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Haplotyping is the bioinformatics problem of predicting likely haplotypes based on given genotypes. It can be approached using Gusfield's perfect phylogeny haplotyping (PPH) method for which polynomial and linear time algorithms exist.…

Computational Complexity · Computer Science 2009-05-06 Michael Elberfeld

Multi-hop machine reading comprehension is a challenging task in natural language processing as it requires more reasoning ability across multiple documents. Spectral models based on graph convolutional networks have shown good inferring…

Computation and Language · Computer Science 2023-07-24 Peng Gao , Feng Gao , Peng Wang , Jian-Cheng Ni , Fei Wang , Hamido Fujita

Semi-supervised learning (SSL) has been extensively studied to improve the generalization ability of deep neural networks for visual recognition. To involve the unlabelled data, most existing SSL methods are based on common density-based…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Suichan Li , Bin Liu , Dongdong Chen , Qi Chu , Lu Yuan , Nenghai Yu

Computational pathology tasks have some unique characterises such as multi-gigapixel images, tedious and frequently uncertain annotations, and unavailability of large number of cases [13]. To address some of these issues, we present Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Nima Hatami

Cohort studies are of significant importance in the field of healthcare analysis. However, existing methods typically involve manual, labor-intensive, and expert-driven pattern definitions or rely on simplistic clustering techniques that…

Machine Learning · Computer Science 2024-06-21 Qingpeng Cai , Kaiping Zheng , H. V. Jagadish , Beng Chin Ooi , James Yip

Self-assembly of dilute sequence-defined macromolecules is a complex phenomenon in which the local arrangement of chemical moieties can lead to the formation of long-range structure. The dependence of this structure on the sequence…

Soft Condensed Matter · Physics 2022-06-08 Debjyoti Bhattacharya , Devon C. Kleeblatt , Antonia Statt , Wesley F. Reinhart

Satellite DNA are long tandemly repeating sequences in a genome and may be organized as high-order repeats (HORs). They are enriched in centromeres and are challenging to assemble. Existing algorithms for identifying satellite repeats…

Genomics · Quantitative Biology 2023-04-20 Yujie Zhang , Justin Chu , Haoyu Cheng , Heng Li

This paper tackles the challenging problem of hyperspectral (HS) image denoising. Unlike existing deep learning-based methods usually adopting complicated network architectures or empirically stacking off-the-shelf modules to pursue…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Jinhui Hou , Zhiyu Zhu , Hui Liu , Junhui Hou

Given a graph where every node has certain attributes associated with it and some nodes have labels associated with them, Collective Classification (CC) is the task of assigning labels to every unlabeled node using information from the node…

Machine Learning · Computer Science 2018-11-14 Priyesh Vijayan , Yash Chandak , Mitesh M. Khapra , Srinivasan Parthasarathy , Balaraman Ravindran

Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

Quantitative Methods · Quantitative Biology 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

Collaborative learning, which enables collaborative and decentralized training of deep neural networks at multiple institutions in a privacy-preserving manner, is rapidly emerging as a valuable technique in healthcare applications. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Liangqiong Qu , Niranjan Balachandar , Miao Zhang , Daniel Rubin

Pairwise alignment of DNA sequencing data is a ubiquitous task in bioinformatics and typically represents a heavy computational burden. State-of-the-art approaches to speed up this task use hashing to identify short segments (k-mers) that…

Machine Learning · Computer Science 2021-02-16 Govinda M. Kamath , Tavor Z. Baharav , Ilan Shomorony

Several recent works have shown that image descriptors produced by deep convolutional neural networks provide state-of-the-art performance for image classification and retrieval problems. It has also been shown that the activations from the…

Computer Vision and Pattern Recognition · Computer Science 2015-10-27 Artem Babenko , Victor Lempitsky

In biological research, fluorescence staining is a key technique to reveal the locations and morphology of subcellular structures. However, it is slow, expensive, and harmful to cells. In this paper, we model it as a deep learning task…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Donghao Zhou , Chunbin Gu , Junde Xu , Furui Liu , Qiong Wang , Guangyong Chen , Pheng-Ann Heng

We introduce a new concept of a subgraph class called a superbubble for analyzing assembly graphs, and propose an efficient algorithm for detecting it. Most assembly algorithms utilize assembly graphs like the de Bruijn graph or the overlap…

Data Structures and Algorithms · Computer Science 2013-08-02 Taku Onodera , Kunihiko Sadakane , Tetsuo Shibuya

Mixed communities of organisms are found in many environments (from the human gut to marine ecosystems) and can have profound impact on human health and the environment. Metagenomics studies the genomic material of such communities through…

Genomics · Quantitative Biology 2021-12-23 Hansheng Xue , Vijini Mallawaarachchi , Yujia Zhang , Vaibhav Rajan , Yu Lin

Persistent homology theory is a relatively new but powerful method in data analysis. Using simplicial complexes, classical persistent homology is able to reveal high dimensional geometric structures of datasets, and represent them as…

Algebraic Topology · Mathematics 2023-12-05 Yaru Gao , Yan Xu , Fengchun Lei

Complex networks often exhibit community structure, with communities corresponding to denser subgraphs in which nodes are closely linked. When modelling systems where interactions extend beyond node pairs to arbitrary numbers of nodes,…

Physics and Society · Physics 2025-10-16 Bianka Kovács , Barnabás Benedek , Gergely Palla

Computational topologists recently developed a method, called persistent homology to analyze data presented in terms of similarity or dissimilarity. Indeed, persistent homology studies the evolution of topological features in terms of a…

Quantitative Methods · Quantitative Biology 2017-08-01 Pavel Petrov , Stephen T Rush , Zhichun Zhai , Christine H Lee , Peter T Kim , Giseon Heo

Enlarged lymph nodes (LNs) can provide important information for cancer diagnosis, staging, and measuring treatment reactions, making automated detection a highly sought goal. In this paper, we propose a new algorithm representation of…

Computer Vision and Pattern Recognition · Computer Science 2014-08-15 Ari Seff , Le Lu , Kevin M. Cherry , Holger Roth , Jiamin Liu , Shijun Wang , Joanne Hoffman , Evrim B. Turkbey , Ronald M. Summers
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