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Modern graph or network datasets often contain rich structure that goes beyond simple pairwise connections between nodes. This calls for complex representations that can capture, for instance, edges of different types as well as so-called…

Social and Information Networks · Computer Science 2020-02-19 Ilya Amburg , Nate Veldt , Austin R. Benson

Constrained clustering has been well-studied in the unsupervised learning society. However, how to encode constraints into community structure detection, within complex networks, remains a challenging problem. In this paper, we propose a…

Social and Information Networks · Computer Science 2013-03-25 Zhong-Yuan Zhang

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

A novel method to obtain hierarchical and overlapping clusters from network data -i.e., a set of nodes endowed with pairwise dissimilarities- is presented. The introduced method is hierarchical in the sense that it outputs a nested…

Social and Information Networks · Computer Science 2017-12-13 Fernando Gama , Santiago Segarra , Alejandro Ribeiro

Determining phenotypes of diseases can have considerable benefits for in-hospital patient care and to drug development. The structure of high dimensional data sets such as electronic health records are often represented through an embedding…

Graphs have become increasingly popular in modeling structures and interactions in a wide variety of problems during the last decade. Graph-based clustering and semi-supervised classification techniques have shown impressive performance.…

Machine Learning · Computer Science 2020-09-01 Zhao Kang , Chong Peng , Qiang Cheng , Xinwang Liu , Xi Peng , Zenglin Xu , Ling Tian

Medical data often exhibit characteristics that make cluster analysis particularly challenging, such as missing values, outliers, and cluster features like skewness. Typically, such data would need to be preprocessed -- by cleaning outliers…

Methodology · Statistics 2025-12-16 Jason Pillay , Cristina Tortora , Antonio Punzo , Andriette Bekker

Self-supervised heterogeneous graph learning (SHGL) has shown promising potential in diverse scenarios. However, while existing SHGL methods share a similar essential with clustering approaches, they encounter two significant limitations:…

Artificial Intelligence · Computer Science 2024-12-03 Yujie Mo , Zhihe Lu , Runpeng Yu , Xiaofeng Zhu , Xinchao Wang

Determining the functional structure of biological networks is a central goal of systems biology. One approach is to analyze gene expression data to infer a network of gene interactions on the basis of their correlated responses to…

Quantitative Methods · Quantitative Biology 2015-06-03 Santiago Treviño , Yudong Sun , Tim F. Cooper , Kevin E. Bassler

In this paper, we introduce a neural network framework for semi-supervised clustering (SSC) with pairwise (must-link or cannot-link) constraints. In contrast to existing approaches, we decompose SSC into two simpler classification…

Machine Learning · Computer Science 2020-01-22 Marek Śmieja , Łukasz Struski , Mário A. T. Figueiredo

This paper studies semi-supervised graph classification, a crucial task with a wide range of applications in social network analysis and bioinformatics. Recent works typically adopt graph neural networks to learn graph-level representations…

Machine Learning · Computer Science 2023-04-25 Wei Ju , Xiao Luo , Meng Qu , Yifan Wang , Chong Chen , Minghua Deng , Xian-Sheng Hua , Ming Zhang

Clustering analysis is fundamental in single-cell RNA sequencing (scRNA-seq) data analysis for elucidating cellular heterogeneity and diversity. Recent graph-based scRNA-seq clustering methods, particularly graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-07-15 Ping Xu , Pengfei Wang , Zhiyuan Ning , Meng Xiao , Min Wu , Yuanchun Zhou

Traditional clustering methods often perform clustering with low-level indiscriminative representations and ignore relationships between patterns, resulting in slight achievements in the era of deep learning. To handle this problem, we…

Machine Learning · Computer Science 2019-05-07 Jianlong Chang , Yiwen Guo , Lingfeng Wang , Gaofeng Meng , Shiming Xiang , Chunhong Pan

Detecting and discovering new gene interactions based on known gene expressions and gene interaction data presents a significant challenge. Various statistical and deep learning methods have attempted to tackle this challenge by leveraging…

Machine Learning · Computer Science 2023-10-09 Ahmed Fakhry , Raneem Khafagy , Adriaan-Alexander Ludl

Incomplete multi-view clustering has become one of the important research problems due to the extensive missing multi-view data in the real world. Although the existing methods have made great progress, there are still some problems: 1)…

Machine Learning · Computer Science 2025-02-27 Guoqing Chao , Kaixin Xu , Xijiong Xie , Yongyong Chen

In this study, we tested the interaction effect of multimodal datasets using a novel method called the kernel method for detecting higher order interactions among biologically relevant mulit-view data. Using a semiparametric method on a…

Machine Learning · Statistics 2017-07-17 Md. Ashad Alam , Hui-Yi Lin , Vince Calhoun , Yu-Ping Wang

There has been a surge in the number of large and flat data sets - data sets containing a large number of features and a relatively small number of observations - due to the growing ability to collect and store information in medical…

Machine Learning · Statistics 2017-07-05 Hongyang Zhang , Ruben H. Zamar

The paper tackles the problem of clustering multiple networks, directed or not, that do not share the same set of vertices, into groups of networks with similar topology. A statistical model-based approach based on a finite mixture of…

Statistics Theory · Mathematics 2023-11-07 Tabea Rebafka

Deep convolutional neural network (DCNN) based supervised learning is a widely practiced approach for large-scale image classification. However, retraining these large networks to accommodate new, previously unseen data demands high…

Computer Vision and Pattern Recognition · Computer Science 2020-03-26 Syed Shakib Sarwar , Aayush Ankit , Kaushik Roy

Face clustering is an essential tool for exploiting the unlabeled face data, and has a wide range of applications including face annotation and retrieval. Recent works show that supervised clustering can result in noticeable performance…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Lei Yang , Dapeng Chen , Xiaohang Zhan , Rui Zhao , Chen Change Loy , Dahua Lin