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Heterogeneous treatment effects (HTEs) are commonly identified during randomized controlled trials (RCTs). Identifying subgroups of patients with similar treatment effects is of high interest in clinical research to advance precision…

Machine Learning · Computer Science 2022-12-06 Peniel N. Argaw , Elizabeth Healey , Isaac S. Kohane

The histogram method is a powerful non-parametric approach for estimating the probability density function of a continuous variable. But the construction of a histogram, compared to the parametric approaches, demands a large number of…

Machine Learning · Statistics 2015-12-29 Hideaki Kim , Hiroshi Sawada

Groundwater in the Densu Basin is increasingly threatened by heavy metal contamination, but conventional methods fail to capture the statistical complexity and spatial heterogeneity of pollution indicators. A key challenge is modelling the…

Machine Learning · Computer Science 2026-05-04 T. Ansah-Narh , G. Y. Afrifa , J. B. Tandoh , K. Asare , M. Addi , K. E. Yorke , D. M. A. Akpoley , K. Aidoo , S. K. Fosuhene

Ensemble density functional theory is a promising method for the efficient and accurate calculation of excitations of quantum systems, at least if useful functionals can be developed to broaden its domain of practical applicability. Here,…

Chemical Physics · Physics 2017-12-25 Tim Gould , Stefano Pittalis

Kernel density estimation (KDE) is a popular statistical technique for estimating the underlying density distribution with minimal assumptions. Although they can be shown to achieve asymptotic estimation optimality for any input…

Computation · Statistics 2011-02-15 Dongryeol Lee , Alexander G. Gray , Andrew W. Moore

Heterogeneous treatment effect (HTE) estimation is critical in medical research. It provides insights into how treatment effects vary among individuals, which can provide statistical evidence for precision medicine. While most existing…

Machine Learning · Statistics 2025-04-25 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

We revisit the problem of estimating the center of symmetry $\theta$ of an unknown symmetric density $f$. Although Stone (1975), Van Eden (1970), and Sacks (1975) constructed adaptive estimators of $\theta$ in this model, their estimators…

Statistics Theory · Mathematics 2019-11-15 Nilanjana Laha

Analyzing data from multiple sources offers valuable opportunities to improve the estimation efficiency of causal estimands. However, this analysis also poses many challenges due to population heterogeneity and data privacy constraints.…

Methodology · Statistics 2025-10-23 Rong Zhao , Jason Falvey , Xu Shi , Vernon M. Chinchilli , Chixiang Chen

Artificial neural networks have been successfully applied to a variety of machine learning tasks, including image recognition, semantic segmentation, and machine translation. However, few studies fully investigated ensembles of artificial…

Machine Learning · Statistics 2017-04-07 Cheng Ju , Aurélien Bibaut , Mark J. van der Laan

It is demonstrated that the classical Hough transform with shift-elevation parametrization of digital straight lines has additive complexity of at most $\mathcal{O}(n^3 / \log n)$ on a $n\times n$ image. The proof is constructive and uses…

Computational Complexity · Computer Science 2018-02-20 Timur M. Khanipov

The estimation of probability densities based on available data is a central task in many statistical applications. Especially in the case of large ensembles with many samples or high-dimensional sample spaces, computationally efficient…

Methodology · Statistics 2017-05-04 Daniel W. Meyer

A well-known issue of local (adaptive) histogram equalization (LHE) is over-enhancement (i.e., generation of spurious details) in homogenous areas of the image. In this paper, we show that the LHE problem has many solutions due to the…

Computer Vision and Pattern Recognition · Computer Science 2009-09-14 Alireza Avanaki

The increasing scientific attention given to precision medicine based on real-world data has led many recent studies to clarify the relationships between treatment effects and patient characteristics. However, this is challenging because of…

Methodology · Statistics 2022-06-20 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

This paper studies quantitative deviation bounds for statistical ensembles evolving under the one-parameter flow of a nearly integrable Hamiltonian system. Combining Nekhoroshev-type stability estimates with phase-mixing arguments, we…

Dynamical Systems · Mathematics 2026-02-23 Xinyu Liu , Yong Li

Reliable inference from complex survey samples can be derailed by outliers and high-leverage observations induced by unequal inclusion probabilities and calibration. We develop a minimum Hellinger distance estimator (MHDE) for parametric…

Statistics Theory · Mathematics 2026-03-18 David Kepplinger , Anand N. Vidyashankar

Efficient Bayesian model selection relies on the model evidence or marginal likelihood, whose computation often requires evaluating an intractable integral. The harmonic mean estimator (HME) has long been a standard method of approximating…

Computation · Statistics 2025-12-23 Dana Naderi , Christian P Robert , Kaniav Kamary , Darren Wraith

Mutual learning, in which multiple networks learn by sharing their knowledge, improves the performance of each network. However, the performance of ensembles of networks that have undergone mutual learning does not improve significantly…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Naoki Okamoto , Soma Minami , Tsubasa Hirakawa , Takayoshi Yamashita , Hironobu Fujiyoshi

Ensemble methods in machine learning aim to improve prediction accuracy by combining multiple models. This is achieved by ensuring diversity among predictors to capture different data aspects. Homogeneous ensembles use identical models,…

Quantum Physics · Physics 2025-11-04 Emiliano Tolotti , Enrico Blanzieri , Davide Pastorello

Background: Breast cancer has the highest prevalence in women globally. The classification and diagnosis of breast cancer and its histopathological images have always been a hot spot of clinical concern. In Computer-Aided Diagnosis (CAD),…

Computer Vision and Pattern Recognition · Computer Science 2022-05-11 Yuchao Zheng , Chen Li , Xiaomin Zhou , Haoyuan Chen , Hao Xu , Yixin Li , Haiqing Zhang , Xiaoyan Li , Hongzan Sun , Xinyu Huang , Marcin Grzegorzek

This paper rethinks image histogram matching (HM) and proposes a differentiable and parametric HM preprocessing for a downstream classifier. Convolutional neural networks have demonstrated remarkable achievements in classification tasks.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Rikuto Otsuka , Yuho Shoji , Yuka Ogino , Takahiro Toizumi , Atsushi Ito