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Design Research Methodology (DRM) supports systematic design research through representations such as Reference Models and Impact Models. However, the practical construction and maintenance of these models often remains manual, requiring…

Software Engineering · Computer Science 2026-05-12 Apala Chakrabarti

AASM guidelines are the result of decades of efforts aiming at standardizing sleep scoring procedure, with the final goal of sharing a worldwide common methodology. The guidelines cover several aspects from the technical/digital…

Epilepsy is a neurological disease characterized by recurrent and spontaneous seizures. It affects approximately 50 million people worldwide. In majority of the cases accurate diagnosis of the disease can be made without using any…

Quantitative Methods · Quantitative Biology 2013-04-05 Roxana A. Stephanescu , R. G. Shivakeshavan , Sachin S. Talathi

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Clinical guidance systems have been widely adopted to help medical staffs to avoid preventable medical errors such as delay in diagnosis, treatment or untended deviations from best practice guidelines. However, because patient condition…

Computers and Society · Computer Science 2016-10-24 Maryam Rahmaniheris , Yu Jiang , Lui Sha

The recent increase in morbidity is primarily due to chronic diseases including Diabetes, Heart disease, Lung cancer, and brain tumours. The results for patients can be improved, and the financial burden on the healthcare system can be…

Machine Learning · Computer Science 2025-02-18 Sri Varsha Mulakala , G. Neeharika , P. Vinay Kumar , A. Bhargava Kiran

Real-time prediction of clinical interventions remains a challenge within intensive care units (ICUs). This task is complicated by data sources that are noisy, sparse, heterogeneous and outcomes that are imbalanced. In this paper, we…

Machine Learning · Computer Science 2017-05-25 Harini Suresh , Nathan Hunt , Alistair Johnson , Leo Anthony Celi , Peter Szolovits , Marzyeh Ghassemi

Large amounts of electronic medical records collected by hospitals across the developed world offer unprecedented possibilities for knowledge discovery using computer based data mining and machine learning. Notwithstanding significant…

Quantitative Methods · Quantitative Biology 2016-07-27 Ieva Vasiljeva , Ognjen Arandjelovic

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…

Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and…

Artificial Intelligence · Computer Science 2026-04-28 Aaryan Shah , Andrew Hines , Alexia Downs , Denis Bajet , Paulius Mui , Fabiano Araujo , Laura Offutt , Aida Rutledge , Elizabeth Jimenez

Cognitive diagnosis has been developed for decades as an effective measurement tool to evaluate human cognitive status such as ability level and knowledge mastery. It has been applied to a wide range of fields including education, sport,…

Artificial Intelligence · Computer Science 2024-07-09 Fei Wang , Weibo Gao , Qi Liu , Jiatong Li , Guanhao Zhao , Zheng Zhang , Zhenya Huang , Mengxiao Zhu , Shijin Wang , Wei Tong , Enhong Chen

Monitoring the health status of patients in the Intensive Care Unit (ICU) is a critical aspect of providing superior care and treatment. The availability of large-scale electronic health records (EHR) provides machine learning models with…

Artificial Intelligence · Computer Science 2023-05-05 Jun Wu , Xuesong Ye , Chengjie Mou , Weinan Dai

With the increase of the Electronic Health Records (EHR) data, more and more researchers are developing machine learning models to learn from the medical notes. These unstructured text data pose significant challenges on the learning…

Machine Learning · Computer Science 2026-05-06 Zijiang Yang

Purpose: Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-10 Siddharth Agarwal , David A. Wood , Mariusz Grzeda , Chandhini Suresh , Munaib Din , James Cole , Marc Modat , Thomas C Booth

Particle-in-Cell (PIC) approach for modeling dense granular flows has gained popularity in recent years due to its time to solution efficiency. The methodology is useful for modeling large-scale systems with a relatively lower computational…

Fluid Dynamics · Physics 2023-05-03 Aytekin Gel , Avinash Vaidheeswaran , Mary Ann Clarke

We propose a network architecture capable of reliably estimating uncertainty of regression based predictions without sacrificing accuracy. The current state-of-the-art uncertainty algorithms either fall short of achieving prediction…

Machine Learning · Computer Science 2022-02-22 Kinjal Patel , Steven Waslander

The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

Quantitative Methods · Quantitative Biology 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

Machine Learning · Computer Science 2019-03-07 Avijit Mitra , Khalid Ashraf

In the context of clinical research, computational models have received increasing attention over the past decades. In this systematic review, we aimed to provide an overview of the role of so-called in silico clinical trials (ISCTs) in…

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