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Epidemic models describe the evolution of a communicable disease over time. These models are often modified to include the effects of interventions (control measures) such as vaccination, social distancing, school closings etc. Many such…

Methodology · Statistics 2026-01-27 Heejong Bong , Valérie Ventura , Larry Wasserman

Big Bayes is the computationally intensive co-application of big data and large, expressive Bayesian models for the analysis of complex phenomena in scientific inference and statistical learning. Standing as an example, Bayesian…

Myriad experiments have identified an important role for $\rm CD8^+$ T cell response mechanisms in determining recovery from influenza A virus infection. Animal models of influenza infection further implicate multiple elements of the immune…

Influenza-like illness (ILI) places a heavy social and economic burden on our society. Traditionally, ILI surveillance data is updated weekly and provided at a spatially coarse resolution. Producing timely and reliable high-resolution…

Other Statistics · Statistics 2020-02-13 Lijing Wang , Jiangzhuo Chen , Madhav Marathe

Conventional surveillance systems for monitoring infectious diseases, such as influenza, face challenges due to shortage of skilled healthcare professionals, remoteness of communities and absence of communication infrastructures.…

Machine Learning · Computer Science 2018-11-28 Oguzhan Gencoglu , Miikka Ermes

Mathematical and computational modeling approaches are increasingly used as quantitative tools in the analysis and forecasting of infectious disease epidemics. The growing need for realism in addressing complex public health questions is…

Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

We introduce a general, flexible, parametric survival modelling framework which encompasses key shapes of hazard function (constant, increasing, decreasing, up-then-down, down-then-up), various common survival distributions (log-logistic,…

Methodology · Statistics 2019-01-11 Kevin Burke , M. C. Jones , Angela Noufaily

The application of models to assess the risk of the physical impacts of weather and climate and their subsequent consequences for society and business is of the utmost importance in our changing climate. The operation of such models is…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-09-28 Blair Edwards , Paolo Fraccaro , Nikola Stoyanov , Nelson Bore , Julian Kuehnert , Kommy Weldemariam , Anne Jones

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

We propose an approach based on a combination of physical, chemical, and mathematical methods to identify and characterize virulent influenza A viruses (IAVs) through the analysis of the hemagglutinin protein. These methods include the…

Quantitative Methods · Quantitative Biology 2024-11-08 Meitner Cadena , Alejandro Yerovi

The current survey paper concerns stochastic mathematical models for the spread of infectious diseases. It starts with the simplest setting of a homogeneous population in which a transmittable disease spreads during a short outbreak.…

Applications · Statistics 2018-01-30 Tom Britton

The networked structure of contacts shapes the spreading of epidemic processes. Recent advances on network theory have improved our understanding of the epidemic processes at large scale. The relevance of several considerations still needs…

Physics and Society · Physics 2019-02-21 Sergio Gómez , Alberto Fernández , Sandro Meloni , Alex Arenas

We study a model for the spread of an infectious disease which incorporates spatial and temporal effects. The model is a delayed multi-type branching process in which types represent geographic regions while infected individuals reproduce…

Probability · Mathematics 2023-01-27 Andrew Hart , Servet Martínez

Human mobility is a key factor in spatial disease dynamics and related phenomena. In computational models host mobility is typically modelled by diffusion in space or on metapolulation networks. Alternatively, an effective force of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

While often believed to be a passive agent that merely exploits its host's metabolism, influenza virus has recently been shown to actively move across glycan-coated surfaces. This form of enzymatically driven surface motility is currently…

Soft Condensed Matter · Physics 2021-06-02 Falko Ziebert , Igor M. Kulić

We study differential equations describing the spread of influenza A virus infection based on a mathematical model. We look for surface trajectories of the dynamical system in hand and their asymptotic behaviour.

Geometric Topology · Mathematics 2021-11-29 Boldizsar Kalmar

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…

Physics and Society · Physics 2021-07-26 Hugo Dolan , Riccardo Rastelli

Epidemiologists increasingly use causal inference methods that rely on machine learning, as these approaches can relax unnecessary model specification assumptions. While deriving and studying asymptotic properties of such estimators is a…

Methodology · Statistics 2025-02-11 Audrey Renson , Lina Montoya , Dana E. Goin , Iván Díaz , Rachael K. Ross

Disease outbreaks, such as those of Severe Acute Respiratory Syndrome in 2003 and the 2009 pandemic A(H1N1) influenza, have highlighted the potential for airborne transmission in indoor environments. Respirable pathogen-carrying droplets…

Physics and Society · Physics 2012-01-10 M. Robinson , N. I. Stilianakis , Y. Drossinos