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The financial industry faces a significant challenge modeling and risk portfolios: balancing the predictability of advanced machine learning models, neural network models, and explainability required by regulatory entities (such as Office…

Machine Learning · Computer Science 2025-11-10 Rongbin Ye , Jiaqi Chen

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Using machine learning in clinical practice poses hard requirements on explainability, reliability, replicability and robustness of these systems. Therefore, developing reliable software for monitoring critically ill patients requires close…

Software Engineering · Computer Science 2021-03-16 Miroslaw Staron , Helena Odenstedt Hergés , Silvana Naredi , Linda Block , Ali El-Merhi , Richard Vithal , Mikael Elam

Machine learning models are exceptionally effective in capturing complex non-linear relationships of high-dimensional datasets and making accurate predictions. However, their intrinsic ``black-box'' nature makes it difficult to interpret…

Plasma Physics · Physics 2024-07-29 Tadas Pyragius , Cary Colgan , Hazel Lowe , Filip Janky , Matteo Fontana , Yichen Cai , Graham Naylor

Deep learning (DL) has gained popularity in recent years as an effective tool for classifying the current health and predicting the future of industrial equipment. However, most DL models have black-box components with an underlying…

Machine Learning · Computer Science 2023-08-22 Hao Lu , Austin M. Bray , Chao Hu , Andrew T. Zimmerman , Hongyi Xu

With machine learning models being increasingly used to aid decision making even in high-stakes domains, there has been a growing interest in developing interpretable models. Although many supposedly interpretable models have been proposed,…

Artificial Intelligence · Computer Science 2021-08-17 Forough Poursabzi-Sangdeh , Daniel G. Goldstein , Jake M. Hofman , Jennifer Wortman Vaughan , Hanna Wallach

As artificial intelligence plays an increasingly important role in our society, there are ethical and moral obligations for both businesses and researchers to ensure that their machine learning models are designed, deployed, and maintained…

Machine Learning · Computer Science 2020-07-07 Shubham Sharma , Jette Henderson , Joydeep Ghosh

Machine learning models are becoming increasingly popular in different types of settings. This is mainly caused by their ability to achieve a level of predictive performance that is hard to match by human experts in this new era of big…

Machine Learning · Computer Science 2021-09-20 Luis Torgo , Paulo Azevedo , Ines Areosa

The widespread adoption of complex machine learning models in high-stakes domains has brought the "black-box" problem to the forefront of responsible AI research. This paper aims at addressing this issue by improving the Explainable…

Machine Learning · Computer Science 2025-12-02 Isara Liyanage , Uthayasanker Thayasivam

The use of machine learning in Healthcare has the potential to improve patient outcomes as well as broaden the reach and affordability of Healthcare. The history of other application areas indicates that strong benchmarks are essential for…

Deep learning is a powerful tool whose applications in quantitative finance are growing every day. Yet, artificial neural networks behave as black boxes and this hinders validation and accountability processes. Being able to interpret the…

Pricing of Securities · Quantitative Finance 2021-04-20 Damiano Brigo , Xiaoshan Huang , Andrea Pallavicini , Haitz Saez de Ocariz Borde

Large language models (LLMs) have shown considerable potential in supporting medical diagnosis. However, their effective integration into clinical workflows is hindered by physicians' difficulties in perceiving and trusting LLM…

Human-Computer Interaction · Computer Science 2026-01-28 Yuansong Xu , Yichao Zhu , Haokai Wang , Yuchen Wu , Yang Ouyang , Hanlu Li , Wenzhe Zhou , Xinyu Liu , Chang Jiang , Quan Li

The recent development of data-driven AI promises to automate medical diagnosis; however, most AI functions as 'black boxes' to physicians with limited computational knowledge. Using medical imaging as a point of departure, we conducted…

Human-Computer Interaction · Computer Science 2020-01-22 Yao Xie , Melody Chen , David Kao , Ge Gao , Xiang 'Anthony' Chen

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

Rising concern for the societal implications of artificial intelligence systems has inspired demands for greater transparency and accountability. However the datasets which empower machine learning are often used, shared and re-used with…

The use of deep learning in computer vision tasks such as image classification has led to a rapid increase in the performance of such systems. Due to this substantial increment in the utility of these systems, the use of artificial…

Image and Video Processing · Electrical Eng. & Systems 2023-04-05 Vinay Jogani , Joy Purohit , Ishaan Shivhare , Seema C Shrawne

Causal machine learning tools are beginning to see use in real-world policy evaluation tasks to flexibly estimate treatment effects. One issue with these methods is that the machine learning models used are generally black boxes, i.e.,…

Machine Learning · Computer Science 2024-04-01 Patrick Rehill , Nicholas Biddle

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

Machine learning models are increasingly applied to biomedical data, yet their adoption in high stakes domains remains limited by poor robustness, limited interpretability, and instability of learned features under realistic data…

Machine Learning · Computer Science 2026-02-20 Justyna Andrys-Olek , Paulina Tworek , Luca Gherardini , Mark W. Ruddock , Mary Jo Kurt , Peter Fitzgerald , Jose Sousa