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Higher brain function relies upon the ability to flexibly integrate information across specialized communities of brain regions, however it is unclear how this mechanism manifests over time. In this study, we use time-resolved network…

Mediation analysis has become an important tool in the behavioral sciences for investigating the role of intermediate variables that lie in the path between a randomized treatment and an outcome variable. The influence of the intermediate…

Anxiety includes behavioural, physiological, and subjective components that do not always align, and it remains unclear whether these dimensions are supported by distinct intrinsic brain networks. Guided by the two-system framework, we…

Neurons and Cognition · Quantitative Biology 2026-05-04 Shruti Kinger , Mrinmoy Chakrabarty

Cerebral autoregulation (CA) is a fundamental mechanism that modulates cerebrovascular resistance, primarily by regulating the diameter of small cerebral vessels to maintain stable cerebral blood flow (CBF) in response to fluctuations in…

Medical Physics · Physics 2025-09-15 Qi Zhang , Meng-di Yang , Xuan-hao Xu , Xiu-li Xu , Shuai Tian , Li-ling Hao

Results of an experiment are presented whose aim is to explore the relationship between respiration and cerebral oxygenation. Measurements of end tidal CO2 (EtCO2) were taken simultaneously with cerebral oxygen saturation (rSO2) using the…

Medical Physics · Physics 2011-03-30 Alexander Gersten , Dov Heimer , Amir Raz

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

Quantitative Methods · Quantitative Biology 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

Reactive hyperemia is a well-established technique for the non-invasive evaluation of the peripheral microcirculatory function, measured as the magnitude of limb re-perfusion after a brief period of ischemia. Despite widespread adoption by…

Tissues and Organs · Quantitative Biology 2023-02-03 Albertoo Coccarelli , Michael D. Nelson

Interactions between the brain and body are of fundamental importance for human behavior and health. Functional magnetic resonance imaging (fMRI) captures whole-brain activity noninvasively, and modeling how fMRI signals interact with…

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Medical Physics · Physics 2019-03-11 Andrea Saglietto , Stefania Scarsoglio , Luca Ridolfi , Fiorenzo Gaita , Matteo Anselmino

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

Fluid Dynamics · Physics 2023-07-18 Lahcen Akerkouch , Trung Bao Le

The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…

Tissues and Organs · Quantitative Biology 2022-11-07 Gideon Idumah , Erkki Somersalo , Daniela Calvetti

Computer-supported simulation enables a practical alternative for medical training purposes. This study investigates the co-occurrence of facial-recognition-derived emotions and socially shared regulation of learning (SSRL) interactions in…

Human-Computer Interaction · Computer Science 2025-10-21 Xiaoshan Huang , Tianlong Zhong , Haolun Wu , Yeyu Wang , Ethan Churchill , Xue Liu , David Williamson Shaffer

Functional magnetic resonance imaging (fMRI) provides an indirect measurement of neuronal activity via hemodynamic responses that vary across brain regions and individuals. Ignoring this hemodynamic variability can bias downstream…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 William Consagra , Eardi Lila

Cerebral aneurysm progression is a result of a complex interplay of the biomechanical and clinical risk factors that drive aneurysmal growth and rupture. Subjects with multiple aneurysms are unique cases wherein clinical risk factors are…

Medical Physics · Physics 2022-12-26 Tanmay C. Shidhore , Aaron A. Cohen-Gadol , Vitaliy L. Rayz , Ivan C. Christov

Cerebral arterial blood flow (CABF) can be investigated in few seconds without any synchronization by Real-Time phase contrast. Significant changes in CABF were found between expiration and inspiration during normal breathing of healthy…

Signal Processing · Electrical Eng. & Systems 2022-07-27 Pan Liu , Sidy Fall , Serge Metanbou , Olivier Balédent

A healthy human brain is perfused with blood flowing laminarly through cerebral vessels, providing brain tissue with substrates such as oxygen and glucose. Under normal conditions, cerebral blood flow is controlled by autoregulation as well…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Miroslaw Latka , Malgorzata Turalska , Waldemar Kolodziej , Dariusz Latka , Brahm Goldstein , Bruce J. West

Brain signal visualization has emerged as an active research area, serving as a critical interface between the human visual system and computer vision models. Although diffusion models have shown promise in analyzing functional magnetic…

Computer Vision and Pattern Recognition · Computer Science 2023-12-19 Bohan Zeng , Shanglin Li , Xuhui Liu , Sicheng Gao , Xiaolong Jiang , Xu Tang , Yao Hu , Jianzhuang Liu , Baochang Zhang

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Reliable communication in confined environments, such as blood vessels or industrial pipelines, remain challenging due to signal attenuation and limited sensor accessibility. Therefore, this work investigates microbubbles as robust…

Signal Processing · Electrical Eng. & Systems 2026-04-17 Annika Tjabben , Carolin Conrad , Hans D. Schotten

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

Disordered Systems and Neural Networks · Physics 2020-03-11 Takashi Hayakawa , Tomoki Fukai