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Related papers: Pinning Stabilizer Design for Large-Scale Probabil…

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Boolean networks (BNs) are discrete-time systems where nodes are inter-connected (here we call such connection rule among nodes as network structure), and the dynamics of each gene node is determined by logical functions. In this paper, we…

Systems and Control · Electrical Eng. & Systems 2020-11-03 Jie Zhong , Daniel W. C. Ho , Jianquan Lu

In this article, we design the distributed pinning controllers to globally stabilize a Boolean network (BN), specially a sparsely connected large-scale one, towards a preassigned subset of state space through the node-to-node message…

Systems and Control · Electrical Eng. & Systems 2022-03-16 Shiyong Zhu , Jianquan Lu , Liangjie Sun , Jinde Cao

This paper focuses on proposing a general control framework for large-scale Boolean networks (\texttt{BNs}). Only by the network structure, the concept of structural controllability for \texttt{BNs} is formalized. A necessary and sufficient…

Systems and Control · Electrical Eng. & Systems 2021-05-27 Shiyong Zhu , Jianquan Lu , Shun-ichi Azuma , Wei Xing Zheng

The area of Smart Power Grids needs to constantly improve its efficiency and resilience, to pro-vide high quality electrical power, in a resistant grid, managing faults and avoiding failures. Achieving this requires high component…

Machine Learning · Computer Science 2021-02-03 Pedro J. Rivera Torres , Carlos Gershenson García , Samir Kanaan Izquierdo

A probabilistic Boolean network (PBN) is a discrete-time system composed of a collection of Boolean networks between which the PBN switches in a stochastic manner. This paper focuses on the study of quotients of PBNs. Given a PBN and an…

Optimization and Control · Mathematics 2021-08-02 Rui Li , Qi Zhang , Tianguang Chu

Probabilistic Boolean Networks (PBNs) were introduced as a computational model for the study of complex dynamical systems, such as Gene Regulatory Networks (GRNs). Controllability in this context is the process of making strategic…

Machine Learning · Computer Science 2020-09-08 Georgios Papagiannis , Sotiris Moschoyiannis

Probabilistic Boolean networks (PBNs) is an important mathematical framework widely used for modelling and analysing biological systems. PBNs are suited for modelling large biological systems, which more and more often arise in systems…

Computational Engineering, Finance, and Science · Computer Science 2016-05-04 Andrzej Mizera , Jun Pang , Qixia Yuan

Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…

Molecular Networks · Quantitative Biology 2015-05-13 Andrew Pomerance , Edward Ott , Michelle Girvan , Wolfgang Losert

In this paper, a set of sensors is constructed via the pinning observability approach with the help of observability criteria given in [1] and [2], in order to make the given Boolean network (BN) be observable. Given the assumption that…

Systems and Control · Electrical Eng. & Systems 2022-03-08 Shiyong Zhu , Jianquan Lu , Jie Zhong , Yang Liu , Jinde Cao

The ability to direct a Probabilistic Boolean Network (PBN) to a desired state is important to applications such as targeted therapeutics in cancer biology. Reinforcement Learning (RL) has been proposed as a framework that solves a…

Machine Learning · Computer Science 2022-10-26 Sotiris Moschoyiannis , Evangelos Chatzaroulas , Vytenis Sliogeris , Yuhu Wu

Probabilistic Boolean Networks have been proposed for estimating the behaviour of dynamical systems as they combine rule-based modelling with uncertainty principles. Inferring PBNs directly from gene data is challenging however, especially…

Systems and Control · Electrical Eng. & Systems 2022-11-14 Vytenis Šliogeris , Leandros Maglaras , Sotiris Moschoyiannis

Regulatory networks (RNs) are a well-accepted modelling formalism in computational systems biology. The control of RNs is currently receiving a lot of attention because it provides a computational basis for cell reprogramming -- an…

Systems and Control · Electrical Eng. & Systems 2022-03-01 Luboš Brim , Samuel Pastva , David Šafránek , Eva Šmijáková

Probabilistic Boolean Networks (PBNs) have been previously proposed so as to gain insights into complex dy- namical systems. However, identification of large networks and of the underlying discrete Markov Chain which describes their…

Machine Learning · Computer Science 2018-01-24 Ifigeneia Apostolopoulou , Diana Marculescu

A Boolean network is a discrete dynamical system operating on vectors of Boolean variables. The action of a Boolean network can be conveniently expressed as a system of Boolean update functions, computing the new values for each component…

Formal Languages and Automata Theory · Computer Science 2023-03-02 Artiom Alhazov , Vincent Ferrari-Dominguez , Rudolf Freund , Nicolas Glade , Sergiu Ivanov

Boolean network (BN) is a simple model widely used to study complex dynamic behaviour of biological systems. Nonetheless, it might be difficult to gather enough data to precisely capture the behavior of a biological system into a set of…

Molecular Networks · Quantitative Biology 2020-09-02 Lubos Brim , Samuel Pastva , David Safranek , Eva Smijakova

Synchronization is essential for the stability and coordinated operation of complex networked systems. Pinning control, which selectively controls a subset of nodes, provides a scalable solution to enhance network synchronizability.…

Systems and Control · Electrical Eng. & Systems 2025-04-11 Ziang Mao , Tianlong Fan , Linyuan Lü

Probabilistic Boolean networks (PBNs) is a well-established computational framework for modelling biological systems. The steady-state dynamics of PBNs is of crucial importance in the study of such systems. However, for large PBNs, which…

Computational Engineering, Finance, and Science · Computer Science 2016-10-26 Andrzej Mizera , Jun Pang , Qixia Yuan

It has been shown that self-triggered control has the ability to reduce computational loads and deal with the cases with constrained resources by properly setting up the rules for updating the system control when necessary. In this paper,…

Systems and Control · Electrical Eng. & Systems 2020-07-07 Min Meng , Gaoxi Xiao , Daizhan Cheng

Probabilistic Boolean networks (PBNs) is a widely used computational framework for modelling biological systems. The steady-state dynamics of PBNs is of special interest in the analysis of biological systems. However, obtaining the…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-09-01 Andrzej Mizera , Jun Pang , Qixia Yuan

Boolean networks are discrete dynamical systems in which the state (zero or one) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to…

Molecular Networks · Quantitative Biology 2012-02-28 Andrew Pomerance , Michelle Girvan , Ed Ott
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