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To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

The ever-growing speed at which data are generated nowadays, together with the substantial cost of labeling processes cause Machine Learning models to face scenarios in which data are partially labeled. The extreme case where such a…

Machine Learning · Computer Science 2024-07-09 Maria Arostegi , Miren Nekane Bilbao , Jesus L. Lobo , Javier Del Ser

Interpretation and diagnosis of machine learning models have gained renewed interest in recent years with breakthroughs in new approaches. We present Manifold, a framework that utilizes visual analysis techniques to support interpretation,…

Machine Learning · Computer Science 2019-01-18 Jiawei Zhang , Yang Wang , Piero Molino , Lezhi Li , David S. Ebert

The Visual Physics Analysis (VISPA) project defines a toolbox for accessing software via the web. It is based on latest web technologies and provides a powerful extension mechanism that enables to interface a wide range of applications.…

The progression of deep learning and the widespread adoption of sensors have facilitated automatic multi-view fusion (MVF) about the cardiovascular system (CVS) signals. However, prevalent MVF model architecture often amalgamates CVS…

Machine Learning · Computer Science 2024-06-14 Qihan Hu , Daomiao Wang , Hong Wu , Jian Liu , Cuiwei Yang

Improving the throughput of molecular docking, a computationally intensive phase of the virtual screening process, is a highly sought area of research since it has a significant weight in the drug designing process. With such improvements,…

Artificial Intelligence · Computer Science 2013-12-05 Upul Senanayake , Rahal Prabuddha , Roshan Ragel

Application-Specific Instruction-Set Processors (ASIPs) built on the RISC-V architecture offer specialization opportunities for various applications. Existing frameworks are largely designed around fixed instruction extension interfaces and…

Hardware Architecture · Computer Science 2026-04-21 Yuyang Zou , Youwei Xiao , Chenyun Yin , Yansong Xu , Yuhao Luo , Yitian Sun , Ruifan Xu , Renze Chen , Yun Liang

We introduce EvoFlows, a variable-length protein sequence-to-sequence modeling approach designed for protein engineering. Existing protein language models are poorly suited for optimization tasks: autoregressive models require full sequence…

Machine Learning · Computer Science 2026-04-09 Nicolas Deutschmann , Constance Ferragu , Jonathan D. Ziegler , Shayan Aziznejad , Eli Bixby

Dynamic program analysis (also known as profiling) is well-known for its powerful capabilities of identifying performance inefficiencies in software packages. Although a large number of dynamic program analysis techniques are developed in…

Software Engineering · Computer Science 2023-12-29 Qidong Zhao , Milind Chabbi , Xu Liu

The Collective Variables Dashboard is a software tool for real-time, seamless exploration of molecular structures and trajectories in a customizable space of collective variables. The Dashboard arises from the integration of the Collective…

Computational Physics · Physics 2022-02-21 Jérôme Hénin , Laura J. S. Lopes , Giacomo Fiorin

Data-flow analysis is a general technique used to compute information of interest at different points of a program and is considered to be a cornerstone of static analysis. In this thesis, we consider interprocedural data-flow analysis as…

Programming Languages · Computer Science 2023-09-21 Ahmed Khaled Zaher

Molecular dynamics simulations, an indispensable research tool in computational chemistry and materials science, consume a significant portion of the supercomputing cycles around the world. We focus on multi-body potentials and aim at…

Computational Engineering, Finance, and Science · Computer Science 2016-07-12 Markus Höhnerbach , Ahmed E. Ismail , Paolo Bientinesi

We propose a new abstraction set (SynopSet) that has a continuum of visual representations for the explanatory analysis of molecular dynamics simulations (MDS) in the DNA nanotechnology domain. By re-purposing the commonly used progress bar…

Quantitative Methods · Quantitative Biology 2022-05-04 Deng Luo , Alexandre Kouyoumdjian , Ondřej Strnad , Haichao Miao , Ivan Barišić , Ivan Viola

Novel non-volatile memory (NVM) technologies offer high-speed and high-density data storage. In addition, they overcome the von Neumann bottleneck by enabling computing-in-memory (CIM). Various computer architectures have been proposed to…

Cryptography and Security · Computer Science 2023-04-13 Lennart M. Reimann , Felix Staudigl , Rainer Leupers

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

Data preprocessing techniques are devoted to correct or alleviate errors in data. Discretization and feature selection are two of the most extended data preprocessing techniques. Although we can find many proposals for static Big Data…

Databases · Computer Science 2018-10-16 Alejandro Alcalde-Barros , Diego García-Gil , Salvador García , Francisco Herrera

Human-in-the-loop data analysis applications necessitate greater transparency in machine learning models for experts to understand and trust their decisions. To this end, we propose a visual analytics workflow to help data scientists and…

Machine Learning · Statistics 2017-10-03 Josua Krause , Aritra Dasgupta , Jordan Swartz , Yindalon Aphinyanaphongs , Enrico Bertini

Large-scale simulations on supercomputers have become important tools for users. However, their scalability remains a problem due to the huge communication cost among parallel processes. Most of the existing communication latency analysis…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Chongke Bi , Xin Gao , Baofeng Fu , Yuheng Zhao , Siming Chen , Ying Zhao , Lu Yang

Most bioinformatics pipelines consist of software components that are tightly coupled to the logic of the pipeline itself. This limits reusability of the individual components in the pipeline or introduces maintenance overhead when they…

Software Engineering · Computer Science 2021-10-25 Robrecht Cannoodt , Hendrik Cannoodt , Eric Van de Kerckhove , Andy Boschmans , Dries De Maeyer , Toni Verbeiren

Molecular generation conditioned on textual descriptions is a fundamental task in computational chemistry and drug discovery. Existing methods often struggle to simultaneously ensure high-quality, diverse generation and fast inference. In…

Machine Learning · Computer Science 2025-08-08 Md Atik Ahamed , Qiang Ye , Qiang Cheng