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The primary motivation and application in this article come from brain imaging studies on cognitive impairment in elderly subjects with brain disorders. We propose a regularized Haar wavelet-based approach for the analysis of…

Applications · Statistics 2014-08-11 Xuejing Wang , Bin Nan , Ji Zhu , Robert Koeppe

Predicting behavioral variables from neuroimaging modalities such as magnetic resonance imaging (MRI) has the potential to allow the development of neuroimaging biomarkers of mental and neurological disorders. A crucial processing step to…

Neurons and Cognition · Quantitative Biology 2025-07-29 Mikkel Schöttner Sieler , Thomas A. W. Bolton , Jagruti Patel , Patric Hagmann

Graphical models have been used extensively for modeling brain connectivity networks. However, unmeasured confounders and correlations among measurements are often overlooked during model fitting, which may lead to spurious scientific…

Methodology · Statistics 2020-12-10 Yanxin Jin , Yang Ning , Kean Ming Tan

We show dense voxel embeddings learned via deep metric learning can be employed to produce a highly accurate segmentation of neurons from 3D electron microscopy images. A "metric graph" on a set of edges between voxels is constructed from…

Computer Vision and Pattern Recognition · Computer Science 2021-08-09 Kisuk Lee , Ran Lu , Kyle Luther , H. Sebastian Seung

The average human brain volume of the males is larger than that of the females. Several MRI voxel-based morphometry studies show that the gray matter/white matter ratio is larger in females. Here we have analyzed the recent public release…

Neurons and Cognition · Quantitative Biology 2016-04-21 Balázs Szalkai , Vince Grolmusz

First-episode schizophrenia (FES) results in abnormality of brain connectivity at different levels. Despite some successful findings on functional and structural connectivity of FES, relatively few studies have been focused on morphological…

Neurons and Cognition · Quantitative Biology 2022-12-27 Mowen Yin , Weikai Huang , Zhichao Liang , Quanying Liu , Xiaoying Tang

Focal Cortical Dysplasia (FCD) is a primary cause of drug-resistant epilepsy and is difficult to detect in brain {magnetic resonance imaging} (MRI) due to the subtle and small-scale nature of its lesions. Accurate segmentation of FCD…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Mehdi Rabiee , Sergio Greco , Reza Shahbazian , Irina Trubitsyna

We propose a geometric framework for longitudinal multi-parametric MRI analysis based on patient-specific energy modelling in sequence space. Rather than operating on images with spatial networks, each voxel is represented by its…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Kartikay Tehlan , Lukas Förner , Sina Wendrich , Nico Schmutzenhofer , Michael Frühwald , Matthias Wagner , Nassir Navab , Thomas Wendler

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. In this study, complexity specific image categorization across different visual datasets…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Vamshi K. Kancharala , Debanjali Bhattacharya , Neelam Sinha

We present a novel cortically-inspired image completion algorithm. It uses a five dimensional sub-Riemannian cortical geometry modelling the orientation, spatial frequency and phase selective behavior of the cells in the visual cortex. The…

Computer Vision and Pattern Recognition · Computer Science 2022-03-07 Emre Baspinar

Mapping the brain imaging data to networks, where each node represents a specific area of the brain, has enabled an objective graph-theoretic analysis of human connectome. However, the latent structure on higher-order connections remains…

Neurons and Cognition · Quantitative Biology 2019-04-09 Bosiljka Tadic , Miroslav Andjelkovic , Roderick Melnik

Functional magnetic resonance imaging (fMRI) is a crucial technology for gaining insights into cognitive processes in humans. Data amassed from fMRI measurements result in volumetric data sets that vary over time. However, analysing such…

Neurons and Cognition · Quantitative Biology 2020-10-23 Bastian Rieck , Tristan Yates , Christian Bock , Karsten Borgwardt , Guy Wolf , Nicholas Turk-Browne , Smita Krishnaswamy

Current AI frameworks for brain decoding and encoding, typically train and test models within the same datasets. This limits their utility for brain computer interfaces (BCI) or neurofeedback, for which it would be useful to pool…

The goal of emotional brain state classification on functional MRI (fMRI) data is to recognize brain activity patterns related to specific emotion tasks performed by subjects during an experiment. Distinguishing emotional brain states from…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Maxime Tchibozo , Donggeun Kim , Zijing Wang , Xiaofu He

Reconstructing seeing images from fMRI recordings is an absorbing research area in neuroscience and provides a potential brain-reading technology. The challenge lies in that visual encoding in brain is highly complex and not fully revealed.…

Neural and Evolutionary Computing · Computer Science 2021-01-29 Tao Fang , Yu Qi , Gang Pan

Synthetic neuroimaging data can mitigate critical limitations of real-world datasets, including the scarcity of rare phenotypes, domain shifts across scanners, and insufficient longitudinal coverage. However, existing generative models…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Fabian Bongratz , Yitong Li , Sama Elbaroudy , Christian Wachinger

We present a multi-scale spiking network model of all vision-related areas of macaque cortex that represents each area by a full-scale microcircuit with area-specific architecture. The layer- and population-resolved network connectivity…

Neurons and Cognition · Quantitative Biology 2018-10-23 Maximilian Schmidt , Rembrandt Bakker , Kelly Shen , Gleb Bezgin , Claus-Christian Hilgetag , Markus Diesmann , Sacha J. van Albada

Computing volumetric correspondences between 3D shapes is a prominent tool for medical and industrial applications. In this work, we pave the way for spectral volume mapping, extending for the first time the surface-based functional maps…

Graphics · Computer Science 2026-03-19 Filippo Maggioli , Simone Melzi , Marco Livesu

Understanding the intricate architecture of brain networks and its connection to brain function is essential for deciphering the underlying principles of cognition and disease. While traditional graph-theoretical measures have been widely…

Chaotic Dynamics · Physics 2025-11-13 Anca Radulescu , Eva Kaslik , Alexandru Fikl , Johan Nakuci , Sarah Muldoon , Michael Anderson

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington