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Major postoperative complications are devastating to surgical patients. Some of these complications are potentially preventable via early predictions based on intraoperative data. However, intraoperative data comprise long and fine-grained…

Machine Learning · Computer Science 2022-10-11 Dingwen Li , Bing Xue , Christopher King , Bradley Fritz , Michael Avidan , Joanna Abraham , Chenyang Lu

Background: External validations are essential to assess clinical prediction models (CPMs) before deployment. Apart from model misspecification, differences in patient population and other factors influence a model's AUC (c-statistic). We…

Despite the importance of closely monitoring patients in the Intensive Care Unit (ICU), many aspects are still assessed in a limited manner due to the time constraints imposed on healthcare providers. For example, although excessive…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Scott Siegel , Jiaqing Zhang , Sabyasachi Bandyopadhyay , Subhash Nerella , Brandon Silva , Tezcan Baslanti , Azra Bihorac , Parisa Rashidi

Intracerebral hemorrhage (ICH) is a life-risking condition characterized by bleeding within the brain parenchyma. ICU readmission in ICH patients is a critical outcome, reflecting both clinical severity and resource utilization. Accurate…

Machine Learning · Computer Science 2025-01-03 Shuheng Chen , Junyi Fan , Armin Abdollahi , Negin Ashrafi , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Currently, many critical care indices are repetitively assessed and recorded by overburdened nurses, e.g. physical function or facial pain expressions of nonverbal patients. In addition, many essential information on patients and their…

Intensive care unit (ICU) is a crucial hospital department that handles life-threatening cases. Nowadays machine learning (ML) is being leveraged in healthcare ubiquitously. In recent years, management of ICU became one of the most…

Machine Learning · Computer Science 2025-05-26 Alexander Gabitashvili , Philipp Kellmeyer

Forecasting models have been influential in shaping decision-making in the COVID-19 pandemic. However, there is concern that their predictions may have been misleading. Here, we dissect the predictions made by four models for the daily…

Populations and Evolution · Quantitative Biology 2020-08-12 Vincent Chin , Noelle I. Samia , Roman Marchant , Ori Rosen , John P. A. Ioannidis , Martin A. Tanner , Sally Cripps

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

The recent success of machine learning methods applied to time series collected from Intensive Care Units (ICU) exposes the lack of standardized machine learning benchmarks for developing and comparing such methods. While raw datasets, such…

Machine Learning · Computer Science 2022-01-19 Hugo Yèche , Rita Kuznetsova , Marc Zimmermann , Matthias Hüser , Xinrui Lyu , Martin Faltys , Gunnar Rätsch

The COVID-19 pandemic has posed a heavy burden to the healthcare system worldwide and caused huge social disruption and economic loss. Many deep learning models have been proposed to conduct clinical predictive tasks such as mortality…

Machine Learning · Computer Science 2024-01-24 Junyi Gao , Yinghao Zhu , Wenqing Wang , Yasha Wang , Wen Tang , Ewen M. Harrison , Liantao Ma

Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

Computation and Language · Computer Science 2025-08-28 Jun Hou , Lucy Lu Wang

Hyperkalemia is a potentially life-threatening condition that can lead to fatal arrhythmias. Early identification of high risk patients can inform clinical care to mitigate the risk. While hyperkalemia is often a complication of acute…

Machine Learning · Computer Science 2021-01-28 Gloria Hyunjung Kwak , Christina Chen , Lowell Ling , Erina Ghosh , Leo Anthony Celi , Pan Hui

Complex deep learning models show high prediction tasks in various clinical prediction tasks but their inherent complexity makes it more challenging to explain model predictions for clinicians and healthcare providers. Existing research on…

Machine Learning · Computer Science 2026-02-06 Sayantan Kumar , Sean C. Yu , Thomas Kannampallil , Zachary Abrams , Andrew Michelson , Philip R. O. Payne

Modern clinical practice increasingly depends on reasoning over heterogeneous, evolving, and incomplete patient data. Although recent advances in multimodal foundation models have improved performance on various clinical tasks, most…

To date, developing a good model for early intensive care unit (ICU) mortality prediction is still challenging. This paper presents a patient based predictive modeling framework (PPMF) to improve the performance of ICU mortality prediction…

Machine Learning · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one…

Machine Learning · Computer Science 2018-12-03 Eli Sherman , Hitinder Gurm , Ulysses Balis , Scott Owens , Jenna Wiens

Clinical practice in intensive care units (ICUs) requires early warnings when a patient's condition is about to deteriorate so that preventive measures can be undertaken. To this end, prediction algorithms have been developed that estimate…

Machine Learning · Computer Science 2021-02-18 Yilmazcan Özyurt , Mathias Kraus , Tobias Hatt , Stefan Feuerriegel

There is no single prevailing theory of pain that explains its origin, qualities, and alleviation. Although many studies have investigated various molecular targets for pain management, few have attempted to examine the etiology or working…

Neurons and Cognition · Quantitative Biology 2020-06-03 Victoria Ashley Lang , Torbjörn Lundh , Max Ortiz-Catalan

Identifying physiological and behavioral markers for mental health conditions is a longstanding challenge in psychiatry. Depression and suicidal ideation, in particular, lack objective biomarkers, with screening and diagnosis primarily…

Objective: Predicting length of stay after elective spine surgery is essential for optimizing patient outcomes and hospital resource use. This systematic review synthesizes computational methods used to predict length of stay in this…

Machine Learning · Computer Science 2026-02-04 Ha Na Cho , Seungmin Jeong , Yawen Guo , Alexander Lopez , Hansen Bow , Kai Zheng