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Physical activity and sleep play a major role in the prevention and management of many chronic conditions. It is not a trivial task to understand their impact on chronic conditions. Currently, data from electronic health records (EHRs),…

Machine Learning · Computer Science 2017-12-29 Karan Aggarwal , Shafiq Joty , Luis F. Luque , Jaideep Srivastava

Early prediction of mortality and length of stay(LOS) of a patient is vital for saving a patient's life and management of hospital resources. Availability of electronic health records(EHR) makes a huge impact on the healthcare domain and…

Machine Learning · Computer Science 2020-12-01 Batuhan Bardak , Mehmet Tan

The inherent multimodality and heterogeneous temporal structures of medical data pose significant challenges for modeling. We propose MedM2T, a time-aware multimodal framework designed to address these complexities. MedM2T integrates: (i)…

Machine Learning · Computer Science 2026-03-26 Yu-Chen Kuo , Yi-Ju Tseng

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Electronic Health Records (EHR) contain valuable clinical information for predicting patient outcomes and guiding healthcare decisions. However, effectively modeling Electronic Health Records (EHRs) requires addressing data heterogeneity…

Machine Learning · Computer Science 2025-07-22 Junhan Yu , Zhunyi Feng , Junwei Lu , Tianxi Cai , Doudou Zhou

While the standard network description of complex systems is based on quantifying links between pairs of system units, higher-order interactions (HOIs) involving three or more units play a major role in governing the collective network…

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

There is a great need for technologies that can predict the mortality of patients in intensive care units with both high accuracy and accountability. We present joint end-to-end neural network architectures that combine long short-term…

Computation and Language · Computer Science 2017-09-12 Yohan Jo , Lisa Lee , Shruti Palaskar

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

We developed and validated TRisk, a Transformer-based AI model predicting 36-month mortality in heart failure patients by analysing temporal patient journeys from UK electronic health records (EHR). Our study included 403,534 heart failure…

Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

The recent release of large-scale healthcare datasets has greatly propelled the research of data-driven deep learning models for healthcare applications. However, due to the nature of such deep black-boxed models, concerns about…

Machine Learning · Computer Science 2021-02-16 Chuizheng Meng , Loc Trinh , Nan Xu , Yan Liu

The development of respiratory failure is common among patients in intensive care units (ICU). Large data quantities from ICU patient monitoring systems make timely and comprehensive analysis by clinicians difficult but are ideal for…

Machine Learning · Computer Science 2021-05-13 Matthias Hüser , Martin Faltys , Xinrui Lyu , Chris Barber , Stephanie L. Hyland , Tobias M. Merz , Gunnar Rätsch

Understanding deep learning model behavior is critical to accepting machine learning-based decision support systems in the medical community. Previous research has shown that jointly using clinical notes with electronic health record (EHR)…

Machine Learning · Computer Science 2022-12-07 Severin Husmann , Hugo Yèche , Gunnar Rätsch , Rita Kuznetsova

Wearable systems provide continuous health monitoring and can lead to early detection of potential health issues. However, the lifecycle of wearable systems faces several challenges. First, effective model training for new wearable devices…

In clinical studies, the illness-death model is often used to describe disease progression. A subject starts disease-free, may develop the disease and then die, or die directly. In clinical practice, disease can only be diagnosed at…

Methodology · Statistics 2026-02-02 Marta Spreafico , Anja J. Rueten-Budde , Hein Putter , Marta Fiocco

Patients with chronic obstructive pulmonary disease (COPD) have an increased risk of hospitalizations, strongly associated with decreased survival, yet predicting the timing of these events remains challenging and has received limited…

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

Machine Learning · Computer Science 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez