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We introduce the convex bundle method to solve convex, non-smooth optimization problems on Riemannian manifolds of bounded sectional curvature. Each step of our method is based on a model that involves the convex hull of previously…

Optimization and Control · Mathematics 2025-07-21 Ronny Bergmann , Roland Herzog , Hajg Jasa

Single-molecule atomic force spectroscopy probes elastic properties of titin, ubiquitin and other relevant proteins. We explain bioprotein folding dynamics under both length- and force-clamp by modeling polyprotein modules as particles in a…

Statistical Mechanics · Physics 2016-11-17 L. L. Bonilla , A. Carpio , A. Prados

Optimization methods play a central role in signal processing, serving as the mathematical foundation for inference, estimation, and control. While classical iterative optimization algorithms provide interpretability and theoretical…

Machine Learning · Computer Science 2026-04-01 Nir Shlezinger , Santiago Segarra , Yi Zhang , Dvir Avrahami , Zohar Davidov , Tirza Routtenberg , Yonina C. Eldar

We consider solving linear optimization (LO) problems with uncertain objective coefficients. For such problems, we often employ robust optimization (RO) approaches by introducing an uncertainty set for the unknown coefficients. Typical RO…

Optimization and Control · Mathematics 2023-12-04 Ayaka Ueta , Mirai Tanaka , Ken Kobayashi , Kazuhide Nakata

We introduce Random Projection Flows (RPFs), a principled framework for injective normalizing flows that leverages tools from random matrix theory and the geometry of random projections. RPFs employ random semi-orthogonal matrices, drawn…

Machine Learning · Computer Science 2025-11-26 Ahmad Ayaz Amin , Baha Uddin Kazi

Deep neural networks provide unprecedented performance gains in many real world problems in signal and image processing. Despite these gains, future development and practical deployment of deep networks is hindered by their blackbox nature,…

Image and Video Processing · Electrical Eng. & Systems 2020-08-10 Vishal Monga , Yuelong Li , Yonina C. Eldar

The nonuniform fast Fourier transform (NUFFT) enables spectral methods for problems with irregularly spaced samples, with applications in medical imaging, molecular dynamics, and kinetic plasma simulations. Existing implementations are…

Computational Engineering, Finance, and Science · Computer Science 2026-05-12 Paul Fischill , Andreas Adelmann , Sriramkrishnan Muralikrishnan

This paper provides a unifying view of a wide range of problems of interest in machine learning by framing them as the minimization of functionals defined on the space of probability measures. In particular, we show that generative…

Machine Learning · Computer Science 2019-05-21 Casey Chu , Jose Blanchet , Peter Glynn

Removing various degradations from damaged documents greatly benefits digitization, downstream document analysis, and readability. Previous methods often treat each restoration task independently with dedicated models, leading to a…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Fangmin Zhao , Weichao Zeng , Zhenhang Li , Dongbao Yang , Binbin Li , Xiaojun Bi , Yu Zhou

Unfolding the band structure of a supercell to a normal cell enables us to investigate how symmetry breakers such as surfaces and impurities perturb the band structure of the normal cell. We generalize the unfolding method, originally…

Materials Science · Physics 2013-08-07 Chi-Cheng Lee , Yukiko Yamada-Takamura , Taisuke Ozaki

We present the SLIM (https://github.com/slimgroup) open-source software framework for computational geophysics, and more generally, inverse problems based on the wave-equation (e.g., medical ultrasound). We developed a software environment…

Most signal processing and statistical applications heavily rely on specific data distribution models. The Gaussian distributions, although being the most common choice, are inadequate in most real world scenarios as they fail to account…

Statistics Theory · Mathematics 2023-04-17 Ilya Soloveychik

The prediction of protein stability changes following single-point mutations plays a pivotal role in computational biology, particularly in areas like drug discovery, enzyme reengineering, and genetic disease analysis. Although…

Quantitative Methods · Quantitative Biology 2025-05-01 Ivan Rossi , Guido Barducci , Tiziana Sanavia , Paola Turina , Emidio Capriotti , Piero Fariselli

With the help of force spectroscopy, several analytical theories aim at estimating the rate coefficient of folding for various proteins. Nevertheless, a chief bottleneck lies in the fact that there is still no perfect consensus on how does…

Soft Condensed Matter · Physics 2020-04-30 Aviel Chaimovich , Christian Leitold , Christoph Dellago

A stochastic algorithm is proposed, finding the set of generalized means associated to a probability measure on a compact Riemannian manifold M and a continuous cost function on the product of M by itself. Generalized means include p-means…

Probability · Mathematics 2013-05-28 Marc Arnaudon , Laurent Miclo

In practical optimization problems, we typically model uncertainty as a random variable though its true probability distribution is unobservable to the decision maker. Historical data provides some information of this distribution that we…

Optimization and Control · Mathematics 2025-01-28 Arjun Ramachandra , Napat Rujeerapaiboon , Melvyn Sim

In the era of foundation models, fine-tuning pre-trained models for specific downstream tasks has become crucial. This drives the need for robust fine-tuning methods to address challenges such as model overfitting and sparse labeling.…

Machine Learning · Computer Science 2025-12-12 Shikun Liu , Deyu Zou , Nima Shoghi , Victor Fung , Kai Liu , Pan Li

Most signal processing problems involve the challenging task of multidimensional probability density function (PDF) estimation. In this work, we propose a solution to this problem by using a family of Rotation-based Iterative…

Machine Learning · Statistics 2016-02-02 Valero Laparra , Gustavo Camps-Valls , Jesús Malo

Presentation of folded documents is not an uncommon case in modern society. Digitizing such documents by capturing them with a smartphone camera can be tricky since a crease can divide the document contents into separate planes. To unfold…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 A. M. Ershov , D. V. Tropin , E. E. Limonova , D. P. Nikolaev , V. V. Arlazarov

Non-ideal measurement computed tomography (NICT), which lowers radiation at the cost of image quality, is expanding the clinical use of CT. Although unified models have shown promise in NICT enhancement, most methods require paired data,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Fengzhi Xu , Ziyuan Yang , Zexin Lu , Yingyu Chen , Fenglei Fan , Hongming Shan , Yi Zhang