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Microfluidic biochips are replacing the conventional biochemical analysers integrating the necessary functions on-chip. We are interested in Flow-Based Microfluidic Biochips (FBMB), where a continuous flow of liquid is manipulated using…

Emerging Technologies · Computer Science 2025-05-07 Alexander Schneider , Jan Madsen , Paul Pop

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

Arrays of H-shape microfluidic channels connecting two different fluidic reservoirs have been built with silicon/SU8 microfabrication technologies utilized in production of thermal inkjet printheads. The fluids are delivered to the channels…

Fluid Dynamics · Physics 2018-02-13 Brandon S. Hayes , Alexander N. Govyadinov , Pavel E. Kornilovitch

Advances in flexible catheters pave the way for minimally invasive diagnosis and treatment of luminal organs and tubular structures through endoluminal interventions. A key challenge is in establishing non-constraining pressure monitoring…

Medical Physics · Physics 2025-11-04 Xiaotong Guo , Qindong Zheng , Jinshi Zhao , Bing Li , Eric Morgan Yeatman

Abstract: In our paper the new algorithm enhanced multi gradient Dilution Preparation (EMDP) is discussed. This new algorithm is reported with a lab on chip or digital Microfluidic biochip to operate multiple operation on a tiny chip. We…

Emerging Technologies · Computer Science 2021-10-04 Meenakshi Sanyal , Somenath Chakraborty

Controlling fluid droplets efficiently in the microscale is of great interest both from a basic science and a technology perspective. We have designed and developed a general-purpose, highly scalable microfluidic control strategy through a…

Fluid Dynamics · Physics 2013-10-15 Georgios Katsikis , Manu Prakash

A robust route for the biased production of single-handed chiral structures has been found in generating non-spherical, multi-component double emulsions using microfluidics. The specific type of handedness is determined by the final packing…

Soft Condensed Matter · Physics 2018-04-20 Laura L. A. Adams , Samuel A. Ocko

Droplet-based microfluidics turned out to be an efficient and adjustable platform for digital analysis, encapsulation of cells, drug formulation, and polymerase chain reaction. Typically, for most biomedical applications, the handling of…

Soft Condensed Matter · Physics 2018-01-30 Enrico Chiarello , Anupam Gupta , Giampaolo Mistura , Mauro Sbragaglia , Matteo Pierno

Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…

Medical Physics · Physics 2019-02-07 S. Harput , L. Nie , D. M. J. Cowell , T. Carpenter , B. Raiton , J. McLaughlan , S. Freear

High throughput screening of small molecules and natural products is costly, requiring significant amounts of time, reagents, and operating space. Although microarrays have proven effective in the miniaturization of screening for certain…

Biomolecules · Quantitative Biology 2022-10-17 Tracey N. Bell , Aubrey E. Kusi-Appiaha , Pengfei Lyu , L. Zhu , F. Zhu , David Van Winkle , Hongyuan Cao , M. Singh , Steven Lenhert

We present a mesoscale representation of near-contact interactions between colliding droplets which permits to reach up to the scale of full microfluidic devices, where such droplets are produced. The method is demonstrated for the case of…

Computational Physics · Physics 2020-06-23 Andrea Montessori , Marco Lauricella , Adriano Tiribocchi , Sauro Succi

Microfluidic systems hold great potential for the study of live microscopic cultures of cells, tissue samples, and small organisms. Integration of hyperpolarisation would enable quantitative studies of metabolism in such volume limited…

Fine manipulation of fluid flows at the microscale has a tremendous impact on mass transport phenomena of chemical and biological processes inside microfluidic platforms. Fluid mixing in the laminar flow regime at low Reynolds is poorly…

The rheology of pressure-driven flows of two-dimensional dense monodisperse emulsions in neutral wetting microchannels is investigated by means of mesoscopic lattice simulations, capable of handling large collections of droplets, in the…

Soft Condensed Matter · Physics 2019-12-03 Linlin Fei , Andrea Scagliarini , Kai H. Luo , Sauro Succi

Fluorosurfactant-stabilized microdroplets hold significant promise for a wide range of applications, owing to their biological and chemical inertness. However, conventional synthetic routes for fluorosurfactants typically require multiple…

Microfluidics and lab-on-a-chip technologies have made it possible to manipulate small volume liquids with unprecedented resolution, automation and integration. However, most current microfluidic systems still rely on bulky off-chip…

Instrumentation and Detectors · Physics 2014-05-22 Baichen Li , Lin Li , Allan Guan , Quan Dong , Kangcheng Ruan , Ronggui Hu , Zhenyu Li

The development of microfluidic devices is still hindered by the lack of robust fundamental building blocks that constitute any fluidic system. An attractive approach is optical actuation because light field interaction is contactless and…

Novel microstamping tool for microarray printing is proposed. The tool is capable to spot up to 127 droplets of different solutions in single touch. It is easily compatible with commercially available microarray spotters. The tool is based…

Medical Physics · Physics 2009-01-22 Alexei L Drobyshev , Nikolai N Verkhodanov , Alexander S Zasedatelev

Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…

Soft Condensed Matter · Physics 2019-06-21 Laura Andreina Chacon Orellana , Jean-Christophe Baret

We report an easy-to-implement method that allows the direct generation of water-in-water (w/w) single emulsions. The method relies on direct perturbation of the pressure that drives the flow of the dispersed phase of the emulsions. The…

Fluid Dynamics · Physics 2012-12-06 Alban Sauret , Ho Cheung Shum