English
Related papers

Related papers: Pre-Training of Deep Bidirectional Protein Sequenc…

200 papers

Protein language models have excelled in a variety of tasks, ranging from structure prediction to protein engineering. However, proteins are highly diverse in functions and structures, and current state-of-the-art models including the…

Biomolecules · Quantitative Biology 2023-02-27 Chang Ma , Haiteng Zhao , Lin Zheng , Jiayi Xin , Qintong Li , Lijun Wu , Zhihong Deng , Yang Lu , Qi Liu , Lingpeng Kong

Deep neural networks have gained tremendous success in a broad range of machine learning tasks due to its remarkable capability to learn semantic-rich features from high-dimensional data. However, they often require large-scale labelled…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Hu Wang , Guansong Pang , Chunhua Shen , Congbo Ma

Currently, under supervised learning, a model pretrained by a large-scale nature scene dataset and then fine-tuned on a few specific task labeling data is the paradigm that has dominated the knowledge transfer learning. It has reached the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-15 Tong Zhang , Peng Gao , Hao Dong , Yin Zhuang , Guanqun Wang , Wei Zhang , He Chen

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Recently, there has been great interest in learning how to best represent proteins, specifically with fixed-length embeddings. Deep learning has become a popular tool for protein representation learning as a model's hidden layers produce…

Biomolecules · Quantitative Biology 2020-11-09 Amir Shanehsazzadeh , David Belanger , David Dohan

Semi-supervised learning has the potential to improve the data-efficiency of training data-hungry deep neural networks, which is especially important for medical image analysis tasks where labeled data is scarce. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Boon Peng Yap , Beng Koon Ng

Inferring the structural properties of a protein from its amino acid sequence is a challenging yet important problem in biology. Structures are not known for the vast majority of protein sequences, but structure is critical for…

Machine Learning · Computer Science 2019-10-17 Tristan Bepler , Bonnie Berger

We consider a multilingual weakly supervised learning scenario where knowledge from annotated corpora in a resource-rich language is transferred via bitext to guide the learning in other languages. Past approaches project labels across…

Computation and Language · Computer Science 2013-10-08 Mengqiu Wang , Christopher D. Manning

Semi-supervised learning is a model training method that uses both labeled and unlabeled data. This paper proposes a fully Bayes semi-supervised learning algorithm that can be applied to any multi-category classification problem. We assume…

Machine Learning · Statistics 2024-07-22 Rui Zhu , Shuvrarghya Ghosh , Subhashis Ghosal

Recent developments in Natural Language Processing (NLP) demonstrate that large-scale, self-supervised pre-training can be extremely beneficial for downstream tasks. These ideas have been adapted to other domains, including the analysis of…

Computation and Language · Computer Science 2021-02-02 Matthew B. A. McDermott , Brendan Yap , Harry Hsu , Di Jin , Peter Szolovits

Deep neural networks (DNNs) have been employed for designing wireless systems in many aspects, say transceiver design, resource optimization, and information prediction. Existing works either use the fully-connected DNN or the DNNs with…

Machine Learning · Computer Science 2020-01-31 Jia Guo , Chenyang Yang

Predicting phenotypes from gene expression data is a crucial task in biomedical research, enabling insights into disease mechanisms, drug responses, and personalized medicine. Traditional machine learning and deep learning rely on…

Machine Learning · Computer Science 2025-09-18 Kevin Dradjat , Massinissa Hamidi , Pierre Bartet , Blaise Hanczar

The success of supervised deep learning models on cell recognition tasks relies on detailed annotations. Many previous works have managed to reduce the dependency on labels. However, considering the large number of cells contained in a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Pingyi Chen , Chenglu Zhu , Zhongyi Shui , Jiatong Cai , Sunyi Zheng , Shichuan Zhang , Lin Yang

Coarse-grained linguistic information, such as named entities or phrases, facilitates adequately representation learning in pre-training. Previous works mainly focus on extending the objective of BERT's Masked Language Modeling (MLM) from…

Computation and Language · Computer Science 2021-04-14 Dongling Xiao , Yu-Kun Li , Han Zhang , Yu Sun , Hao Tian , Hua Wu , Haifeng Wang

We propose to pre-train a unified language model for both autoencoding and partially autoregressive language modeling tasks using a novel training procedure, referred to as a pseudo-masked language model (PMLM). Given an input text with…

Computation and Language · Computer Science 2020-03-02 Hangbo Bao , Li Dong , Furu Wei , Wenhui Wang , Nan Yang , Xiaodong Liu , Yu Wang , Songhao Piao , Jianfeng Gao , Ming Zhou , Hsiao-Wuen Hon

Effective convolutional neural networks are trained on large sets of labeled data. However, creating large labeled datasets is a very costly and time-consuming task. Semi-supervised learning uses unlabeled data to train a model with higher…

Computer Vision and Pattern Recognition · Computer Science 2016-06-16 Mehdi Sajjadi , Mehran Javanmardi , Tolga Tasdizen

Due to abundance of data from multiple modalities, cross-modal retrieval tasks with image-text, audio-image, etc. are gaining increasing importance. Of the different approaches proposed, supervised methods usually give significant…

Computer Vision and Pattern Recognition · Computer Science 2020-01-03 Devraj Mandal , Pramod Rao , Soma Biswas

Semi-supervised learning is a challenging problem which aims to construct a model by learning from limited labeled examples. Numerous methods for this task focus on utilizing the predictions of unlabeled instances consistency alone to…

Computer Vision and Pattern Recognition · Computer Science 2021-12-30 Peng Tu , Yawen Huang , Feng Zheng , Zhenyu He , Liujun Cao , Ling Shao

Language models (LMs) trained on vast quantities of unlabelled data have greatly advanced the field of natural language processing (NLP). In this study, we re-visit the widely accepted notion in NLP that continued pre-training LMs on…

Computation and Language · Computer Science 2023-10-09 Zhengxiang Shi , Aldo Lipani

A successful paradigm in representation learning is to perform self-supervised pretraining using tasks based on mini-batch statistics (e.g., SimCLR, VICReg, SwAV, MSN). We show that in the formulation of all these methods is an overlooked…