Related papers: Multiscale Mechanical Behavior of Large Arteries
Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive…
Predicting the structural response of advanced multiphase alloys and understanding the underlying microscopic mechanisms that are responsible for it are two critically important roles modeling plays in alloy development. An alloys…
It has been shown that geometrical, structural properties vary along the length of the aortic arch. There is a scarcity of studies focus on the variation in the vessel wall thickness of aortic arch. The central premise of this study is that…
State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…
Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some…
When stressed sufficiently, solid materials yield and deform plastically via reorganization of microscopic constituents. Indeed, it is possible to alter the micro-structure of materials by judicious application of stress, an empirical pro-…
Synchronization of activity among myocytes constituting vital organs, e.g., the heart, is crucial for physiological functions. Self-organized coordination in such heterogeneous ensemble of excitable and oscillatory cells is therefore of…
Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…
The biomechanical properties of blood clots, which are dictated by their compositions and micro-structures, play a critical role in determining their fates, occlusion, persistency, or embolization in the human circulatory system. While…
Healthy cartilage is a remarkable tissue, able to withstand tens of millions of loading cycles with minimal damage. While much is known about the structural origins of its compressive mechanics, how composition determines its mechanical…
The motility of a cell can be triggered or inhibited not only by an applied force but also by a mechanically neutral force couple. This type of loading, represented by an applied stress and commonly interpreted as either squeezing or…
The mechanical properties of a material are intimately related to its microstructure. This is particularly important for predicting mechanical behavior of polycrystalline metals, where microstructural variations dictate the expected…
Nematic elastomers are rubbery solids which have liquid crystals incorporated into their polymer chains. These materials display many unusual mechanical properties, one such being the ability to form fine-scale microstructure. In this work,…
The role of mechanics is known to be of primary order in many arterial diseases; however, determining mechanical properties of arteries remains a challenge. This paper discusses the identifiability of the passive mechanical properties of a…
Many emerging applications in microscale engineering rely on the fabrication of three-dimensional architectures in inorganic materials. Small-scale additive manufacturing (AM) aspires to provide flexible and facile access to these…
Cartilage is a connective tissue that covers the surfaces of bones in joints and provides a smooth gliding surface for movement. It is characterized by specific biophysical properties that allow it to withstand compressive loads, distribute…
Arterial biomechanical indicators have long been recognized as fundamental contributors to the physiology and pathology of cardiovascular systems. Probing the multiple biomechanical parameters of arteries simultaneously at different time…
Bacterial colonies growing on surfaces are shaped by mechanical stresses transmitted through the community, governed by the balance between cell growth and steric and cell-substrate interactions. Using overdamped dynamics simulations of…
This paper presents an analytical study about the behavior of arbitrary shaped and sized non-cohesive two-dimensional granular materials. Several mechanical properties and relations are unraveled by connecting micro and macro scales in an…
Active arterial mechanics, governed by vascular smooth muscle contraction, are critical to physiological regulation, cardiovascular disease progression, and clinical diagnosis. Although various in vivo methods have been developed to assess…