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In the presence of ATP, molecular motors generate active force dipoles that drive suspensions of protein filaments far from thermodynamic equilibrium, leading to exotic dynamics and pattern formation. Microscopic modelling can help to…

Biological Physics · Physics 2015-06-17 D. A. Head , W. J. Briels , G. Gompper

Biological cells in soft materials can be modeled as anisotropic force contraction dipoles. The corresponding elastic interaction potentials are long-ranged ($\sim 1/r^3$ with distance $r$) and depend sensitively on elastic constants,…

Soft Condensed Matter · Physics 2009-11-07 U. S. Schwarz , S. A. Safran

Cellular tissue behavior is a multiscale problem. At the cell level, out of equilibrium, biochemical reactions drive physical cell-cell interactions in a typical active matter process. Cell modeling computer simulations are a robust tool to…

Soft Condensed Matter · Physics 2021-02-09 Emanuel F. Teixeira , Heitor C. M. Fernandes , Leonardo G. Brunnet

With the help of molecular dynamics simulations we study an ensemble of active dumbbells in purely repulsive interaction. We derive the phase diagram in the density-activity plane and we characterise the various phases with liquid, hexatic…

Statistical Mechanics · Physics 2018-12-21 Isabella Petrelli , Pasquale Digregorio , Leticia F. Cugliandolo , Giuseppe Gonnella , Antonio Suma

We show from experiments and simulations on vibration-activated granular matter that self-propelled polar rods in an elastic medium on a substrate turn and move towards each other. We account for this effective attraction through a…

Soft Condensed Matter · Physics 2022-06-08 Rahul Kumar Gupta , Raushan Kant , Harsh Soni , A. K. Sood , Sriram Ramaswamy

Anchorage-dependent cells collect information on the mechanical properties of the environment through their contractile machineries and use this information to position and orient themselves. Since the probing process is anisotropic,…

Soft Condensed Matter · Physics 2007-05-23 I. B. Bischofs , S. A. Safran , U. S. Schwarz

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

Cell Behavior · Quantitative Biology 2016-06-29 Davide Ambrosi , Anna Zanzottera

Active matter agents consume internal energy or extract energy from the environment for locomotion and force generation. Already rather generic models, such as ensembles of active Brownian particles, exhibit phenomena, which are absent at…

Soft Condensed Matter · Physics 2020-07-27 Roland G. Winkler , Gerhard Gompper

Fluid-structure interactions between active and passive components are important for many biological systems to function. A particular example is chromatin in the cell nucleus, where ATP-powered processes drive coherent motions of the…

Soft Condensed Matter · Physics 2024-02-15 Scott Weady , David B. Stein , Alexandra Zidovska , Michael J. Shelley

We derive an analytic expression for the distribution of velocities of multiple interacting active particles which we test by numerical simulations. In clear contrast with equilibrium we find that the velocities are coupled to positions.…

We study theoretically the phase diagram of compressible active polar gels such as the actin network of eukaryotic cells. Using generalized hydrodynamics equations, we perform a linear stability analysis of the uniform states in the case of…

Soft Condensed Matter · Physics 2009-11-13 R. Voituriez , J. F. Joanny , J. Prost

Active gels made of cytoskeletal proteins are valuable materials with attractive non-equilibrium properties such as spatial self-organization and self-propulsion. At least four typical routes to spatial patterning have been reported to date…

We study analytically and numerically a generic continuum model of an isotropic active solid with internal stresses generated by non-equilibrium `active' mechano-chemical reactions. Our analysis shows that the gel can be tuned through three…

Soft Condensed Matter · Physics 2015-05-30 Shiladitya Banerjee , Tanniemola B. Liverpool , M. Cristina Marchetti

Active gels play an important role in biology and in inspiring biomimetic active materials, due to their ability to change shape, size and create their own morphology; the relevant mechanics behind these changes is driven by…

Soft Condensed Matter · Physics 2023-09-22 Anne Bernheim-Groswasser , Gefen Livne , Paola Nardinocchi , Filippo Recrosi , Luciano Teresi

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

Soft Condensed Matter · Physics 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

Systems of active particles can show a large variety of collective behavior. In theory, two aspects determine the collective behavior: the model at the particle level and the parameter regime. While many studies consider a single model and…

Soft Condensed Matter · Physics 2025-11-17 Colin-Marius Koch , Michael Wilczek

A milestone of phase separation kinetics is the emergence of universal power laws $\sim t^{1/z}$ governing the domain growth evolution. We investigate a phase-separating polar active model comprising a scalar density field with an advective…

Soft Condensed Matter · Physics 2025-08-20 Massimiliano Semeraro , Leticia F. Cugliandolo , Giuseppe Gonnella , Adriano Tiribocchi

In this study, we investigate the behaviors and dynamics of self-propelled particles with active reorientation (AR) in a double-well potential. We explore the competition between AR and external potentials, revealing that self-propelled…

Soft Condensed Matter · Physics 2026-01-26 Lu Chen , Baopi Liu , Ning Liu

Continuum models of active nematic gels have proved successful to describe a number of biological systems consisting of a population of rodlike motile subunits in a fluid environment. However, in order to get a thorough understanding of the…

Soft Condensed Matter · Physics 2023-05-03 Stefano Turzi

The transport of active particles may occur in complex environments, in which it emerges from the interplay between the mobility of the active components and the quenched disorder of the environment. Here we explore structural and dynamical…

Soft Condensed Matter · Physics 2023-03-31 Fergus J. Moore , John Russo Tanniemola B. Liverpool , C. Patrick Royall