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In several problems involving fluid flows, Computational Fluid Dynamics (CFD) provides detailed quantitative information, and often allows the designer to successfully optimize the system, by minimizing a cost function. Sometimes, however,…

The computation of time-optimal velocity profiles along prescribed paths, subject to generic acceleration constraints, is a crucial problem in robot trajectory planning, with particular relevance to autonomous racing. However, the existing…

Robotics · Computer Science 2026-01-08 Mattia Piazza , Mattia Piccinini , Sebastiano Taddei , Francesco Biral , Enrico Bertolazzi

This paper addresses the challenge of generating optimal vehicle flow at the macroscopic level. Although several studies have focused on optimizing vehicle flow, little attention has been given to ensuring it can be practically achieved. To…

Optimization and Control · Mathematics 2023-09-08 Heeseung Bang , Andreas A. Malikopoulos

The purpose of this paper is to address a class of hybrid optimal control problems constrained with hyperelasticity and constant global volume. This type of problems can intervene for example in the mechanical aspects of cardiac activity.…

Optimization and Control · Mathematics 2024-09-06 Sébastien Court

Daily or weekly cone-beam computed tomography (CBCT) is employed in image-guided radiotherapy (IGRT) for precise patient alignment. However, its clinical utility in quantitative tasks is hindered by severe artifacts and inaccurate Hounsfeld…

Medical Physics · Physics 2026-03-09 Junbo Peng , Huiqiao Xie , Tonghe Wang , Xiangyang Tang , Xiaofeng Yang

In this paper, we introduce a hierarchical decision-making framework for emerging mobility systems. Despite numerous studies focusing on optimizing vehicle flow, practical feasibility has often been overlooked. To address this gap, we…

Systems and Control · Electrical Eng. & Systems 2023-11-23 Heeseung Bang , Andreas A. Malikopoulos

Quantitative angiography (QA) in two dimensions has been instrumental in assessing neurovascular contrast flow patterns, aiding disease severity and treatment outcome evaluations. However, QA requires high spatio-temporal resolution,…

Flow control has been the subject of numerous experimental and theoretical works. In this numerical study, we analyse full-order, optimal controllers for large dynamical systems in presence of multiple actuators and sensors. We start from…

Fluid Dynamics · Physics 2018-04-18 Onofrio Semeraro , Jan Oscar Pralits

In coronary angiography the condition of myocardial blood supply is assessed by analyzing 2-D X-ray projections of contrasted coronary arteries. This is done using a flexible C-arm system. Due to the X-ray immanent dimensionality reduction…

A novel adjoint-based framework oriented to optimal flow control in compressible direct numerical simulations is presented. Also, a new formulation of the adjoint characteristic boundary conditions is introduced, which enhances the…

Computational Physics · Physics 2016-05-24 J. Javier Otero , Ati S. sharma , Richard D. Sandberg

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment…

The control flow graph (CFG) representation of a procedure used by virtually all flow-sensitive program analyses, admits a large number of infeasible control flow paths i.e., these paths do not occur in any execution of the program. Hence…

Software Engineering · Computer Science 2022-08-29 Komal Pathade , Uday Khedker

The reservoir computing paradigm is employed to classify heartbeat anomalies online based on electrocardiogram signals. Inspired by the principles of information processing in the brain, reservoir computing provides a framework to design,…

Machine Learning · Computer Science 2019-07-24 Fatemeh Hadaeghi

Objective: Deformable image registration is a fundamental problem in medical image analysis, with applications such as longitudinal studies, population modeling, and atlas based image segmentation. Registration is often phrased as an…

Computer Vision and Pattern Recognition · Computer Science 2018-10-22 Simon Ekström , Filip Malmberg , Håkan Ahlström , Joel Kullberg , Robin Strand

3D-0D coupled flow models are widely used across many application fields but remain challenging to solve. Implicit coupling introduces non-local terms, whereas explicit coupling results in only conditionally stable schemes. Furthermore,…

Numerical Analysis · Mathematics 2025-12-10 Jeremías Garay , David Nolte , Cristóbal Bertoglio

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

Deviation of blood flow from an optimal range is known to be associated with the initiation and progression of vascular pathologies. Important open questions remain about how the abnormal flow drives specific wall changes in pathologies…

Applying optimal control algorithms on realistic quantum systems confronts two key challenges: to efficiently adopt physical constraints in the optimization and to minimize the variables for the convenience of experimental tune-ups. In…

Quantum Physics · Physics 2022-02-09 Yao Song , Junning Li , Yong-Ju Hai , Qihao Guo , Xiu-Hao Deng

Multi-modality cardiac imaging plays a key role in the management of patients with cardiovascular diseases. It allows a combination of complementary anatomical, morphological and functional information, increases diagnosis accuracy, and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Lei Li , Wangbin Ding , Liqun Huang , Xiahai Zhuang , Vicente Grau
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