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Nasal breathing difficulties (NBD) are widespread and difficult to diagnose; the failure rate of their surgical corrections is high. Computational Fluid Dynamics (CFD) enables diagnosis of NBD and surgery planning, by comparing a…

Fluid Dynamics · Physics 2023-08-23 Eric Segalerba , Gabriele Dini Ciacci , Maurizio Quadrio , Jan O. Pralits

Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…

Medical Physics · Physics 2011-01-20 Irene Vignon Clementel , Alison L. Marsden , Jeffrey A. Feinstein

This study creates a physiologically realistic virtual patient database (VPD), representing the human arterial system, for the primary purpose of studying the affects of arterial disease on haemodynamics. A low dimensional representation of…

Medical Physics · Physics 2021-08-05 Gareth Jones , Jim Parr , Perumal Nithiarasu , Sanjay Pant

MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but…

Cardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and…

Intraventricular vector flow mapping (iVFM) is a technique for retrieving 2-D velocity vector fields of blood flow in the left ventricle. This method is based on conventional color Doppler imaging, which makes iVFM compatible with the…

The detection of cardiovascular diseases (CVD) using machine learning techniques represents a significant advancement in medical diagnostics, aiming to enhance early detection, accuracy, and efficiency. This study explores a comparative…

Machine Learning · Computer Science 2024-05-28 Dayana K , S. Nandini , Sanjjushri Varshini R

Medical therapy for patients with severe heart disease often relies on left ventricular assist devices (LVADs). It is an ongoing topic of research how complications like stagnation and thrombosis can be prevented by using artificial…

Fluid Dynamics · Physics 2025-03-31 Maximilian R. Schuster , Nico Dirkes , Fabian Key , Stefanie Elgeti , Marek Behr

Color Doppler by transthoracic echocardiography creates 2-D fan-shaped maps of blood velocities in the cardiac cavities. It is a one-component velocimetric technique since it only returns the velocity components parallel to the ultrasound…

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Quantitative Methods · Quantitative Biology 2025-08-27 Julian Suk , Guido Nannini , Patryk Rygiel , Christoph Brune , Gianluca Pontone , Alberto Redaelli , Jelmer M. Wolterink

The four essential chambers of one's heart that lie in the thoracic cavity are crucial for one's survival, yet ironically prove to be the most vulnerable. Cardiovascular disease (CVD) also commonly referred to as heart disease has steadily…

Machine Learning · Computer Science 2021-11-17 Aaditya Surya

Cardiovascular diseases (CVDs) are the number one cause of death worldwide. While there is growing evidence that the atrial fibrillation (AF) has strong associations with various CVDs, this heart arrhythmia is usually diagnosed using…

Systems and Control · Electrical Eng. & Systems 2022-07-13 Wei-Ying Yi , Peng-Fei Liu , Sheung-Lai Lo , Ya-Fen Chan , Yu Zhou , Yee Leung , Kam-Sang Woo , Alex Pui-Wai Lee , Jia-Min Chen , Kwong-Sak Leung

We report computational results of blood flow through a model of the human aortic arch and a vessel of actual diameter and length. On the top of the aortic arch the branching of the %%three arteries are included: the subclavian and jugular.…

Fluid Dynamics · Physics 2008-11-11 Renat A. Sultanov , Dennis Guster

Cardio/cerebrovascular diseases (CVD) have become one of the major health issue in our societies. But recent studies show that the present pathology tests to detect CVD are ineffectual as they do not consider different stages of platelet…

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

Fluid Dynamics · Physics 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni

To address the issue of computational efficiency related to the modelling of blood flow in complex networks, we derive a family of nonlinear lumped-parameter models for blood flow in compliant vessels departing from a well-established…

Numerical Analysis · Mathematics 2022-01-06 Beatrice Ghitti , Eleuterio F. Toro , Lucas O. Müller

Automatic segmentation of left ventricle (LV) myocardium in cardiac short-axis cine MR images acquired on subjects with myocardial infarction is a challenging task, mainly because of the various types of image inhomogeneity caused by the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-16 Dongqing Zhang , Ilknur Icke , Belma Dogdas , Sarayu Parimal , Smita Sampath , Joseph Forbes , Ansuman Bagchi , Chih-Liang Chin , Antong Chen

Cardiovascular disease (CVD) remains the leading cause of death worldwide, requiring urgent development of effective risk assessment methods for timely intervention. While current research has introduced non-invasive and efficient…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Lehan Wang , Hualiang Wang , Chubin Ou , Lushi Chen , Yunyi Liang , Xiaomeng Li

Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…

Biological Physics · Physics 2014-02-27 Suprijadi , Mohamad Rendi , Petrus Subekti , Sparisoma Viridi

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

Tissues and Organs · Quantitative Biology 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu