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We consider the problem of learning causal DAGs in the setting where both observational and interventional data is available. This setting is common in biology, where gene regulatory networks can be intervened on using chemical reagents or…

Methodology · Statistics 2019-02-08 Karren D. Yang , Abigail Katcoff , Caroline Uhler

It is known that from purely observational data, a causal DAG is identifiable only up to its Markov equivalence class, and for many ground truth DAGs, the direction of a large portion of the edges will be remained unidentified. The golden…

Machine Learning · Computer Science 2019-10-15 AmirEmad Ghassami , Saber Salehkaleybar , Negar Kiyavash

We consider the problem of learning causal Directed Acyclic Graphs (DAGs) using combinations of observational and interventional experimental data. Current methods tailored to this setting assume that interventions either destroy…

Methodology · Statistics 2023-12-04 Alessandro Mascaro , Federico Castelletti

The investigation of directed acyclic graphs (DAGs) encoding the same Markov property, that is the same conditional independence relations of multivariate observational distributions, has a long tradition; many algorithms exist for model…

Methodology · Statistics 2012-09-27 Alain Hauser , Peter Bühlmann

The increasing availability of interventional data offers new opportunities for causal discovery, with gene perturbation studies providing a prominent example. Such data are typically count-valued and subject to substantial measurement…

Methodology · Statistics 2026-03-30 Yijiao Zhang , Hongzhe Li

The problem of learning a directed acyclic graph (DAG) up to Markov equivalence is equivalent to the problem of finding a permutation of the variables that induces the sparsest graph. Without additional assumptions, this task is known to be…

Methodology · Statistics 2020-11-10 Chandler Squires , Joshua Amaniampong , Caroline Uhler

Causal discovery is a fundamental problem with applications spanning various areas in science and engineering. It is well understood that solely using observational data, one can only orient the causal graph up to its Markov equivalence…

Machine Learning · Computer Science 2024-10-29 Zihan Zhou , Muhammad Qasim Elahi , Murat Kocaoglu

This paper studies the causal representation learning problem when the latent causal variables are observed indirectly through an unknown linear transformation. The objectives are: (i) recovering the unknown linear transformation (up to…

Machine Learning · Statistics 2023-05-02 Burak Varici , Emre Acarturk , Karthikeyan Shanmugam , Abhishek Kumar , Ali Tajer

Describing the causal relations governing a system is a fundamental task in many scientific fields, ideally addressed by experimental studies. However, obtaining data under intervention scenarios may not always be feasible, while…

Methodology · Statistics 2022-05-06 Jack Kuipers , Giusi Moffa

We establish conditions under which latent causal graphs are nonparametrically identifiable and can be reconstructed from unknown interventions in the latent space. Our primary focus is the identification of the latent structure in…

Machine Learning · Statistics 2023-11-06 Yibo Jiang , Bryon Aragam

Learning causal relationships between variables is a fundamental task in causal inference and directed acyclic graphs (DAGs) are a popular choice to represent the causal relationships. As one can recover a causal graph only up to its Markov…

Machine Learning · Computer Science 2024-02-14 Davin Choo , Kirankumar Shiragur

This paper considers the problem of estimating the unknown intervention targets in a causal directed acyclic graph from observational and interventional data. The focus is on soft interventions in linear structural equation models (SEMs).…

Methodology · Statistics 2021-11-16 Burak Varici , Karthikeyan Shanmugam , Prasanna Sattigeri , Ali Tajer

Identification theory for causal effects in causal models associated with hidden variable directed acyclic graphs (DAGs) is well studied. However, the corresponding algorithms are underused due to the complexity of estimating the…

Machine Learning · Statistics 2022-10-17 Rohit Bhattacharya , Razieh Nabi , Ilya Shpitser

Bayesian causal discovery aims to infer the posterior distribution over causal models from observed data, quantifying epistemic uncertainty and benefiting downstream tasks. However, computational challenges arise due to joint inference over…

Machine Learning · Computer Science 2023-12-11 Yashas Annadani , Nick Pawlowski , Joel Jennings , Stefan Bauer , Cheng Zhang , Wenbo Gong

From observational data alone, a causal DAG is only identifiable up to Markov equivalence. Interventional data generally improves identifiability; however, the gain of an intervention strongly depends on the intervention target, that is,…

Methodology · Statistics 2014-06-03 Alain Hauser , Peter Bühlmann

New biological assays like Perturb-seq link highly parallel CRISPR interventions to a high-dimensional transcriptomic readout, providing insight into gene regulatory networks. Causal gene regulatory networks can be represented by directed…

Machine Learning · Statistics 2024-02-22 Albert Xue , Jingyou Rao , Sriram Sankararaman , Harold Pimentel

Causal representation learning aims to recover the latent causal variables and their causal relations, typically represented by directed acyclic graphs (DAGs), from low-level observations such as image pixels. A prevailing line of research…

Machine Learning · Computer Science 2026-04-28 Ignavier Ng , Shaoan Xie , Xinshuai Dong , Peter Spirtes , Kun Zhang

Learning the causal structure that underlies data is a crucial step towards robust real-world decision making. The majority of existing work in causal inference focuses on determining a single directed acyclic graph (DAG) or a Markov…

Machine Learning · Computer Science 2021-06-15 Yashas Annadani , Jonas Rothfuss , Alexandre Lacoste , Nino Scherrer , Anirudh Goyal , Yoshua Bengio , Stefan Bauer

In this review, we discuss approaches for learning causal structure from data, also called causal discovery. In particular, we focus on approaches for learning directed acyclic graphs (DAGs) and various generalizations which allow for some…

Methodology · Statistics 2022-12-20 Chandler Squires , Caroline Uhler

In the context of inferring a Bayesian network structure (directed acyclic graph, DAG for short), we devise a non-reversible continuous time Markov chain, the ``Causal Zig-Zag sampler'', that targets a probability distribution over classes…

Machine Learning · Statistics 2024-09-12 Moritz Schauer , Marcel Wienöbst
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