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Recurrent neural networks (RNNs) are powerful models of sequential data. They have been successfully used in domains such as text and speech. However, RNNs are susceptible to overfitting; regularization is important. In this paper we…

Machine Learning · Statistics 2018-07-16 Adji B. Dieng , Rajesh Ranganath , Jaan Altosaar , David M. Blei

The Normalized Relative Compression (NRC) is a recent dissimilarity measure, related to the Kolmogorov Complexity. It has been successfully used in different applications, like DNA sequences, images or even ECG (electrocardiographic)…

Information Theory · Computer Science 2018-06-04 João M. Carvalho , Susana Brás , Diogo Pratas , Jacqueline Ferreira , Sandra C. Soares , Armando J. Pinho

The combination of Deep Learning techniques and Raman spectroscopy shows great potential offering precise and prompt identification of pathogenic bacteria in clinical settings. However, the traditional closed-set classification approaches…

Quantitative Methods · Quantitative Biology 2023-10-24 Yaroslav Balytskyi , Nataliia Kalashnyk , Inna Hubenko , Alina Balytska , Kelly McNear

Regression analysis-based approaches have been widely studied for face recognition (FR) in the past several years. More recently, to better deal with some difficult conditions such as occlusions and illumination, nuclear norm based matrix…

Numerical Analysis · Mathematics 2020-01-30 Jifei Miao , Kit Ian Kou

Network modeling has become increasingly popular for analyzing genomic data, to aid in the interpretation and discovery of possible mechanistic components and therapeutic targets. However, genomic-scale networks are high-dimensional models…

Computation · Statistics 2017-02-27 Jonatan Kallus , Jose Sanchez , Alexandra Jauhiainen , Sven Nelander , Rebecka Jörnsten

The interpretation of count data originating from the current generation of DNA sequencing platforms requires special attention. In particular, the per-sample library sizes often vary by orders of magnitude from the same sequencing run, and…

Quantitative Methods · Quantitative Biology 2015-06-17 Paul J. McMurdie , Susan Holmes

Recurrent neural networks (RNNs) have been applied to a broad range of applications, including natural language processing, drug discovery, and video recognition. Their vulnerability to input perturbation is also known. Aligning with a view…

Machine Learning · Computer Science 2021-05-14 Wei Huang , Youcheng Sun , Xingyu Zhao , James Sharp , Wenjie Ruan , Jie Meng , Xiaowei Huang

Unlike traditional statistical methods, Conformal Prediction (CP) allows for the determination of valid and accurate confidence levels associated with individual predictions based only on exchangeability of the data. We here introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Marcos López-De-Castro , Alberto García-Galindo , Rubén Armañanzas

This article reviews recent advances in applying natural language processing (NLP) to Electronic Health Records (EHRs) for computational phenotyping. NLP-based computational phenotyping has numerous applications including diagnosis…

Computation and Language · Computer Science 2018-06-18 Zexian Zeng , Yu Deng , Xiaoyu Li , Tristan Naumann , Yuan Luo

While using two-dimensional convolutional neural networks (2D-CNNs) in image processing, it is possible to manipulate domain information using channel statistics, and instance normalization has been a promising way to get domain-invariant…

Sound · Computer Science 2022-06-28 Byeonggeun Kim , Seunghan Yang , Jangho Kim , Hyunsin Park , Juntae Lee , Simyung Chang

Accurate RNA structure modeling remains difficult because RNA backbones are highly flexible, non-canonical interactions are prevalent, and experimentally determined 3D structures are comparatively scarce. We introduce \emph{RiboSphere}, a…

Machine Learning · Computer Science 2026-03-23 Zhou Zhang , Hanqun Cao , Cheng Tan , Fang Wu , Pheng Ann Heng , Tianfan Fu

Detecting occupied subbands is a key task for wireless applications such as unlicensed spectrum access. Recently, detection methods were proposed that extract per-subband features from sub-Nyquist baseband samples and then apply…

Signal Processing · Electrical Eng. & Systems 2024-05-28 Hyojin Lee , Sangwoo Park , Osvaldo Simeone , Yonina C. Eldar , Joonhyuk Kang

In the last decade, the discovery of noncoding RNA(ncRNA) has exploded. Classifying these ncRNA is critical todetermining their function. This thesis proposes a new methodemploying deep convolutional neural networks (CNNs) to classifyncRNA…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Brian McClannahan , Cucong Zhong , Guanghui Wang

Background: Predictive, stable and interpretable gene signatures are generally seen as an important step towards a better personalized medicine. During the last decade various methods have been proposed for that purpose. However, one…

Genomics · Quantitative Biology 2013-05-28 Yupeng Cun , Holger Fröhlich

Although neural networks achieve promising performance in many tasks, they may still fail when encountering some examples and bring about risks to applications. To discover risky samples, previous literature attempts to search for patterns…

Machine Learning · Computer Science 2025-12-23 Han Yu , Hao Zou , Xingxuan Zhang , Zhengyi Wang , Yue He , Kehan Li , Peng Cui

The determination of a patient's DNA sequence can, in principle, reveal an increased risk to fall ill with particular diseases [1,2] and help to design "personalized medicine" [3]. Moreover, statistical studies and comparison of genomes [4]…

Emerging high-throughput technologies have led to a deluge of putative non-coding RNA (ncRNA) sequences identified in a wide variety of organisms. Systematic characterization of these transcripts will be a tremendous challenge. Homology…

Biomolecules · Quantitative Biology 2016-01-27 Lars Barquist , Sarah W. Burge , Paul P. Gardner

Human Pose Estimation (HPE) is increasingly important for applications like virtual reality and motion analysis, yet current methods struggle with balancing accuracy, computational efficiency, and reliable uncertainty quantification (UQ).…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Shipeng Liu , Ziliang Xiong , Bastian Wandt , Per-Erik Forssén

Fingerprinting-based positioning, one of the promising indoor positioning solutions, has been broadly explored owing to the pervasiveness of sensor-rich mobile devices, the prosperity of opportunistically measurable location-relevant…

Machine Learning · Statistics 2019-12-20 Caifa Zhou

While deep neural networks (DNNs) are used for prediction, inference on DNN-estimated subject-specific means for categorical or exponential family outcomes remains underexplored. We address this by proposing a DNN estimator under…

Machine Learning · Statistics 2026-03-18 Xuran Meng , Yi Li