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Advances in neuroscience and artificial intelligence have enabled preliminary decoding of brain activity. However, despite the progress, the interpretability of neural representations remains limited. A significant challenge arises from the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Hasib Aslam , Muhammad Talal Faiz , Muhammad Imran Malik

In the last decades, the interest to understand the connection between brain and body has grown notably. For example, in psychoneuroimmunology many studies associate stress, arising from many different sources and situations, to changes in…

Quantitative Methods · Quantitative Biology 2022-07-27 Maria Elena Gonzalez Herrero , Christian Kuehn

Accurate MR signal simulation, including microvascular structures and water diffusion, is crucial for MRI techniques like fMRI BOLD modeling and MR vascular Fingerprinting (MRF), which use susceptibility effects on MR signals for tissue…

We review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse-graining over an increasing diffusion length scale. From this perspective, we view research on…

Biological Physics · Physics 2018-04-20 Dmitry S. Novikov , Els Fieremans , Sune N. Jespersen , Valerij G. Kiselev

Despite recent advances in brain research, understanding the various signals for pain and pain intensities in the brain cortex is still a complex task due to temporal and spatial variations of brain hemodynamics. In this paper we have…

Neurons and Cognition · Quantitative Biology 2015-07-28 Raul Fernandez Rojas , Xu Huang , Keng Liang Ou , Dat Tran , Sheikh Md. Rabiul Islam

Despite participants engaging in unimodal stimuli, such as watching images or silent videos, recent work has demonstrated that multi-modal Transformer models can predict visual brain activity impressively well, even with incongruent…

Neurons and Cognition · Quantitative Biology 2025-05-27 Subba Reddy Oota , Khushbu Pahwa , Mounika Marreddy , Maneesh Singh , Manish Gupta , Bapi S. Raju

Naturalistic fMRI characterizes the brain as a dynamic predictive engine driven by continuous sensory streams. However, modeling the causal forward evolution in realistic neural simulation is impeded by the timescale mismatch between…

Neurons and Cognition · Quantitative Biology 2026-02-05 Xuanhua Yin , Runkai Zhao , Lina Yao , Weidong Cai

We tested the hypothesis that simple exercises may significantly increase cerebral blood flow (CBF) and/or cerebral oxygenation. Eighteen subjects ranging in age from nineteen to thirty nine participated in a four-stage study during which…

Medical Physics · Physics 2011-03-30 Alexander Gersten , Jacqueline Perle , Amir Raz , Robert Fried

Anatomy of the human brain constrains the formation of large-scale functional networks. Here, given measured brain activity in gray matter, we interpolate these functional signals into the white matter on a structurally-informed…

Neurons and Cognition · Quantitative Biology 2019-08-27 Anjali Tarun , Hamid Behjat , David Abramian , Dimitri Van De Ville

Migraine, a prevalent neurological disorder, has been associated with various ocular manifestations suggestive of neuronal and microvascular deficits. However, there is limited understanding of the extent to which retinal imaging may…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Feilong Tang , Matt Trinh , Annita Duong , Angelica Ly , Fiona Stapleton , Zhe Chen , Zongyuan Ge , Imran Razzak

Despite numerous research efforts, the precise mechanisms of concussion have yet to be fully uncovered. Clinical studies on high-risk populations, such as contact sports athletes, have become more common and give insight on the link between…

The technology of functional Magnetic Resonance Imaging (fMRI) based on Blood Oxygen Level Dependent (BOLD) signal has been widely used in clinical treatments and brain function researches. The BOLD signal has to be preprocessed before…

Neurons and Cognition · Quantitative Biology 2017-12-29 Yunxiang Ge , Yu Pan , Weibei Dou

Model-based reinforcement learning is attractive for sequential decision-making because it explicitly estimates reward and transition models and then supports planning through simulated rollouts. In offline settings with hidden confounding,…

Machine Learning · Computer Science 2026-04-08 Nishanth Venkatesh , Andreas A. Malikopoulos

Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mattia Litrico , Francesco Guarnera , Mario Valerio Giuffrida , Daniele Ravì , Sebastiano Battiato

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

The stress-free state (SFS) of red blood cells (RBCs) is a fundamental reference configuration for the calibration of computational models, yet it remains unknown. Current experimental methods cannot measure the SFS of cells without…

Computational Engineering, Finance, and Science · Computer Science 2023-04-04 Lucas Amoudruz , Athena Economides , Georgios Arampatzis , Petros Koumoutsakos

Functional magnetic resonance imaging (fMRI) techniques have contributed significantly to our understanding of brain function. Current methods are based on the analysis of \emph{gradual and continuous} changes in the brain blood oxygenated…

Neurons and Cognition · Quantitative Biology 2011-07-25 Enzo Tagliazucchi , Pablo Balenzuela , Daniel Fraiman , Dante R. Chialvo

Among the major factors controlling the cerebral blood flow (CBF), the effect of PaCO2 is peculiar in that it violates autoregulatory CBF mechanisms and allows to explore the full range of the CBF. This research resulted in a simple…

Medical Physics · Physics 2011-03-30 Alexander Gersten

This thesis is dedicated to the statistical analysis of multi-sub ject fMRI data, with the purpose of identifying bain structures involved in certain cognitive or sensori-motor tasks, in a reproducible way across sub jects. To overcome…

Applications · Statistics 2010-05-19 Merlin Keller , Alexis Roche , Marc Lavielle

Recent development of quantitative myocardial blood flow (MBF) mapping allows direct evaluation of absolute myocardial perfusion, by computing pixel-wise flow maps. Clinical studies suggest quantitative evaluation would be more desirable…

Quantitative Methods · Quantitative Biology 2020-06-01 Hui Xue , Rhodri Davies , Louis AE Brown , Kristopher D Knott , Tushar Kotecha , Marianna Fontana , Sven Plein , James C Moon , Peter Kellman
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