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Patient time series classification faces challenges in high degrees of dimensionality and missingness. In light of patient similarity theory, this study explores effective temporal feature engineering and reduction, missing value…

Artificial Intelligence · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

Accurate Intensive Care Unit (ICU) outcome prediction is critical for improving patient treatment quality and ICU resource allocation. Existing research mainly focuses on structured data, e.g. demographics and vital signs, and lacks…

Information Theory · Computer Science 2025-02-26 Yucheng Ruan , Daniel J. Tan , See Kiong Ng , Ling Huang , Mengling Feng

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

Machine Learning · Computer Science 2020-03-06 Jacob Deasy , Ari Ercole , Pietro Liò

Electronic Health Records (EHR) have been heavily used in modern healthcare systems for recording patients' admission information to hospitals. Many data-driven approaches employ temporal features in EHR for predicting specific diseases,…

Machine Learning · Computer Science 2021-12-07 Chang Lu , Chandan K. Reddy , Yue Ning

Although increasingly used as a data resource for assembling cohorts, electronic health records (EHRs) pose many analytic challenges. In particular, a patient's health status influences when and what data are recorded, generating sampling…

Methodology · Statistics 2020-04-28 Yifei Sun , Charles E. McCulloch , Kieren A. Marr , Chiung-Yu Huang

Supervised learning with irregularly sampled time series have been a challenge to Machine Learning methods due to the obstacle of dealing with irregular time intervals. Some papers introduced recently recurrent neural network models that…

Machine Learning · Computer Science 2020-03-23 Rafael T. Sousa , Lucas A. Pereira , Anderson S. Soares

The recent success of machine learning methods applied to time series collected from Intensive Care Units (ICU) exposes the lack of standardized machine learning benchmarks for developing and comparing such methods. While raw datasets, such…

Machine Learning · Computer Science 2022-01-19 Hugo Yèche , Rita Kuznetsova , Marc Zimmermann , Matthias Hüser , Xinrui Lyu , Martin Faltys , Gunnar Rätsch

Electronic Health Record (EHR) data can be represented as discrete counts over a high dimensional set of possible procedures, diagnoses, and medications. Supervised topic models present an attractive option for incorporating EHR data as…

Machine Learning · Computer Science 2019-11-21 Jason Ren , Russell Kunes , Finale Doshi-Velez

Availability of diagnostic codes in Electronic Health Records (EHRs) is crucial for patient care as well as reimbursement purposes. However, entering them in the EHR is tedious, and some clinical codes may be overlooked. Given an…

Machine Learning · Computer Science 2023-05-10 Tsvetan R. Yordanov , Ameen Abu-Hanna , Anita CJ Ravelli , Iacopo Vagliano

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

Machine Learning · Computer Science 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

Electronic Health Records (EHRs) contain a wealth of patient data; however, the sparsity of EHRs data often presents significant challenges for predictive modeling. Conventional imputation methods inadequately distinguish between real and…

Machine Learning · Computer Science 2025-02-27 Yinghao Zhu , Zixiang Wang , Long He , Shiyun Xie , Xiaochen Zheng , Liantao Ma , Chengwei Pan

Machine-assisted treatment recommendations hold a promise to reduce physician time and decision errors. We formulate the task as a sequence-to-sequence prediction model that takes the entire time-ordered medical history as input, and…

Machine Learning · Computer Science 2018-02-13 Hung Le , Truyen Tran , Svetha Venkatesh

Electronic records contain sequences of events, some of which take place all at once in a single visit, and others that are dispersed over multiple visits, each with a different timestamp. We postulate that fine temporal detail, e.g.,…

Machine Learning · Computer Science 2019-04-30 Mohammad Taha Bahadori , Zachary Chase Lipton

Hypertension is a major risk factor for stroke, cardiovascular disease, and end-stage renal disease, and its prevalence is expected to rise dramatically. Effective hypertension management is thus critical. A particular priority is…

Computers and Society · Computer Science 2019-07-02 Ramin Mohammadi , Sarthak Jain , Stephen Agboola , Ramya Palacholla , Sagar Kamarthi , Byron C. Wallace

This study is a technical supplement to "AI gone astray: How subtle shifts in patient data send popular algorithms reeling, undermining patient safety." from STAT News, which investigates the effect of time drift on clinically deployed…

Machine Learning · Computer Science 2022-03-31 Janice Yang , Ludvig Karstens , Casey Ross , Adam Yala

Electronic health records contain valuable information for monitoring patients' health trajectories over time. Disease progression models have been developed to understand the underlying patterns and dynamics of diseases using these data as…

Functional magnetic resonance imaging or functional MRI (fMRI) is a very popular tool used for differing brain regions by measuring brain activity. It is affected by physiological noise, such as head and brain movement in the scanner from…

Methodology · Statistics 2023-10-30 Fangyijie Wang , Michael Salter-Townshend

Stability in clinical prediction models is crucial for transferability between studies, yet has received little attention. The problem is paramount in high dimensional data which invites sparse models with feature selection capability. We…

Machine Learning · Statistics 2014-07-24 Shivapratap Gopakumar , Truyen Tran , Dinh Phung , Svetha Venkatesh

Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar