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Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the…

Applications · Statistics 2018-09-18 Yo Joong Choe , Sivaraman Balakrishnan , Aarti Singh , Jean M. Vettel , Timothy Verstynen

Functional connectivity (FC) as derived from fMRI has emerged as a pivotal tool in elucidating the intricacies of various psychiatric disorders and delineating the neural pathways that underpin cognitive and behavioral dynamics inherent to…

Neurons and Cognition · Quantitative Biology 2024-01-22 Gang Qu , Anton Orlichenko , Junqi Wang , Gemeng Zhang , Li Xiao , Aiying Zhang , Zhengming Ding , Yu-Ping Wang

Signal propagation along the structural connectome of the brain induces changes in the patterns of activity. These activity patterns define global brain states and contain information in accordance with their expected probability of…

Neurons and Cognition · Quantitative Biology 2023-03-16 Leon Weninger , Pragya Srivastava , Dale Zhou , Jason Z. Kim , Eli J. Cornblath , Maxwell A. Bertolero , Ute Habel , Dorit Merhof , Dani S. Bassett

Background: The learning of genotype-phenotype associations and history of human disease by doing detailed and precise analysis of phenotypic abnormalities can be defined as deep phenotyping. To understand and detect this interaction…

Artificial Intelligence · Computer Science 2021-06-04 Rushabh Patel , Yanhui Guo

Estimated connectomes by the means of neuroimaging techniques have enriched our knowledge of the organizational properties of the brain leading to the development of network-based clinical diagnostics. Unfortunately, to date, many of those…

Neurons and Cognition · Quantitative Biology 2018-05-31 Roseric Azondekon , Zachary James Harper , Charles Michael Welzig

As more connectome data become available, the question of how to best analyse the structure of biological neural networks becomes increasingly pertinent. In brain networks, knowing that two areas are connected is often not sufficient, as…

Neurons and Cognition · Quantitative Biology 2024-01-30 Tanguy Fardet , Emmanouil Giannakakis , Lukas Paulun , Anna Levina

This manuscript presents a novel, tightly integrated pipeline for estimating a connectome, which is a comprehensive description of the neural circuits in the brain. The pipeline utilizes magnetic resonance imaging (MRI) data to produce a…

Neurons and Cognition · Quantitative Biology 2011-11-14 William R. Gray , John A. Bogovic , Joshua T. Vogelstein , Bennett A. Landman , Jerry L. Prince , R. Jacob Vogelstein

In recent years, graph-based machine learning techniques, such as reinforcement learning and graph neural networks, have garnered significant attention. While some recent studies have started to explore the relationship between the graph…

Machine Learning · Computer Science 2025-07-15 Yash Arya , Sang Hoon Lee

The difference between the chronological and biological brain age of a subject can be an important biomarker for neurodegenerative diseases, thus brain age estimation can be crucial in clinical settings. One way to incorporate multimodal…

Communication processes within the human brain at different cognitive states are neither well understood nor completely characterized. We assess communication processes in the human connectome using ant colony-inspired cooperative learning…

Neurons and Cognition · Quantitative Biology 2018-02-20 Uttara Tipnis , Enrico Amico , Mario Ventresca , Joaquin Goni

The assessment of brain fingerprints has emerged in the recent years as an important tool to study individual differences and to infer quality of neuroimaging datasets. Studies so far have mainly focused on connectivity fingerprints between…

Neurons and Cognition · Quantitative Biology 2021-01-13 Uttara Tipnis , Kausar Abbas , Elizabeth Tran , Enrico Amico , Li Shen , Alan D. Kaplan , Joaquín Goñi

Aspect-based sentiment analysis aims to determine the sentiment polarity towards a specific aspect in online reviews. Most recent efforts adopt attention-based neural network models to implicitly connect aspects with opinion words. However,…

Computation and Language · Computer Science 2020-04-28 Kai Wang , Weizhou Shen , Yunyi Yang , Xiaojun Quan , Rui Wang

Graph-based learning on functional magnetic resonance imaging (fMRI) has shown strong potential for brain network analysis. However, existing methods degrade under cross-site out-of-distribution (OOD) settings because site-conditioned…

Machine Learning · Computer Science 2026-05-08 Yingxu Wang , Kunyu Zhang , Yanwu Yang , Thomas Wolfers , Yujie Wu , Siyang Gao , Nan Yin

Understanding the dynamic reorganization of brain networks is critical for predicting cognitive decline, neurological progression, and individual variability in clinical outcomes. This work proposes a multimodal graph neural network…

Machine Learning · Computer Science 2026-02-11 Preksha Girish , Rachana Mysore , Kiran K. N. , Hiranmayee R. , Shipra Prashanth , Shrey Kumar

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

The rapid growth of Internet services and mobile devices provides an excellent opportunity to satisfy the strong demand for the personalized item or product recommendation. However, with the tremendous increase of users and items,…

Information Retrieval · Computer Science 2018-12-10 Chen Ma , Peng Kang , Bin Wu , Qinglong Wang , Xue Liu

Recently, growth in our understanding of the computations performed in both biological and artificial neural networks has largely been driven by either low-level mechanistic studies or global normative approaches. However, concrete…

Neurons and Cognition · Quantitative Biology 2023-12-25 Michael Kuoch , Chi-Ning Chou , Nikhil Parthasarathy , Joel Dapello , James J. DiCarlo , Haim Sompolinsky , SueYeon Chung

The correlations of several fundamental properties of human brain connections are investigated in a consensus connectome, constructed from 1064 braingraphs, each on 1015 vertices, corresponding to 1015 anatomical brain areas. The properties…

Neurons and Cognition · Quantitative Biology 2024-04-22 Dániel Hegedűs , Vince Grolmusz

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

Neurons and Cognition · Quantitative Biology 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

Although modern imaging technologies allow us to study connectivity between two distinct brain regions in-vivo, an in-depth understanding of how anatomical structure supports brain function and how spontaneous functional fluctuations emerge…

Neurons and Cognition · Quantitative Biology 2024-10-29 Ziquan Wei , Tingting Dan , Jiaqi Ding , Guorong Wu
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