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Determining important vertices in large graphs (e.g., Google's PageRank in the case of the graph of the World Wide Web) facilitated the construction of excellent web search engines, returning the most important hits corresponding to the…

Neurons and Cognition · Quantitative Biology 2021-07-06 Laszlo Keresztes , Evelin Szogi , Balint Varga , Vince Grolmusz

Brain structural connectivity, capturing the white matter fiber tracts among brain regions inferred by diffusion MRI (dMRI), provides a unique characterization of brain anatomical organization. One fundamental question to address with…

Neurons and Cognition · Quantitative Biology 2023-04-05 Selena Wang , Yiting Wang , Frederick H. Xu , Li Shen , Yize Zhao

The architecture of the human connectome supports efficient communication protocols relying either on distances between brain regions or on the intensities of connections. However, none of these protocols combines information about the two…

Neurons and Cognition · Quantitative Biology 2024-10-07 Laia Barjuan , Jordi Soriano , M. Ángeles Serrano

The contribution of structural connectivity to functional brain states remains poorly understood. We present a mathematical and computational study suited to assess the structure--function issue, treating a system of Jansen--Rit neural-mass…

Neurons and Cognition · Quantitative Biology 2020-07-10 Michael Forrester , Stephen Coombes , Jonathan J. Crofts , Stamatios N. Sotiropoulos , Reuben D. O'Dea

Brain connectomes offer detailed maps of neural connections within the brain. Recent studies have proposed novel connectome graph datasets and attempted to improve connectome classification by using graph deep learning. With recent advances…

Machine Learning · Computer Science 2025-03-21 Jose Lara-Rangel , Clare Heinbaugh

The connectional brain template (CBT) captures the shared traits across all individuals of a given population of brain connectomes, thereby acting as a fingerprint. Estimating a CBT from a population where brain graphs are derived from…

Neurons and Cognition · Quantitative Biology 2022-09-28 Ece Cinar , Sinem Elif Haseki , Alaa Bessadok , Islem Rekik

Here we show a method of directing the edges of the connectomes, prepared from diffusion tensor imaging (DTI) datasets from the human brain. Before the present work, no high-definition directed braingraphs (or connectomes) were published,…

Neurons and Cognition · Quantitative Biology 2016-09-29 Balázs Szalkai , Csaba Kerepesi , Bálint Varga , Vince Grolmusz

Connectomes are spatially embedded networks whose architecture has been shaped by physical constraints and communication needs throughout evolution. Using a decentralized navigation protocol, we investigate the relationship between the…

Neurons and Cognition · Quantitative Biology 2020-02-07 Antoine Allard , M. Ángeles Serrano

The brain's intricate connectome, a blueprint for its function, presents immense complexity, yet it arises from a compact genetic code, hinting at underlying low-dimensional organizational principles. This work bridges connectomics and…

Artificial Intelligence · Computer Science 2025-05-28 Yubin Li , Xingyu Liu , Guozhang Chen

The brain's structural connectome supports signal propagation between neuronal elements, shaping diverse coactivation patterns that can be captured as functional connectivity. While the link between structure and function remains an ongoing…

Neurons and Cognition · Quantitative Biology 2022-07-11 Yaqian Yang , Zhiming Zheng , Longzhao Liu , Hongwei Zheng , Yi Zhen , Yi Zheng , Xin Wang , Shaoting Tang

The study of random networks in a neuroscientific context has developed extensively over the last couple of decades. By contrast, techniques for the statistical analysis of these networks are less developed. In this paper, we focus on the…

Neurons and Cognition · Quantitative Biology 2017-07-11 Daniel Fraiman , Ricardo Fraiman

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Divergent brain connectivity is thought to underlie the behavioral and cognitive symptoms observed in many neurodevelopmental disorders. Quantifying divergence from neurotypical connectivity patterns offers a promising pathway to inform…

Neurons and Cognition · Quantitative Biology 2024-11-19 Rui Sherry Shen , Yusuf Osmanlıoğlu , Drew Parker , Darien Aunapu , Benjamin E. Yerys , Birkan Tunç , Ragini Verma

The connectomes of different human brains are pairwise distinct: we cannot talk about an abstract "graph of the brain". Two typical connectomes, however, have quite a few common graph edges that may describe the same connections between the…

Neurons and Cognition · Quantitative Biology 2015-01-07 Balazs Szalkai , Csaba Kerepesi , Balint Varga , Vince Grolmusz

In the face of the stupefying complexity of the human brain, network analysis is a most useful tool that allows one to greatly simplify the problem, typically by approximating the billions of neurons comprising the brain by means of a…

Neurons and Cognition · Quantitative Biology 2023-10-03 Youssef Kora , Christoph Simon

Brain networks are typically represented by adjacency matrices, where each node corresponds to a brain region. In traditional brain network analysis, nodes are assumed to be matched across individuals, but the methods used for node matching…

Methodology · Statistics 2025-03-21 Martin Cole , Yang Xiang , Will Consagra , Anuj Srivastava , Xing Qiu , Zhengwu Zhang

Functional MRI (fMRI) and diffusion MRI (dMRI) are non-invasive imaging modalities that allow in-vivo analysis of a patient's brain network (known as a connectome). Use of these technologies has enabled faster and better diagnoses and…

Machine Learning · Computer Science 2016-12-06 Colin J Brown , Ghassan Hamarneh

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

Neurons and Cognition · Quantitative Biology 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

Structural connectivity in the brain is typically studied by reducing its observation to a single spatial resolution. However, the brain possesses a rich architecture organized over multiple scales linked to one another. We explored the…

Physics and Society · Physics 2020-09-07 Muhua Zheng , Antoine Allard , Patric Hagmann , Yasser Alemán-Gómez , M. Ángeles Serrano

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

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