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Accurate heterogeneous treatment effect (HTE) estimation is essential for personalized recommendations, making it important to evaluate and compare HTE estimators. Traditional assessment methods are inapplicable due to missing…

Methodology · Statistics 2024-12-30 Zijun Gao

The heterogeneity of treatment effect (HTE) lies at the heart of precision medicine. Randomized controlled trials are gold-standard for treatment effect estimation but are typically underpowered for heterogeneous effects. In contrast, large…

Methodology · Statistics 2024-11-14 Shu Yang , Siyi Liu , Donglin Zeng , Xiaofei Wang

Ensemble learning is a mainstay in modern data science practice. Conventional ensemble algorithms assign to base models a set of deterministic, constant model weights that (1) do not fully account for individual models' varying accuracy…

Methodology · Statistics 2019-04-02 Jeremiah Zhe Liu , John Paisley , Marianthi-Anna Kioumourtzoglou , Brent A. Coull

White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional…

Computer Vision and Pattern Recognition · Computer Science 2018-09-20 Hongwei Li , Gongfa Jiang , Jianguo Zhang , Ruixuan Wang , Zhaolei Wang , Wei-Shi Zheng , Bjoern Menze

Deep Neural Networks (DNNs) have achieved remarkable success in a variety of tasks, especially when it comes to prediction accuracy. However, in complex real-world scenarios, particularly in safety-critical applications, high accuracy alone…

Artificial Intelligence · Computer Science 2024-05-31 Han Liu , Peng Cui , Bingning Wang , Jun Zhu , Xiaolin Hu

We study the assessment of the accuracy of heterogeneous treatment effect (HTE) estimation, where the HTE is not directly observable so standard computation of prediction errors is not applicable. To tackle the difficulty, we propose an…

Methodology · Statistics 2020-03-10 Zijun Gao , Trevor Hastie , Robert Tibshirani

Asymptotic efficiency of targeted maximum likelihood estimators (TMLE) of target features of the data distribution relies on a a second order remainder being asymptotically negligible. In previous work we proposed a nonparametric MLE termed…

Statistics Theory · Mathematics 2021-07-02 Mark van der Laan , Zeyi Wang , Lars van der Laan

Ensemble clustering integrates a set of base clustering results to generate a stronger one. Existing methods usually rely on a co-association (CA) matrix that measures how many times two samples are grouped into the same cluster according…

Machine Learning · Computer Science 2023-02-24 Yuheng Jia , Sirui Tao , Ran Wang , Yongheng Wang

We introduce the Meta Highly-Adaptive-Lasso Minimum Loss Estimator (M-HAL-MLE), a novel ensemble approach for estimating functional parameters of realistically modeled data distribution from independent and identically distributed…

Methodology · Statistics 2025-07-28 Zeyi Wang , Wenxin Zhang , Brian S Caffo , Martin Lindquist , Mark van der Laan

Monitoring biodiversity is paramount to manage and protect natural resources. Collecting images of organisms over large temporal or spatial scales is a promising practice to monitor the biodiversity of natural ecosystems, providing large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 S. Kyathanahally , T. Hardeman , M. Reyes , E. Merz , T. Bulas , P. Brun , F. Pomati , M. Baity-Jesi

We propose HSMUCE (heterogeneous simultaneous multiscale change-point estimator) for the detection of multiple change-points of the signal in a heterogeneous gaussian regression model. A piecewise constant function is estimated by…

Methodology · Statistics 2016-02-08 Florian Pein , Hannes Sieling , Axel Munk

A central goal of causal inference is to detect and estimate the treatment effects of a given treatment or intervention on an outcome variable of interest, where a member known as the heterogeneous treatment effect (HTE) is of growing…

Statistics Theory · Mathematics 2020-10-27 Zijun Gao , Yanjun Han

The conventional reversible data hiding (RDH) algorithms often consider the host as a whole to embed a secret payload. In order to achieve satisfactory rate-distortion performance, the secret bits are embedded into the noise-like component…

Multimedia · Computer Science 2021-10-08 Hanzhou Wu , Wei Wang , Jing Dong , Hongxia Wang

One of the fundamental problems in machine learning is the estimation of a probability distribution from data. Many techniques have been proposed to study the structure of data, most often building around the assumption that observations…

Machine Learning · Statistics 2013-02-22 Oren Rippel , Ryan Prescott Adams

Machine learning has emerged as a promising approach to path loss prediction, yet its effectiveness often degrades when measurement data are scarce. To address this limitation, we propose an ensemble-based machine learning framework that…

Signal Processing · Electrical Eng. & Systems 2026-05-26 Ahmed P. Mohamed , Byunghyun Lee , Yaguang Zhang , Christopher R. Anderson , David J. Love , James V. Krogmeier

Learning heterogeneous treatment effects (HTEs) is an important problem across many fields. Most existing methods consider the setting with a single treatment arm and a single outcome metric. However, in many real world domains, experiments…

Machine Learning · Computer Science 2022-06-13 Leon Yao , Caroline Lo , Israel Nir , Sarah Tan , Ariel Evnine , Adam Lerer , Alex Peysakhovich

The efficiency of statistical sampling in broad-histogram Monte Carlo simulations can be considerably improved by optimizing the simulated extended ensemble for fastest equilibration. Here we describe how a recently developed feedback…

Statistical Mechanics · Physics 2007-12-13 Stefan Wessel , Norbert Stoop , Emanuel Gull , Simon Trebst , Matthias Troyer

We introduce the well-tempered ensemble (WTE) which is the biased ensemble sampled by well-tempered metadynamics when the energy is used as collective variable. WTE can be designed so as to have approximately the same average energy as the…

Statistical Mechanics · Physics 2015-05-14 M. Bonomi , M. Parrinello

This article pursues a statistical study of the Hough transform, the celebrated computer vision algorithm used to detect the presence of lines in a noisy image. We first study asymptotic properties of the Hough transform estimator, whose…

Statistics Theory · Mathematics 2007-06-13 Alexander Goldenshluger , Assaf Zeevi

Recent advances in both theory and methods have created opportunities to simulate biomolecular processes more efficiently using adaptive ensemble simulations. Ensemble-based simulations are used widely to compute a number of individual…

Computational Engineering, Finance, and Science · Computer Science 2020-09-14 Vivek Balasubramanian , Travis Jensen , Matteo Turilli , Peter Kasson , Michael Shirts , Shantenu Jha