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The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

Machine Learning · Computer Science 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

A major requirement for credit scoring models is to provide a maximally accurate risk prediction. Additionally, regulators demand these models to be transparent and auditable. Thus, in credit scoring, very simple predictive models such as…

Machine Learning · Statistics 2020-09-30 Michael Bücker , Gero Szepannek , Alicja Gosiewska , Przemyslaw Biecek

The widespread use of machine learning in credit scoring has brought significant advancements in risk assessment and decision-making. However, it has also raised concerns about potential biases, discrimination, and lack of transparency in…

Machine learning is expected to fuel significant improvements in medical care. To ensure that fundamental principles such as beneficence, respect for human autonomy, prevention of harm, justice, privacy, and transparency are respected,…

In science and medicine, model interpretations may be reported as discoveries of natural phenomena or used to guide patient treatments. In such high-stakes tasks, false discoveries may lead investigators astray. These applications would…

Machine Learning · Statistics 2020-08-18 Collin Burns , Jesse Thomason , Wesley Tansey

Machine learning (ML), artificial intelligence (AI) and other modern statistical methods are providing new opportunities to operationalize previously untapped and rapidly growing sources of data for patient benefit. Whilst there is a lot of…

Although deep learning models are powerful among various applications, most deep learning models are still a black box, lacking verifiability and interpretability, which means the decision-making process that human beings cannot understand.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Qianmengke Zhao , Ye Wang , Qun Liu

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Many safety failures in machine learning arise when models are used to assign predictions to people (often in settings like lending, hiring, or content moderation) without accounting for how individuals can change their inputs. In this…

Machine Learning · Computer Science 2025-07-04 Seung Hyun Cheon , Meredith Stewart , Bogdan Kulynych , Tsui-Wei Weng , Berk Ustun

Explainable Artificial Intelligence (XAI) is an emerging research topic of machine learning aimed at unboxing how AI systems' black-box choices are made. This research field inspects the measures and models involved in decision-making and…

Artificial Intelligence · Computer Science 2021-02-04 Guang Yang , Qinghao Ye , Jun Xia

As machine learning is increasingly deployed in high-stakes contexts affecting people's livelihoods, there have been growing calls to open the black box and to make machine learning algorithms more explainable. Providing useful explanations…

Computers and Society · Computer Science 2020-07-13 Umang Bhatt , McKane Andrus , Adrian Weller , Alice Xiang

Fully automatic deep learning has become the state-of-the-art technique for many tasks including image acquisition, analysis and interpretation, and for the extraction of clinically useful information for computer-aided detection,…

Machine Learning · Computer Science 2021-05-06 Samuel Budd , Emma C Robinson , Bernhard Kainz

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

Machine Learning · Computer Science 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

While interest in the application of machine learning to improve healthcare has grown tremendously in recent years, a number of barriers prevent deployment in medical practice. A notable concern is the potential to exacerbate entrenched…

Machine Learning · Computer Science 2022-05-19 Isabel Chien , Nina Deliu , Richard E. Turner , Adrian Weller , Sofia S. Villar , Niki Kilbertus

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose rising prevalence places increasing demands on a lengthy diagnostic process. Machine learning (ML) has shown promise in automating ASD diagnosis, but most…

Artificial Intelligence · Computer Science 2025-12-09 Gondy Leroy , Prakash Bisht , Sai Madhuri Kandula , Nell Maltman , Sydney Rice

Objectives: To evaluate the consequences of the framing of machine learning risk prediction models. We evaluate how framing affects model performance and model learning in four different approaches previously applied in published…

Well-designed medical decision support system (DSS) have been shown to improve health care quality. However, before they can be used in real clinical situations, these systems must be extensively tested, to ensure that they conform to the…

Artificial Intelligence · Computer Science 2013-12-04 Jean-Baptiste Lamy , Anis Ellini , Vahid Ebrahiminia , Jean-Daniel Zucker , Hector Falcoff , Alain Venot

In the last years many accurate decision support systems have been constructed as black boxes, that is as systems that hide their internal logic to the user. This lack of explanation constitutes both a practical and an ethical issue. The…

Computers and Society · Computer Science 2018-06-22 Riccardo Guidotti , Anna Monreale , Salvatore Ruggieri , Franco Turini , Dino Pedreschi , Fosca Giannotti

Black box machine learning models are currently being used for high stakes decision-making throughout society, causing problems throughout healthcare, criminal justice, and in other domains. People have hoped that creating methods for…

Machine Learning · Statistics 2019-09-24 Cynthia Rudin

The remarkable achievements of Artificial Intelligence (AI) algorithms, particularly in Machine Learning (ML) and Deep Learning (DL), have fueled their extensive deployment across multiple sectors, including Software Engineering (SE).…

Software Engineering · Computer Science 2025-02-06 Sicong Cao , Xiaobing Sun , Ratnadira Widyasari , David Lo , Xiaoxue Wu , Lili Bo , Jiale Zhang , Bin Li , Wei Liu , Di Wu , Yixin Chen
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