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Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal…

Methodology · Statistics 2024-08-14 Carlo Berzuini , Davide Luciani , Hiren C. Patel

The causal relationships among a set of random variables are commonly represented by a Directed Acyclic Graph (DAG), where there is a directed edge from variable $X$ to variable $Y$ if $X$ is a direct cause of $Y$. From the purely…

Machine Learning · Statistics 2020-06-18 Ali AhmadiTeshnizi , Saber Salehkaleybar , Negar Kiyavash

Learning causal relationships between variables from data is a fundamental research area with many applications across disciplines. Most existing causal discovery algorithms rely on the assumptions that (i) the underlying system is acyclic,…

Machine Learning · Computer Science 2026-05-19 Alpar Turkoglu , Muralikrishnna G. Sethuraman , Faramarz Fekri

Identifying controlled direct effects (CDEs) is crucial across numerous scientific domains. While existing methods can identify these effects from causal directed acyclic graphs (DAGs), the true DAG is often unknown in practice. Essential…

Artificial Intelligence · Computer Science 2026-04-09 Timothée Loranchet , Charles K. Assaad

We study the problem of actively learning a non-parametric choice model based on consumers' decisions. We present a negative result showing that such choice models may not be identifiable. To overcome the identifiability problem, we…

Machine Learning · Computer Science 2024-04-26 Fransisca Susan , Negin Golrezaei , Ehsan Emamjomeh-Zadeh , David Kempe

In recent years, causal modelling has been used widely to improve generalization and to provide interpretability in machine learning models. To determine cause-effect relationships in the absence of a randomized trial, we can model causal…

Machine Learning · Computer Science 2021-06-03 Rohan Giriraj , Sinnu Susan Thomas

Capturing the underlying structural causal relations represented by Directed Acyclic Graphs (DAGs) has been a fundamental task in various AI disciplines. Causal DAG learning via the continuous optimization framework has recently achieved…

Machine Learning · Computer Science 2024-06-11 Naiyu Yin , Tian Gao , Yue Yu , Qiang Ji

We provide explicit, finite-sample guarantees for learning causal representations from data with a sublinear number of environments. Causal representation learning seeks to provide a rigourous foundation for the general representation…

Machine Learning · Statistics 2026-03-30 Inbeom Lee , Tongtong Jin , Bryon Aragam

In the domain generalization literature, a common objective is to learn representations independent of the domain after conditioning on the class label. We show that this objective is not sufficient: there exist counter-examples where a…

Machine Learning · Computer Science 2021-06-30 Divyat Mahajan , Shruti Tople , Amit Sharma

The ability to answer causal questions is crucial in many domains, as causal inference allows one to understand the impact of interventions. In many applications, only a single intervention is possible at a given time. However, in some…

Machine Learning · Statistics 2022-10-12 Olivier Jeunen , Ciarán M. Gilligan-Lee , Rishabh Mehrotra , Mounia Lalmas

Estimating the structure of directed acyclic graphs (DAGs, also known as Bayesian networks) is a challenging problem since the search space of DAGs is combinatorial and scales superexponentially with the number of nodes. Existing approaches…

Machine Learning · Statistics 2018-11-06 Xun Zheng , Bryon Aragam , Pradeep Ravikumar , Eric P. Xing

Learning the structure of directed acyclic graphs (DAGs) from observational data is a central problem in causal discovery, statistical signal processing, and machine learning. Under a linear Gaussian structural equation model (SEM) with…

Machine Learning · Computer Science 2026-05-27 Hamed Ajorlou , Samuel Rey , Gonzalo Mateos , Geert Leus , Antonio G. Marques

The search space of Bayesian Network structures is usually defined as Acyclic Directed Graphs (DAGs) and the search is done by local transformations of DAGs. But the space of Bayesian Networks is ordered by DAG Markov model inclusion and it…

Machine Learning · Computer Science 2013-01-14 Tomas Kocka , Robert Castelo

Nonlinear causal discovery from observational data imposes strict identifiability assumptions on the formulation of structural equations utilized in the data generating process. The evaluation of structure learning methods under assumption…

Machine Learning · Statistics 2024-12-17 Georg Velev , Stefan Lessmann

Telling apart the cause and effect between two random variables with purely observational data is a challenging problem that finds applications in various scientific disciplines. A key principle utilized in this task is the algorithmic…

Machine Learning · Computer Science 2025-08-15 Quang-Duy Tran , Bao Duong , Phuoc Nguyen , Thin Nguyen

We study two problems related to recovering causal graphs from interventional data: (i) $\textit{verification}$, where the task is to check if a purported causal graph is correct, and (ii) $\textit{search}$, where the task is to recover the…

Machine Learning · Computer Science 2022-10-11 Davin Choo , Kirankumar Shiragur , Arnab Bhattacharyya

Selective conformal prediction can yield substantially tighter uncertainty sets when we can identify calibration examples that are exchangeable with the test example. In interventional settings, such as perturbation experiments in genomics,…

Machine Learning · Computer Science 2026-03-03 Amir Asiaee , Kavey Aryan , James P. Long

Causal structures for observational survival data provide crucial information regarding the relationships between covariates and time-to-event. We derive motivation from the information theoretic source coding argument, and show that…

Machine Learning · Computer Science 2021-11-03 Ansh Kumar Sharma , Rahul Kukreja , Ranjitha Prasad , Shilpa Rao

Causal inference quantifies cause-effect relationships by estimating counterfactual parameters from data. This entails using \emph{identification theory} to establish a link between counterfactual parameters of interest and distributions…

Machine Learning · Statistics 2020-04-17 Jaron J. R. Lee , Ilya Shpitser

The prediction modeling of drug-target interactions is crucial to drug discovery and design, which has seen rapid advancements owing to deep learning technologies. Recently developed methods, such as those based on graph neural networks…

Quantitative Methods · Quantitative Biology 2025-11-19 Xinnan Zhang , Jialin Wu , Junyi Xie , Tianlong Chen , Kaixiong Zhou
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