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This paper proposes an adaptive neuro-fuzzy framework to improve drug infusion rate in closed-loop control of anesthesia. The proposed controller provides a sub-optimal propofol administration rate as input to reach the desired bispectral…

Systems and Control · Electrical Eng. & Systems 2019-10-16 Mohammad Javad Khodaei , Mohammad Hadi Balaghi Inaloo , Amin Mehrvarz , Nader Jalili

Left ventricular assist devices (LVADs) can provide mechanical support for a failing heart as bridge to transplant and destination therapy. Physiological control systems for LVADs should be designed to respond to changes in hemodynamic…

Systems and Control · Electrical Eng. & Systems 2020-02-14 Masoud Fetanat , Michael Stevens , Christopher Hayward , Nigel Hamilton Lovell

In chemical process applications, model predictive control effectively deals with input and state constraints during transient operations. However, industrial PID controllers directly manipulates the actuators, so they play the key role in…

Systems and Control · Computer Science 2013-05-29 Minh Hoang-Tuan Nguyen , Kok Kiong Tan

In this paper, an efficient control strategy for physiological interaction based anaesthetic drug infusion model is explored using the fractional order (FO) proportional integral derivative (PID) controllers. The dynamic model is composed…

Systems and Control · Computer Science 2016-12-01 Saptarshi Das , Sourav Das , Koushik Maharatna

This paper presents the design and robustness analysis of fractional and integer order PID controllers for the control of a non-linear industrial process in the presence of parametric uncertainness and external disturbances. The nonlinear…

Systems and Control · Computer Science 2018-10-31 J. Viola , L. Angel

Precise control of lower limb exoskeletons during sit-to-stand (STS) transitions remains a central challenge in rehabilitation robotics owing to the highly nonlinear, time-varying dynamics of the human-exoskeleton system and the stringent…

Robotics · Computer Science 2026-04-07 Ranjeet Kumbhar , Rajmeet Singh , Appaso M Gadade , Ashish Singla , Irfan Hussain

This study investigates the performance of cascade PID control architecture applied to an inverted pendulum on a cart system through both simulation and experimental implementation. A nonlinear model of the system was developed using…

Systems and Control · Electrical Eng. & Systems 2026-05-11 Khalid Mehrab , Md Zamiul Alam , Shadman Tahmid Haque

The continuous and discrete time Linear Quadratic Regulator (LQR) theory has been used in this paper for the design of optimal analog and discrete PID controllers respectively. The PID controller gains are formulated as the optimal…

Optimization and Control · Mathematics 2013-01-18 Saptarshi Das , Indranil Pan , Kaushik Halder , Shantanu Das , Amitava Gupta

This paper investigates the control of nonlinear systems using a piecewise linear approximation framework. The proposed approach combines a PID controller with locally linearized models obtained by partitioning the nonlinear function into…

Optimization and Control · Mathematics 2026-04-14 Robert Vrabel

The purpose of this paper is to present a theoretic and numerical study of utilizing squeezing and phase shift in coherent feedback control of linear quantum optical systems. A quadrature representation with built-in phase shifters is…

Quantum Physics · Physics 2012-06-19 Guofeng Zhang , Heung Wing Joseph Lee , Bo Huang , Hu Zhang

Significant effort toward the automation of general anesthesia has been made in the past decade. One open challenge is in the development of control-ready patient models for closed-loop anesthesia delivery. Standard depth-of-anesthesia…

Neurons and Cognition · Quantitative Biology 2019-12-18 John H. Abel , Marcus A. Badgeley , Taylor E. Baum , Sourish Chakravarty , Patrick L. Purdon , Emery N. Brown

The PID controller parameters can be adjusted in such a manner that it gives the desired frequency response and the results are found using the Bodes integral formula in order to adjust the slope of the nyquist curve in a desired manner.…

Systems and Control · Computer Science 2013-01-01 Anish Acharya , Debatri Mitra , Kaushik Halder

Since the classical proportional-integral-derivative (PID) controller has continued to be the most widely used feedback methods in engineering systems by far, it is crucial to investigate the working mechanism of PID in dealing with…

Optimization and Control · Mathematics 2025-12-03 Baoyou Qu , Cheng Zhao

This paper studies a class of partially observed Linear Quadratic Gaussian (LQG) problems with unknown dynamics. We establish an end-to-end sample complexity bound on learning a robust LQG controller for open-loop stable plants. This is…

Optimization and Control · Mathematics 2021-07-14 Yang Zheng , Luca Furieri , Maryam Kamgarpour , Na Li

We compare the performance of proportional-integral-derivative (PID) control, linear model predictive control (LMPC), and nonlinear model predictive control (NMPC) for a physical setup of the quadruple tank system (QTS). We estimate the…

Systems and Control · Electrical Eng. & Systems 2022-12-12 Anders H. D. Andersen , Tobias K. S. Ritschel , Steen Hørsholt , Jakob Kjøbsted Huusom , John Bagterp Jørgensen

This paper presents a comparative study of three advanced control strategies for a single-machine infinite-bus (SMIB) system: the nonlinear feedback linearizing controller (NFLC), the integral-NFLC (INFLC), and the…

Systems and Control · Electrical Eng. & Systems 2025-02-18 Pratik Vernekar

Left ventricular assist devices (LVADs) are mechanical pumps, which can be used to support heart failure (HF) patients as bridge to transplant and destination therapy. To automatically adjust the LVAD speed, a physiological control system…

Systems and Control · Electrical Eng. & Systems 2021-05-04 Masoud Fetanat , Michael Stevens , Christopher Hayward , Nigel H. Lovell

Motivated by recent advances of reinforcement learning and direct data-driven control, we propose policy gradient adaptive control (PGAC) for the linear quadratic regulator (LQR), which uses online closed-loop data to improve the control…

Optimization and Control · Mathematics 2025-06-16 Feiran Zhao , Alessandro Chiuso , Florian Dörfler

PID control has been the dominant control strategy in the process industry due to its simplicity in design and effectiveness in controlling a wide range of processes. However, traditional methods on PID tuning often require extensive domain…

Systems and Control · Electrical Eng. & Systems 2022-02-14 Ayub I. Lakhani , Myisha A. Chowdhury , Qiugang Lu

Medical drug infusion problems pose a combination of challenges such as nonlinearities from physiological models, model uncertainty due to inter- and intra-patient variability, as well as strict safety specifications. With these challenges…

Systems and Control · Electrical Eng. & Systems 2023-01-24 Sophie Hall , Lukas Ortmann , Miguel Picallo , Florian Dörfler
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