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One of the central problems in neuroscience is understanding how brain structure relates to function. Naively one can relate the direct connections of white matter fiber tracts between brain regions of interest (ROIs) to the increased…

Neurons and Cognition · Quantitative Biology 2023-08-30 Haoming Yang , Steven Winter , Zhengwu Zhang , David Dunson

Mapping of human brain structural connectomes via diffusion MRI offers a unique opportunity to understand brain structural connectivity and relate it to various human traits, such as cognition. However, head displacement during image…

Neurons and Cognition · Quantitative Biology 2024-09-13 Yizi Zhang , Meimei Liu , Zhengwu Zhang , David Dunson

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

Neural and Evolutionary Computing · Computer Science 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

With distinct advantages in power over behavioral phenotypes, brain imaging traits have become emerging endophenotypes to dissect molecular contributions to behaviors and neuropsychiatric illnesses. Among different imaging features, brain…

Applications · Statistics 2022-12-05 Yize Zhao , Changgee Chang , Jingwen Zhang , Zhengwu Zhang

In order to understand the complex cognitive functions of the human brain, it is essential to study the structural connectome, i.e., the wiring of different brain regions to each other through axonal pathways. However, the high degree of…

Neurons and Cognition · Quantitative Biology 2021-01-25 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Brain structural networks are often represented as discrete adjacency matrices with elements summarizing the connectivity between pairs of regions of interest (ROIs). These ROIs are typically determined a-priori using a brain atlas. The…

Computation · Statistics 2023-08-11 William Consagra , Martin Cole , Xing Qiu , Zhengwu Zhang

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

Applications · Statistics 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

In mapping the human structural connectome, we are in a very fortunate situation: one can compute and compare graphs, describing the cerebral connections between the very same, anatomically identified small regions of the gray matter among…

Neurons and Cognition · Quantitative Biology 2017-12-01 Mate Fellner , Balint Varga , Vince Grolmusz

Auto-encoders have emerged as a successful framework for unsupervised learning. However, conventional auto-encoders are incapable of utilizing explicit relations in structured data. To take advantage of relations in graph-structured data,…

Machine Learning · Computer Science 2019-05-28 Amin Salehi , Hasan Davulcu

Recent advances in neuroimaging along with algorithmic innovations in statistical learning from network data offer a unique pathway to integrate brain structure and function, and thus facilitate revealing some of the brain's organizing…

Signal Processing · Electrical Eng. & Systems 2021-12-21 Yang Li , Gonzalo Mateos , Zhengwu Zhang

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

Machine Learning · Computer Science 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang

Deep graph-theoretic ideas in the context with the graph of the World Wide Web led to the definition of Google's PageRank and the subsequent rise of the most-popular search engine to date. Brain graphs, or connectomes, are being widely…

Neurons and Cognition · Quantitative Biology 2016-02-17 Balazs Szalkai , Balint Varga , Vince Grolmusz

Human braingraphs or connectomes are widely studied in the last decade to understand the structural and functional properties of our brain. In the last several years our research group has computed and deposited thousands of human…

Neurons and Cognition · Quantitative Biology 2024-12-03 Balint Varga , Vince Grolmusz

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

Neurons and Cognition · Quantitative Biology 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

While it is still not possible to describe the neural-level connections of the human brain, we can map the human connectome with several hundred vertices, by the application of diffusion-MRI based techniques. In these graphs, the nodes…

Neurons and Cognition · Quantitative Biology 2020-09-09 Mate Fellner , Balint Varga , Vince Grolmusz

Our understanding of the structure of the brain and its relationships with human traits is largely determined by how we represent the structural connectome. Standard practice divides the brain into regions of interest (ROIs) and represents…

Applications · Statistics 2023-06-13 Rongjie Liu , Meng Li , David B. Dunson

The main goal of this study is to extract a set of brain networks in multiple time-resolutions to analyze the connectivity patterns among the anatomic regions for a given cognitive task. We suggest a deep architecture which learns the…

Machine Learning · Statistics 2017-08-16 Arash Rahnama , Abdullah Alchihabi , Vijay Gupta , Panos Antsaklis , Fatos T. Yarman Vural
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