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This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…

Fluid Dynamics · Physics 2021-01-27 Georgios Bletsos , Niklas Kühl , Thomas Rung

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

Designing distributed optimal controllers subject to communication constraints is a difficult problem unless structural assumptions are imposed on the underlying dynamics and information exchange structure, e.g., sparsity, delay, or spatial…

Systems and Control · Electrical Eng. & Systems 2022-10-31 Fengjun Yang , Fernando Gama , Somayeh Sojoudi , Nikolai Matni

In this work, we focus on the Partial Constraint Satisfaction Problem (PCSP) over control-flow graphs (CFGs) of programs. PCSP serves as a generalization of the well-known Constraint Satisfaction Problem (CSP). In the CSP framework, we…

Computation and Language · Computer Science 2026-02-04 Xuran Cai , Amir Goharshady

In this paper, we study the problem of traffic management in highways facing stochastic perturbations. To model the macroscopic traffic flow under perturbations, we use cell-transmission model with Markovian capacities. The decision…

Systems and Control · Computer Science 2019-07-04 Li Jin , Alexander A. Kurzhanskiy , Saurabh Amin

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

The scarcity of high-quality imaging data for coronary angiography (CAG) stenosis limits the clinical translation of automated stenosis detection. Synthetic stenosis data provides a practical avenue to augment training sets, improving data…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Jialin Li , Zhuo Zhang , Yue Cao , Guipeng Lan , Jiabao Wen , Shuai Xiao , Jiachen Yang

The immersed boundary (IB) method is a mathematical and numerical framework for problems of fluid-structure interaction, treating the particular case in which an elastic structure is immersed in a viscous incompressible fluid. The IB…

Computational Engineering, Finance, and Science · Computer Science 2017-03-29 Boyce E. Griffith

In this work we deal with the optimal design and optimal control of structures undergoing large rotations. In other words, we show how to find the corresponding initial configuration and the corresponding set of multiple load parameters in…

Neural and Evolutionary Computing · Computer Science 2009-02-10 A. Ibrahimbegovic , C. Knopf-Lenoir , A. Kucerova , P. Villon

Several cardiovascular diseases are caused from localised abnormal blood flow such as in the case of stenosis or aneurysms. Prevailing theories propose that the development is caused by abnormal wall-shear stress in focused areas.…

Optimization and Control · Mathematics 2016-07-12 S. W. Funke , M. Nordaas , Øyvind Evju , M. S. Alnæs , K. -A. Mardal

Accurate prediction of cerebral blood flow is essential for the diagnosis and treatment of cerebrovascular diseases. Traditional computational methods, however, often incur significant computational costs, limiting their practicality in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Seungyeon Kim , Wheesung Lee , Sung-Ho Ahn , Do-Eun Lee , Tae-Rin Lee

In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…

Medical Physics · Physics 2021-04-07 Pepe Eulzer , Monique Meuschke , Carsten Klingner , Kai Lawonn

We present an $m^{4/3+o(1)}\log W$-time algorithm for solving the minimum cost flow problem in graphs with unit capacity, where $W$ is the maximum absolute value of any edge weight. For sparse graphs, this improves over the best known…

Data Structures and Algorithms · Computer Science 2020-04-10 Kyriakos Axiotis , Aleksander Mądry , Adrian Vladu

To be applicable to real world scenarios trajectory planning schemes for mobile autonomous systems must be able to efficiently deal with obstacles in the area of operation. In the context of optimization based trajectory planning and…

Optimization and Control · Mathematics 2021-04-27 Max Lutz , Thomas Meurer

In this paper, we introduce dynamics factor graphs as a graphical framework to solve dynamics problems and kinodynamic motion planning problems with full consideration of whole-body dynamics and contacts. A factor graph representation of…

Robotics · Computer Science 2020-11-13 Mandy Xie , Alejandro Escontrela , Frank Dellaert

Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible…

Tissues and Organs · Quantitative Biology 2024-05-06 Charles Puelz , Craig G. Rusin , Dan Lior , Shagun Sachdeva , Tam T. Doan , Lindsay F. Eilers , Dana Reaves-O'Neal , Silvana Molossi

This paper presents a novel distributed approach for solving AC power flow (PF) problems. The optimization problem is reformulated into a distributed form using a communication structure corresponding to a hypergraph, by which complex…

Optimization and Control · Mathematics 2024-07-03 Xinliang Dai , Yingzhao Lian , Yuning Jiang , Colin N. Jones , Veit Hagenmeyer

This paper presents a unique solution to challenges in medical image processing by incorporating an adaptive curve grey wolf optimization (ACGWO) algorithm into neural network backpropagation. Neural networks show potential in medical data…

Machine Learning · Computer Science 2024-12-24 Sihan Niu , Yifan Zhou , Zhikai Li , Shuyao Huang , Yujun Zhou

Quantitative photoacoustic computed tomography (qPACT) is an emerging medical imaging modality that carries the promise of high-contrast, fine-resolution imaging of clinically relevant quantities like hemoglobin concentration and…

Medical Physics · Physics 2024-10-15 Evan Scope Crafts , Mark A. Anastasio , Umberto Villa

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…