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We develop a scalable multi-step Monte Carlo algorithm for inference under a large class of nonparametric Bayesian models for clustering and classification. Each step is "embarrassingly parallel" and can be implemented using the same Markov…

Computation · Statistics 2018-06-08 Yang Ni , Peter Müller , Maurice Diesendruck , Sinead Williamson , Yitan Zhu , Yuan Ji

The discovery of disease subtypes is an essential step for developing precision medicine, and disease subtyping via omics data has become a popular approach. While promising, subtypes obtained from conventional approaches may not be…

Applications · Statistics 2023-09-28 Lingsong Meng , Zhiguang Huo

Background: Single-cell RNA sequencing (scRNA-seq) is a powerful profiling technique at the single-cell resolution. Appropriate analysis of scRNA-seq data can characterize molecular heterogeneity and shed light into the underlying cellular…

Applications · Statistics 2019-08-05 Siamak Zamani Dadaneh , Paul de Figueiredo , Sing-Hoi Sze , Mingyuan Zhou , Xiaoning Qian

We propose a self-supervised Gaussian ATtention network for image Clustering (GATCluster). Rather than extracting intermediate features first and then performing the traditional clustering algorithm, GATCluster directly outputs semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Chuang Niu , Jun Zhang , Ge Wang , Jimin Liang

We present the use of single-cell entropy (scEntropy) to measure the order of the cellular transcriptome profile from single-cell RNA-seq data, which leads to a method of unsupervised cell type classification through scEntropy followed by…

Quantitative Methods · Quantitative Biology 2020-02-18 Jingxin Liu , You Song , Jinzhi Lei

Microbiome research has immense potential for unlocking insights into human health and disease. A common goal in human microbiome research is identifying subgroups of individuals with similar microbial composition that may be linked to…

Methodology · Statistics 2025-08-21 Suppapat Korsurat , Matthew D. Koslovsky

Image clustering, which involves grouping images into different clusters without labels, is a key task in unsupervised learning. Although previous deep clustering methods have achieved remarkable results, they only explore the intrinsic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Haixin Zhang , Yongjun Li , Dong Huang

Subspace clustering is the classical problem of clustering a collection of data samples that approximately lie around several low-dimensional subspaces. The current state-of-the-art approaches for this problem are based on the…

Machine Learning · Computer Science 2023-01-26 Maryam Abdolali , Nicolas Gillis

Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering…

Quantitative Methods · Quantitative Biology 2023-01-11 Nana Wei , Yating Nie , Lin Liu , Xiaoqi Zheng , Hua-Jun Wu4

Cell type identification from single-cell transcriptomic data is a common goal of single-cell RNA sequencing (scRNAseq) data analysis. Neural networks have been employed to identify cell types from scRNAseq data with high performance.…

Genomics · Quantitative Biology 2020-05-11 Xishuang Dong , Shanta Chowdhury , Uboho Victor , Xiangfang Li , Lijun Qian

Sparse Subspace Clustering (SSC) has achieved state-of-the-art clustering quality by performing spectral clustering over a $\ell^{1}$-norm based similarity graph. However, SSC is a transductive method which does not handle with the data not…

Machine Learning · Computer Science 2014-09-11 Xi Peng , Lei Zhang , Zhang Yi

Two successful approaches for the segmentation of biomedical images are (1) the selection of segment candidates from a merge-tree, and (2) the clustering of small superpixels by solving a Multi-Cut problem. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Jan Funke , Chong Zhang , Tobias Pietzsch , Stephan Saalfeld

In this paper, we propose an extension for semi-supervised Minimum Sum-of-Squares Clustering (MSSC) problems of MDEClust, a memetic framework based on the Differential Evolution paradigm for unsupervised clustering. In semi-supervised MSSC,…

Optimization and Control · Mathematics 2025-12-02 Pierluigi Mansueto , Fabio Schoen

This paper studies the large-scale subspace clustering (LSSC) problem with million data points. Many popular subspace clustering methods cannot directly handle the LSSC problem although they have been considered as state-of-the-art methods…

Machine Learning · Computer Science 2020-04-10 Jun Li , Hongfu Liu , Zhiqiang Tao , Handong Zhao , Yun Fu

We propose a novel approach to the problem of multilevel clustering, which aims to simultaneously partition data in each group and discover grouping patterns among groups in a potentially large hierarchically structured corpus of data. Our…

Machine Learning · Statistics 2017-06-14 Nhat Ho , XuanLong Nguyen , Mikhail Yurochkin , Hung Hai Bui , Viet Huynh , Dinh Phung

Spectral clustering is a celebrated algorithm that partitions objects based on pairwise similarity information. While this approach has been successfully applied to a variety of domains, it comes with limitations. The reason is that there…

Statistics Theory · Mathematics 2018-05-24 Kwangjun Ahn , Kangwook Lee , Changho Suh

Clustering is one of the most widely used procedures in the analysis of microarray data, for example with the goal of discovering cancer subtypes based on observed heterogeneity of genetic marks between different tissues. It is well-known…

Methodology · Statistics 2009-04-21 Heng Lian

As single-cell gene expression data analysis continues to grow, the need for reliable clustering methods has become increasingly important. The prevalence of heuristic means for method choice could lead to inaccurate reports if…

Quantitative Methods · Quantitative Biology 2026-05-19 Owen Visser , Somnath Datta

Subspace clustering (SC) refers to the problem of clustering high-dimensional data into a union of low-dimensional subspaces. Based on spectral clustering, state-of-the-art approaches solve SC problem within a two-stage framework. In the…

Machine Learning · Computer Science 2019-05-06 Shuai Yang , Wenqi Zhu , Yuesheng Zhu

Sparse subspace clustering (SSC) is one of the current state-of-the-art methods for partitioning data points into the union of subspaces, with strong theoretical guarantees. However, it is not practical for large data sets as it requires…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Maryam Abdolali , Nicolas Gillis , Mohammad Rahmati