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The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

Neurons and Cognition · Quantitative Biology 2019-02-21 Sevil Maghsadhagh , Anders Eklund , Hamid Behjat

The human brain cortical layer has a convoluted morphology that is unique to each individual. Characterization of the cortical morphology is necessary in longitudinal studies of structural brain change, as well as in discriminating…

Computer Vision and Pattern Recognition · Computer Science 2018-10-25 Sevil Maghsadhagh , Mousa Shamsi , Anders Eklund , Hamid Behjat

Surface analysis of the cortex is ubiquitous in human neuroimaging with MRI, e.g., for cortical registration, parcellation, or thickness estimation. The convoluted cortical geometry requires isotropic scans (e.g., 1mm MPRAGEs) and good…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Karthik Gopinath , Douglas N. Greve , Sudeshna Das , Steve Arnold , Colin Magdamo , Juan Eugenio Iglesias

Current connectivity diagrams of human brain image data are either overly complex or overly simplistic. In this work we introduce simple yet accurate interactive visual representations of multiple brain image structures and the connectivity…

Graphics · Computer Science 2016-09-02 Saad Nadeem , Arie Kaufman

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

Neurons and Cognition · Quantitative Biology 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

The frequency-specific coupling mechanism of the functional human brain networks underpins its complex cognitive and behavioral functions. Nevertheless, it is not well unveiled what are the frequency-specific subdivisions and network…

Neurons and Cognition · Quantitative Biology 2021-03-30 Zhiguo Luo , Ling-Li Zeng , Hui Shen , Dewen Hu

Functional Magnetic Resonance Imaging (fMRI) is a powerful non-invasive tool for localizing and analyzing brain activity. This study focuses on one very important aspect of the functional properties of human brain, specifically the…

Artificial Intelligence · Computer Science 2014-10-28 Harris V. Georgiou

We propose a framework for jointly modeling the geometry and functionality in high dimensional functional surfaces. The proposed mixed effects model characterizes effects of subject-specific covariates and exogenous stimuli on functional…

Applications · Statistics 2023-02-10 Jingjing Zou , Chi-Hua Chen , John A. D. Aston

Conventional visualization media such as MRI prints and computer screens are inherently two dimensional, making them incapable of displaying true 3D volume data sets. By applying only transparency or intensity projection, and ignoring…

Graphics · Computer Science 2007-05-23 Gibby Koldenhof

Identifying cerebral cortex layers is crucial for comparative studies of the cytoarchitecture aiming at providing insights into the relations between brain structure and function across species. The absence of extensive annotated datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-11-28 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Giulia Vadori , Livio Finos , Enrico Grisan

Deep learning shows high potential for many medical image analysis tasks. Neural networks can work with full-size data without extensive preprocessing and feature generation and, thus, information loss. Recent work has shown that the…

Functional MRI (fMRI) has become the most common method for investigating the human brain. However, fMRI data present some complications for statistical analysis and modeling. One recently developed approach to these data focuses on…

Applications · Statistics 2015-03-19 Vincent Q. Vu , Pradeep Ravikumar , Thomas Naselaris , Kendrick N. Kay , Jack L. Gallant , Bin Yu

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

The thickness of the cortical band is linked to various neurological and psychiatric conditions, and is often estimated through surface-based methods such as Freesurfer in MRI studies. The DiReCT method, which calculates cortical thickness…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Richard McKinley , Christian Rummel

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

We present a novel way to model diffusion magnetic resonance imaging (dMRI) datasets, that benefits from the structural coherence of the human brain while only using data from a single subject. Current methods model the dMRI signal in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Tom Hendriks , Anna Vilanova , Maxime Chamberland

The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines…

Computer Vision and Pattern Recognition · Computer Science 2022-03-21 Fabian Bongratz , Anne-Marie Rickmann , Sebastian Pölsterl , Christian Wachinger

Cortical folding exhibits substantial inter-individual variability while preserving stable anatomical landmarks that enable fine-scale characterization of cortical organization. Among these, the three-hinge gyrus (3HG) serves as a key…

Neurons and Cognition · Quantitative Biology 2026-02-03 Minheng Chen , Tong Chen , Yan Zhuang , Chao Cao , Jing Zhang , Tianming Liu , Lu Zhang , Dajiang Zhu

In neuroscience, understanding inter-individual differences has recently emerged as a major challenge, for which functional magnetic resonance imaging (fMRI) has proven invaluable. For this, neuroscientists rely on basic methods such as…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Akrem Sellami , François-Xavier Dupé , Bastien Cagna , Hachem Kadri , Stéphane Ayache , Thierry Artières , Sylvain Takerkart
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