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We introduce a novel statistical significance-based approach for clustering hierarchical data using semi-parametric linear mixed-effects models designed for responses with laws in the exponential family (e.g., Poisson and Bernoulli). Within…
Data clustering, the task of grouping observations according to their similarity, is a key component of unsupervised learning -- with real world applications in diverse fields such as biology, medicine, and social science. Often in these…
A novel approach rooted on the notion of consensus clustering, a strategy developed for community detection in complex networks, is proposed to cope with the heterogeneity that characterizes connectivity matrices in health and disease. The…
Being able to design genetic regulatory networks (GRNs) to achieve a desired cellular function is one of the main goals of synthetic biology. However, determining minimal GRNs that produce desired time-series behaviors is non-trivial. In…
Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…
Given the potential difficulties in obtaining large quantities of labelled data, many works have explored the use of deep semi-supervised learning, which uses both labelled and unlabelled data to train a neural network architecture. The…
A daunting challenge faced by modern biological sciences is finding an efficient and computationally feasible approach to deal with the curse of high dimensionality. The problem becomes even more severe when the research focus is on…
Semi-supervised clustering techniques have emerged as valuable tools for leveraging prior information in the form of constraints to improve the quality of clustering outcomes. Despite the proliferation of such methods, the ability to…
Partitioning a graph into groups of vertices such that those within each group are more densely connected than vertices assigned to different groups, known as graph clustering, is often used to gain insight into the organisation of large…
Clustering is an unsupervised machine learning methodology where unlabeled elements/objects are grouped together aiming to the construction of well-established clusters that their elements are classified according to their similarity. The…
Graph Neural Networks (GNNs) have achieved promising performance in semi-supervised node classification in recent years. However, the problem of insufficient supervision, together with representation collapse, largely limits the performance…
Recent developed deep unsupervised methods allow us to jointly learn representation and cluster unlabelled data. These deep clustering methods mainly focus on the correlation among samples, e.g., selecting high precision pairs to gradually…
Differently from theoretical scale-free networks, most of real networks present multi-scale behavior with nodes structured in different types of functional groups and communities. While the majority of approaches for classification of nodes…
Hierarchical clustering is one of the most powerful solutions to the problem of clustering, on the grounds that it performs a multi scale organization of the data. In recent years, research on hierarchical clustering methods has attracted…
Graph-based semi-supervised node classification has been shown to become a state-of-the-art approach in many applications with high research value and significance. Most existing methods are only based on the original intrinsic or…
The graph convolution network (GCN) is a widely-used facility to realize graph-based semi-supervised learning, which usually integrates node features and graph topologic information to build learning models. However, as for multi-label…
Unsupervised person re-identification (Re-ID) attracts increasing attention due to its potential to resolve the scalability problem of supervised Re-ID models. Most existing unsupervised methods adopt an iterative clustering mechanism,…
In recent years, there are many research cases for the diagnosis of Parkinson's disease (PD) with the brain magnetic resonance imaging (MRI) by utilizing the traditional unsupervised machine learning methods and the supervised deep learning…
Hierarchical classification is a crucial task in many applications, where objects are organized into multiple levels of categories. However, conventional classification approaches often neglect inherent inter-class relationships at…
Graph Convolutional Networks (GCNs) show promising results for semi-supervised learning tasks on graphs, thus become favorable comparing with other approaches. Despite the remarkable success of GCNs, it is difficult to train GCNs with…