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Related papers: Moran models and Wright--Fisher diffusions with se…

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The Wright--Fisher diffusion is important in population genetics in modelling the evolution of allele frequencies over time subject to the influence of biological phenomena such as selection, mutation, and genetic drift. Simulating paths of…

Populations and Evolution · Quantitative Biology 2023-01-16 Jaromir Sant , Paul A. Jenkins , Jere Koskela , Dario Spanò

We study a generalization of the Wright--Fisher model in which some individuals adopt a behavior that is harmful to others without any direct advantage for themselves. This model is motivated by studies of spiteful behavior in nature,…

Probability · Mathematics 2015-03-18 Ludovic Goudenège , Pierre-André Zitt

Muller's ratchet is a paradigmatic model for the accumulation of deleterious mutations in a population of finite size. A click of the ratchet occurs when all individuals with the least number of deleterious mutations are lost irreversibly…

Populations and Evolution · Quantitative Biology 2013-11-20 Jakob J. Metzger , Stephan Eule

Demographic models built from genetic data play important roles in illuminating prehistorical events and serving as null models in genome scans for selection. We introduce an inference method based on the joint frequency spectrum of genetic…

Populations and Evolution · Quantitative Biology 2010-05-10 Ryan N. Gutenkunst , Ryan D. Hernandez , Scott H. Williamson , Carlos D. Bustamante

Natural populations often show enhanced genetic drift consistent with a strong skew in their offspring number distribution. The skew arises because the variability of family sizes is either inherently strong or amplified by population…

Populations and Evolution · Quantitative Biology 2022-01-13 Takashi Okada , Oskar Hallatschek

We investigate the behaviour of the genealogy of a Wright-Fisher population model under the influence of a strong seed-bank effect. More precisely, we consider a simple seed-bank age distribution with two atoms, leading to either classical…

Probability · Mathematics 2014-03-13 Jochen Blath , Bjarki Eldon , Adrián González Casanova , Noemi Kurt

The purpose of this Note is twofold: First, we introduce the general formalism of evolutionary genetics dynamics involving fitnesses, under both the deterministic and stochastic setups, and chiefly in discrete-time. In the process, we…

Quantitative Methods · Quantitative Biology 2015-05-14 Thierry Huillet

The Ancestral Selection Graph (ASG) is an important genealogical process which extends the well-known Kingman coalescent to incorporate natural selection. We show that the number of lineages of the ASG with and without mutation is…

Probability · Mathematics 2020-12-23 Philip A. Hanson , Paul A. Jenkins , Jere Koskela , Dario Spanò

A forward diffusion equation describing the evolution of the allele frequency spectrum is presented. The influx of mutations is accounted for by imposing a suitable boundary condition. For a Wright-Fisher diffusion with or without selection…

Populations and Evolution · Quantitative Biology 2007-05-23 Steven N. Evans , Yelena Shvets , Montgomery Slatkin

Migrations have played an important role in shaping the genetic diversity of human populations. Understanding genomic data thus requires careful modeling of historical gene flow. Here we consider the effect of relatively recent population…

Populations and Evolution · Quantitative Biology 2012-04-26 Simon Gravel

We consider diffusion processes x_{t} on the unit interval. Doob-transformation techniques consist of a selection of x_{t}-paths procedure. The law of the transformed process is the one of a branching diffusion system of particles, each…

Quantitative Methods · Quantitative Biology 2011-07-15 Thierry Huillet

The paper is devoted to the study of the asymptotic behaviour of Moran process in random environment, say random selection. In finite population, the Moran process may be degenerate in finite time, thus we will study its limiting process in…

Probability · Mathematics 2019-11-05 Arnaud Guillin , Arnaud Personne , Edouard Strickler

We consider a meanfield system of interacting Fisher-Wright diffusions with selection and rare mutation on the geographic space $\{1,2,...,N\}$. The type 1 has fitness 0, type 2 has fitness 1 and (rare) mutation occurs from type 1 to 2 at…

Probability · Mathematics 2011-04-05 Donald A. Dawson , Andreas Greven

The stationary sampling distribution of a neutral decoupled Moran or Wright-Fisher diffusion with neutral mutations is known to first order for a general rate matrix with small but otherwise unconstrained mutation rates. Using this…

Populations and Evolution · Quantitative Biology 2020-05-07 Claus Vogl , Lynette C. Mikula , Conrad J. Burden

The Moran model with recombination is considered, which describes the evolution of the genetic composition of a population under recombination and resampling. There are $n$ sites (or loci), a finite number of letters (or alleles) at every…

Probability · Mathematics 2018-11-01 Mareike Esser , Sebastian Probst , Ellen Baake

The goal of this paper is to develop a theory of graphon-valued stochastic processes, and to construct and analyse a natural class of such processes arising from population genetics. We consider finite populations where individuals change…

Probability · Mathematics 2019-08-20 Siva Athreya , Frank den Hollander , Adrian Röllin

Both evolution and ecology have long been concerned with the impact of variable environmental conditions on observed levels of genetic diversity within and between species. We model the evolution of a quantitative trait under selection that…

Populations and Evolution · Quantitative Biology 2014-11-17 Hannes Svardal , Claus Rueffler , Joachim Hermisson

We study the evolution of the population genealogy in the classic neutral Moran Model of finite size and in discrete time. The stochastic transformations that shape a Moran population can be realized directly on its genealogy and give rise…

Populations and Evolution · Quantitative Biology 2019-02-08 Johannes Wirtz , Thomas Wiehe

We consider a stochastic model describing a constant size $N$ population that may be seen as a directed polymer in random medium with $N$ sites in the transverse direction. The population dynamics is governed by a noisy traveling wave…

Probability · Mathematics 2016-06-07 Aser Cortines

A simulation model of a population having internal (genetic) structure is presented. The population is subject to selection pressure coming from the environment which is the same in the whole system but changes in time. Reproduction has a…

Adaptation and Self-Organizing Systems · Physics 2012-08-31 Andrzej Pekalski , Marcel Ausloos