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A simple, but ``classical``, stochastic model for epidemic spread in a finite, but large, population is studied. The progress of the epidemic can be divided into three different phases that requires different tools to analyse. Initially the…

Populations and Evolution · Quantitative Biology 2018-05-29 Åke Svensson

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

Infectious diseases are practically represented by models with multiple states and complex transition rules corresponding to, for example, birth, death, infection, recovery, disease progression, and quarantine. In addition, networks…

Disordered Systems and Neural Networks · Physics 2007-05-23 Naoki Masuda , Norio Konno

We show how one can trace in a systematic way the coarse-grained solutions of individual-based stochastic epidemic models evolving on heterogeneous complex networks with respect to their topological characteristics. In particular, we have…

Social and Information Networks · Computer Science 2023-03-24 Andreas I. Reppas , Konstantinos Spiliotis , Constantinos Siettos

This paper investigates asymptotic behavior of a stochastic SIR epidemic model, which is a system with degenerate diffusion. It gives sufficient conditions that are very close to the necessary conditions for the permanence. In addition,…

Probability · Mathematics 2015-12-24 N. T. Dieu , D. H. Nguyen , N. H. Du , G. Yin

In this work, we provide an asymptotic analysis of the solutions to an elliptic integro-differential equation. This equation describes the evolutionary equilibria of a phenotypically structured population, subject to selection, mutation,…

Analysis of PDEs · Mathematics 2022-01-19 Alexis Léculier , Sepideh Mirrahimi

We propose a compartmental model for epidemiology wherein the population is split into groups with either comply or refuse to comply with protocols designed to slow the spread of a disease. Parallel to the disease spread, we assume that…

Dynamical Systems · Mathematics 2025-11-27 Christian Parkinson , Weinan Wang

The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…

Populations and Evolution · Quantitative Biology 2024-12-09 Daniel A. M. Villela

We investigate existence of stationary solutions to an aggregation/diffusion system of PDEs, modelling a two species predator-prey interaction. In the model this interaction is described by non-local potentials that are mutually…

Analysis of PDEs · Mathematics 2019-04-11 S. Fagioli , Y. Jaafra

In this paper, under an abstract setting we establish the spreading properties and the existence, non-existence and global attractivity of spatially heterogeneous steady states for a large class of monotone evolution systems without the…

Dynamical Systems · Mathematics 2025-10-22 Taishan Yi , Xiao-Qiang Zhao

We investigate the long-time dynamics of a SIR epidemic model with infinitely many pathogen variants infecting a homogeneous host population. We show that the basic reproduction number $\mathcal{R}_0$ of the pathogen can be defined in that…

Populations and Evolution · Quantitative Biology 2023-05-11 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

We consider a spatial stochastic model for a pathogen population growing inside a host that attempts to eliminate the pathogens through its immune system. The pathogen population is divided into different types. A pathogen can either…

Probability · Mathematics 2026-02-03 Fábio Lopes , Alejandro Roldán-Correa

The propagation of infectious diseases and its impact on individuals play a major role in disease dynamics, and it is important to incorporate population heterogeneity into efforts to study diseases. As a simplistic but illustrative…

Populations and Evolution · Quantitative Biology 2019-07-24 Juan G. Calvo , Alberto Hernández , Mason A. Porter , Fabio Sanchez

We use a multitype continuous time Markov branching process model to describe the dynamics of the spread of parasites of two types that can mutate into each other in a common host population. Instead of using a single virulence…

Probability · Mathematics 2011-09-02 Konstantin Borovkov , Robert Day , Timothy Rice

We study the probabilistic evolution of a birth and death continuous time measure-valued process with mutations and ecological interactions. The individuals are characterized by (phenotypic) traits that take values in a compact metric…

Probability · Mathematics 2009-04-23 Pierre Collet , Servet Martinez , Sylvie Méléard , Jaime San Martin

In microbial communities, each species often has multiple, distinct phenotypes, but studies of ecological stability have largely ignored this subpopulation structure. Here, we show that such implicit averaging over phenotypes leads to…

Populations and Evolution · Quantitative Biology 2020-05-20 Pierre A. Haas , Nuno M. Oliveira , Raymond E. Goldstein

The Master equation describes the time evolution of the probabilities of a system with a discrete state space. This time evolution approaches for long times a stationary state that will in general depend on the initial probability…

Mathematical Physics · Physics 2022-03-09 Bernd Fernengel , Barbara Drossel

We study a mathematical model describing the growth process of a population structured by age and a phenotypical trait, subject to aging, competition between individuals and rare mutations. Our goals are to describe the asymptotic behaviour…

Analysis of PDEs · Mathematics 2020-04-17 Samuel Nordmann , Benoît Perthame , Cécile Taing

A novel model of biological organisms is advanced, treating an organism as a self-consistent system subject to a pathogen flux. The principal novelty of the model is that it describes not some parts, but a biological organism as a whole.…

Biological Physics · Physics 2015-05-13 V. I. Yukalov , D. Sornette , E. P. Yukalova , J. -Y. Henry , J. P. Cobb

The dynamics of epidemic spreading is often reduced to the single control parameter $R_0$, whose value, above or below unity, determines the state of the contagion. If, however, the pathogen evolves as it spreads, $R_0$ may change over…

Populations and Evolution · Quantitative Biology 2022-11-07 Xiyun Zhang , Zhongyuan Ruan , Muhua Zheng , Jie Zhou , Stefano Boccaletti , Baruch Barzel