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Due to large number of entities in biomedical knowledge bases, only a small fraction of entities have corresponding labelled training data. This necessitates entity linking models which are able to link mentions of unseen entities using…

Computation and Language · Computer Science 2021-04-12 Rico Angell , Nicholas Monath , Sunil Mohan , Nishant Yadav , Andrew McCallum

Subspace clustering is an unsupervised clustering technique designed to cluster data that is supported on a union of linear subspaces, with each subspace defining a cluster with dimension lower than the ambient space. Many existing…

Machine Learning · Computer Science 2021-03-23 Benjamin D. Haeffele , Chong You , René Vidal

We discuss topological aspects of cluster analysis and show that inferring the topological structure of a dataset before clustering it can considerably enhance cluster detection: theoretical arguments and empirical evidence show that…

Machine Learning · Computer Science 2022-07-04 Moritz Herrmann , Daniyal Kazempour , Fabian Scheipl , Peer Kröger

Explaining deep learning models is essential for clinical integration of medical image analysis systems. A good explanation highlights if a model depends on spurious features that undermines generalization and harms a subset of patients or,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Yoni Schirris , Eric Marcus , Jonas Teuwen , Hugo Horlings , Efstratios Gavves

Subspace clustering algorithms are used for understanding the cluster structure that explains the dataset well. These methods are extensively used for data-exploration tasks in various areas of Natural Sciences. However, most of these…

Machine Learning · Computer Science 2022-11-15 Ashutosh Singh , Ashish Singh , Aria Masoomi , Tales Imbiriba , Erik Learned-Miller , Deniz Erdogmus

Not long ago primary census data became available to publicity. It opened qualitatively new perspectives not only for researchers in demography and sociology, but also for those people, who somehow face processes occurring in society. In…

Databases · Computer Science 2011-06-28 Oleg Chertov , Marharyta Aleksandrova

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

Multiple types or views of data (e.g. genetics, proteomics) measured on the same set of individuals are now popularly generated in many biomedical studies. A particular interest might be the detection of sample subgroups (e.g. subtypes of…

Methodology · Statistics 2025-05-09 Kaifeng Yang , Thierry Chekouo , Sandra E. Safo

We consider the problem of image classification for the purpose of aiding doctors in dermatological diagnosis. Dermatological diagnosis poses two major challenges for standard off-the-shelf techniques: First, the data distribution is…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Viraj Prabhu , Anitha Kannan , Murali Ravuri , Manish Chablani , David Sontag , Xavier Amatriain

Causal structure learning refers to a process of identifying causal structures from observational data, and it can have multiple applications in biomedicine and health care. This paper provides a practical review and tutorial on scalable…

Machine Learning · Computer Science 2023-01-20 Pulakesh Upadhyaya , Kai Zhang , Can Li , Xiaoqian Jiang , Yejin Kim

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

Recent years have seen an increased focus into the tasks of predicting hospital inpatient risk of deterioration and trajectory evolution due to the availability of electronic patient data. A common approach to these problems involves…

Machine Learning · Computer Science 2020-11-18 Henrique Aguiar , Mauro Santos , Peter Watkinson , Tingting Zhu

Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…

Machine Learning · Statistics 2023-10-20 Dimitrios Saligkaras , Vasileios E. Papageorgiou

Clustering multimorbidity has been a global research priority in recent years. Existing studies usually identify these clusters using one of several popular clustering methods and then explore various characteristics of these clusters,…

Applications · Statistics 2025-05-06 Sohan Seth , Nazir Lone , Niels Peek , Bruce Guthrie

Accurate and interpretable diagnostic models are crucial in the safety-critical field of medicine. We investigate the interpretability of our proposed biomarker-based lung ultrasound diagnostic pipeline to enhance clinicians' diagnostic…

In this paper, we introduce a novel and interpretable methodology to cluster subjects suffering from cancer, based on features extracted from their biopsies. Contrary to existing approaches, we propose here to capture complex patterns in…

Quantitative Methods · Quantitative Biology 2020-07-07 Yassine El Ouahidi , Matis Feller , Matthieu Talagas , Bastien Pasdeloup

In mission-critical domains such as law enforcement and medical diagnosis, the ability to explain and interpret the outputs of deep learning models is crucial for ensuring user trust and supporting informed decision-making. Despite…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Bharat Chandra Yalavarthi , Nalini Ratha

Cancer is a leading cause of death in many countries. An early diagnosis of cancer based on biomedical imaging ensures effective treatment and a better prognosis. However, biomedical imaging presents challenges to both clinical institutions…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Hosein Barzekar , Yash Patel , Ling Tong , Zeyun Yu

To make sense of massive data, we often fit simplified models and then interpret the parameters; for example, we cluster the text embeddings and then interpret the mean parameters of each cluster. However, these parameters are often…

Artificial Intelligence · Computer Science 2025-01-14 Ruiqi Zhong , Heng Wang , Dan Klein , Jacob Steinhardt

It has been hypothesized that some form of "modular" structure in artificial neural networks should be useful for learning, compositionality, and generalization. However, defining and quantifying modularity remains an open problem. We cast…

Machine Learning · Computer Science 2022-06-23 Richard D. Lange , David S. Rolnick , Konrad P. Kording