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Unsupervised pretraining, which learns a useful representation using a large amount of unlabeled data to facilitate the learning of downstream tasks, is a critical component of modern large-scale machine learning systems. Despite its…

Machine Learning · Statistics 2023-03-06 Jiawei Ge , Shange Tang , Jianqing Fan , Chi Jin

The capability of accurate prediction of protein functions and properties is essential in the biotechnology industry, e.g. drug development and artificial protein synthesis, etc. The main challenges of protein function prediction are the…

Quantitative Methods · Quantitative Biology 2021-12-02 Wei-Cheng Tseng , Po-Han Chi , Jia-Hua Wu , Min Sun

Inspired by recent findings on the fractal geometry of language, we introduce Recursive INference Scaling (RINS) as a complementary, plug-in recipe for scaling inference time in language and multimodal systems. RINS is a particular form of…

Artificial Intelligence · Computer Science 2025-05-09 Ibrahim Alabdulmohsin , Xiaohua Zhai

In this study, we tackle the challenging task of predicting secondary structures from protein primary sequences, a pivotal initial stride towards predicting tertiary structures, while yielding crucial insights into protein activity,…

Machine Learning · Computer Science 2025-11-18 Disha Varshney , Samarth Garg , Sarthak Tyagi , Deeksha Varshney , Nayan Deep , Asif Ekbal

Recently, prompt tuning \cite{lester2021power} has gradually become a new paradigm for NLP, which only depends on the representation of the words by freezing the parameters of pre-trained language models (PLMs) to obtain remarkable…

Computation and Language · Computer Science 2022-01-31 Pan He , Yuxi Chen , Yan Wang , Yanru Zhang

Fine-tuning a pre-trained language model via the contrastive learning framework with a large amount of unlabeled sentences or labeled sentence pairs is a common way to obtain high-quality sentence representations. Although the contrastive…

Computation and Language · Computer Science 2022-11-01 Tianduo Wang , Wei Lu

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

State-of-the-art deep learning approaches for skin lesion recognition often require pretraining on larger and more varied datasets, to overcome the generalization limitations derived from the reduced size of the skin lesion imaging…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Kirill Sirotkin , Marcos Escudero-Viñolo , Pablo Carballeira , Juan Carlos SanMiguel

Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

Machine Learning · Computer Science 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

With the success of large-scale pre-training in language tasks, there is an increasing trend of applying it to the domain of life sciences. In particular, pre-training methods based on DNA sequences have received increasing attention…

Artificial Intelligence · Computer Science 2024-09-10 Chaoqi Liang , Lifeng Qiao , Peng Ye , Nanqing Dong , Jianle Sun , Weiqiang Bai , Yuchen Ren , Xinzhu Ma , Hongliang Yan , Chunfeng Song , Wanli Ouyang , Wangmeng Zuo

The goal of semi-supervised learning is to utilize the unlabeled, in-domain dataset U to improve models trained on the labeled dataset D. Under the context of large-scale language-model (LM) pretraining, how we can make the best use of U is…

Computation and Language · Computer Science 2020-11-20 Zijun Sun , Chun Fan , Xiaofei Sun , Yuxian Meng , Fei Wu , Jiwei Li

Protein language models often take into consideration the alignment between a protein sequence and its textual description. However, they do not take structural information into consideration. Traditional methods treat sequence and…

Machine Learning · Computer Science 2026-03-10 Aditya Ranganath , Hasin Us Sami , Kowshik Thopalli , Bhavya Kailkhura , Wesam Sakla

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

Pre-trained vision-language models learn massive data to model unified representations of images and natural languages, which can be widely applied to downstream machine learning tasks. In addition to zero-shot inference, in order to better…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Qian-Wei Wang , Yuqiu Xie , Letian Zhang , Zimo Liu , Shu-Tao Xia

Learning from large amounts of unsupervised data and a small amount of supervision is an important open problem in computer vision. We propose a new semi-supervised learning method, Semantic Positives via Pseudo-Labels (SemPPL), that…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Matko Bošnjak , Pierre H. Richemond , Nenad Tomasev , Florian Strub , Jacob C. Walker , Felix Hill , Lars Holger Buesing , Razvan Pascanu , Charles Blundell , Jovana Mitrovic

Recent years have witnessed the success of heterogeneous graph neural networks (HGNNs) in modeling heterogeneous information networks (HINs). In this paper, we focus on the benchmark task of HGNNs, i.e., node classification, and empirically…

Social and Information Networks · Computer Science 2023-04-04 Cheng Yang , Xumeng Gong , Chuan Shi , Philip S. Yu

This work proposes a hybrid unsupervised and supervised learning method to pre-train models applied in Earth observation downstream tasks when only a handful of labels denoting very general semantic concepts are available. We combine a…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Omar A. Castaño-Idarraga , Raul Ramos-Pollán , Freddie Kalaitzis

Existing RNN-based approaches for action recognition from depth sequences require either skeleton joints or hand-crafted depth features as inputs. An end-to-end manner, mapping from raw depth maps to action classes, is non-trivial to design…

Computer Vision and Pattern Recognition · Computer Science 2017-08-09 Zhiyuan Shi , Tae-Kyun Kim

In recent years, self-supervised learning has attracted widespread academic debate and addressed many of the key issues of computer vision. The present research focus is on how to construct a good agent task that allows for improved network…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Zhijie Xiao , Zhicheng Dong , Hao Xiang

We present a neural semi-supervised learning model termed Self-Pretraining. Our model is inspired by the classic self-training algorithm. However, as opposed to self-training, Self-Pretraining is threshold-free, it can potentially update…

Computation and Language · Computer Science 2021-10-01 Payam Karisani , Negin Karisani
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