataset. However, existing state-of-the-art techniques for subclass discovery are limited: either they are limited to detecting very small numbers of…
Model explainability is essential for the creation of trustworthy Machine Learning models in healthcare. An ideal explanation resembles the decision-making process of a domain expert and is expressed using concepts or terminology that is…
Extracting an understanding of the underlying system from high dimensional data is a growing problem in science. Discovering informative and meaningful features is crucial for clustering, classification, and low dimensional data embedding.…
In digital pathology, both detection and classification of cells are important for automatic diagnostic and prognostic tasks. Classifying cells into subtypes, such as tumor cells, lymphocytes or stromal cells is particularly challenging.…
Clustering algorithms rely on complex optimisation processes that may be difficult to comprehend, especially for individuals who lack technical expertise. While many explainable artificial intelligence techniques exist for supervised…
This study focuses on exploring the use of local interpretability methods for explaining time series clustering models. Many of the state-of-the-art clustering models are not directly explainable. To provide explanations for these…
The domain of explainable AI is of interest in all Machine Learning fields, and it is all the more important in clustering, an unsupervised task whose result must be validated by a domain expert. We aim at finding a clustering that has high…
In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…
In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…
Many of the kinds of language model used in speech understanding suffer from imperfect modeling of intra-sentential contextual influences. I argue that this problem can be addressed by clustering the sentences in a training corpus…