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This is an early but comprehensive review of the PNP Poisson Nernst Planck theory of ion channels. Extensive reference is made to the earlier literature. The starting place for this theory of open channels is a theory of electrodiffusion…

Biomolecules · Quantitative Biology 2010-09-16 Bob Eisenberg

The phase offset between surface charge modulation and geometric undulations in a corrugated nanochannel provides a tunable mechanism for rectified, diode-like ion transport under purely pressure-driven conditions: reversing the applied…

Fluid Dynamics · Physics 2026-05-15 Thomas Petersen , Pouya Golchin , Jinwoo Im , Felipe P. J. de Barros

A discrete rate theory for general multi-ion channels is presented, in which the continuous dynamics of ion diffusion is reduced to transitions between Markovian discrete states. In an open channel, the ion permeation process involves three…

Biological Physics · Physics 2012-06-29 Wan Chen , Radek Erban , S. Jonathan Chapman

We revisit the classical problem of diffusion-limited ion transport to a membrane (or electrode) by considering the effects of charged side walls. Using simple mathematical models and numerical simulations, we identify three basic…

Fluid Dynamics · Physics 2015-05-30 E. Victoria Dydek , Boris Zaltzman , Isaak Rubinstein , D. S. Deng , Ali Mani , Martin Z. Bazant

Dynamic conductivity of the one-dimensional ion conductor is investigated at different values of the interaction constant between particles and the modulating field. The consideration is based on the hard-core boson lattice model.…

Strongly Correlated Electrons · Physics 2017-02-13 I. V. Stasyuk , R. Ya. Stetsiv

Diffusion is a fundamental physical phenomenon with critical applications in fields such as metallurgy, cell biology, and population dynamics. While standard diffusion is well-understood, anomalous diffusion often requires complex non-local…

Statistical Mechanics · Physics 2026-01-16 Gabriel Barreiro , Vladimir Pérez-Veloz

Electrostatic interaction between ions in an ionic channel and the charge fluctuations in the channel mouth are considered. It is shown that the charge fluctuations can be enhanced in the channels with low dielectric constant and result in…

Biological Physics · Physics 2007-05-23 D. G. Luchinsky , R. Tindjong , I. Kaufman , P. V. E. McClintock , R. S. Eisenberg

Diffusion and reaction of initially separated ions A- and B+ in the presence of counter ions A'+ and B'- is studied. The dynamics is described in terms of reaction-diffusion equations obeying local electroneutrality, and the time-evolution…

Statistical Mechanics · Physics 2009-10-31 T. Unger , Z. Racz

Translocation properties of ionic channels are investigated, on the basis of classical electrostatics, with an emphasis on asymptotic formulas for the potential and field associated with a point charge in the channel. Due to image charges…

Soft Condensed Matter · Physics 2007-05-23 Sofian Teber

A modified Poisson-Nernst-Planck system in a bounded domain with mixed Dirichlet-Neumann boundary conditions is analyzed. It describes the concentrations of ions immersed in a polar solvent and the correlated electric potential due to the…

Analysis of PDEs · Mathematics 2023-05-25 Ansgar Jüngel , Annamaria Massimini

In this article we address the three-dimensional modeling and simulation of biological ion channels using a continuum-based approach. Our multi-physics formulation self-consistently combines, to the best of our knowledge for the first time,…

Numerical Analysis · Mathematics 2015-09-25 Riccardo Sacco , Paolo Airoldi , Aurelio G. Mauri , Joseph W. Jerome

We investigate the subtle effects of diffuse charge on interfacial kinetics by solving the governing equations for ion transport (Nernst-Planck) with realistic boundary conditions representing reaction kinetics (Butler-Volmer) and…

Soft Condensed Matter · Physics 2007-05-23 A. Bonnefont , F. Argoul , M. Z. Bazant

We investigate the diffusiophoresis of a non-polarizable droplet laden with soluble ionic surfactant, for which the surface charge arises from adsorption of surfactant at the fluid-fluid interface. Unlike previous studies that assume either…

Fluid Dynamics · Physics 2026-02-09 Subrata Majhi , Somnath Bhattacharyya

The standard model of enhanced ionic conductivities in solid electrolyte heterostructures follows from a continuum mean-field description of defect distributions that makes no reference to crystalline structure. To examine ionic transport…

Materials Science · Physics 2015-06-18 Benjamin J. Morgan , Paul A. Madden

Ion-conducting glasses and polymer systems show several characteristic peculiarities in their composition-dependent diffusion properties and in their dynamic response. First we give a brief review of the current understanding of the ion…

Condensed Matter · Physics 2016-08-31 O. Durr , P. Pendzig , W. Dieterich , A. Nitzan

Systematic and careful studies are made on the properties of the IJ=00 $\pi\pi$ and $K\bar K$ coupled-channel system, using newly derived dispersion relations between the phase shifts and poles and cuts. The effects of nearby branch point…

High Energy Physics - Phenomenology · Physics 2009-03-19 Zhiguang Xiao , Hanqing Zheng

This paper is devoted to the study of some nonlinear parabolic equations with discontinuous diffusion intensities. Such problems appear naturally in physical and biological models. Our analysis is based on variational techniques and in…

Analysis of PDEs · Mathematics 2021-02-09 Dohyun Kwon , Alpár Richárd Mészáros

We combine quantum-chemical calculations and molecular dynamics simulations to consider aqueous ion flow across non-axisymmetric nanopores in monolayer graphene and MoS$_2$. When the pore-containing membrane is subject to uniaxial tensile…

Applied Physics · Physics 2020-04-30 A. Smolyanitsky , A. Fang , A. F. Kazakov , E. Paulechka

In charged nanopores, ionic diffusion current reflects the ionic selectivity and ionic permeability of nanopores which determines the performance of osmotic energy conversion, i.e. the output power and efficiency. Here, theoretical…

Chemical Physics · Physics 2023-09-15 Long Ma , Zihao Gao , Jia Man , Jianyong Li , Guanghua Du , Yinghua Qiu

The transmembrane voltage, $V$, which is the potential drop required to nullify the electrical current ($i=0$), is a key characteristic of water desalination and energy harvesting systems that utilize macroscopically large nanoporous…

Mesoscale and Nanoscale Physics · Physics 2026-04-28 Ramadan Abu-Rjal , Yoav Green