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Normative aging trends of the brain can serve as an important reference in the assessment of neurological structural disorders. Such models are typically developed from longitudinal brain image data -- follow-up data of the same subject…

Computer Vision and Pattern Recognition · Computer Science 2021-06-29 Alphin J Thottupattu , Jayanthi Sivaswamy , Venkateswaran P. Krishnan

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

The complex multi-stage architecture of cortical visual pathways provides the neural basis for efficient visual object recognition in humans. However, the stage-wise computations therein remain poorly understood. Here, we compared temporal…

Computer Vision and Pattern Recognition · Computer Science 2016-01-13 Radoslaw M. Cichy , Aditya Khosla , Dimitrios Pantazis , Antonio Torralba , Aude Oliva

The brain's biological age has been considered as a promising candidate for a neurologically significant biomarker. However, recent results based on longitudinal magnetic resonance imaging data have raised questions on its interpretation. A…

Neurons and Cognition · Quantitative Biology 2023-10-12 Lukas AW Gemein , Robin T Schirrmeister , Joschka Boedecker , Tonio Ball

Our demonstration shows a system that estimates internal body structures from 3D surface models using deep convolutional neural networks trained on CT (computed tomography) images of the human body. To take pictures of structures inside the…

Computer Vision and Pattern Recognition · Computer Science 2018-01-08 Takumi Moriya , Kazuyuki Saito , Hiroya Tanaka

Accurate and reproducible measurements of the aortic diameters are crucial for the diagnosis of cardiovascular diseases and for therapeutic decision making. Currently, these measurements are manually performed by healthcare professionals,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Axel Aguerreberry , Ezequiel de la Rosa , Alain Lalande , Elmer Fernandez

Many high-performance classification models utilize complex CNN-based architectures for Alzheimer's Disease classification. We aim to investigate two relevant questions regarding classification of Alzheimer's Disease using MRI: "Do Vision…

Image and Video Processing · Electrical Eng. & Systems 2022-10-05 Zilun Zhang , Farzad Khalvati

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Deep learning builds the foundation for many medical image analysis tasks where neuralnetworks are often designed to have a large receptive field to incorporate long spatialdependencies. Recent work has shown that large receptive fields are…

Image and Video Processing · Electrical Eng. & Systems 2019-07-27 Nick Pawlowski , Ben Glocker

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

Image and Video Processing · Electrical Eng. & Systems 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

3D reconstruction is a longstanding ill-posed problem, which has been explored for decades by the computer vision, computer graphics, and machine learning communities. Since 2015, image-based 3D reconstruction using convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-28 Xian-Feng Han , Hamid Laga , Mohammed Bennamoun

Computer-aided medical image analysis plays a significant role in assisting medical practitioners for expert clinical diagnosis and deciding the optimal treatment plan. At present, convolutional neural networks (CNN) are the preferred…

Image and Video Processing · Electrical Eng. & Systems 2022-04-29 S Niyas , S J Pawan , M Anand Kumar , Jeny Rajan

The study of signatures of aging in terms of genomic biomarkers can be uniquely helpful in understanding the mechanisms of aging and developing models to accurately predict the age. Prior studies have employed gene expression and DNA…

Genomics · Quantitative Biology 2021-11-08 Salman Mohamadi , Gianfranco. Doretto , Nasser M. Nasrabadi , Donald A. Adjeroh

Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert

Magnetic Resonance Imaging (MRI) is one of the most flexible and powerful medical imaging modalities. This flexibility does however come at a cost; MRI images acquired at different sites and with different parameters exhibit significant…

Biomechanical modeling of tissue deformation can be used to simulate different scenarios of longitudinal brain evolution. In this work,we present a deep learning framework for hyper-elastic strain modelling of brain atrophy, during healthy…

Neurons and Cognition · Quantitative Biology 2021-08-19 Mariana Da Silva , Carole H. Sudre , Kara Garcia , Cher Bass , M. Jorge Cardoso , Emma C. Robinson

Deep learning (DL) methods are increasingly outperforming classical approaches in brain imaging, yet their generalizability across diverse imaging cohorts remains inadequately assessed. As age and sex are key neurobiological markers in…

In this work we propose a novel deep-learning approach for age estimation based on face images. We first introduce a dual image augmentation-aggregation approach based on attention. This allows the network to jointly utilize multiple face…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Shakediel Hiba , Yosi Keller

Transfer learning has remarkably improved computer vision. These advances also promise improvements in neuroimaging, where training set sizes are often small. However, various difficulties arise in directly applying models pretrained on…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Umang Gupta , Tamoghna Chattopadhyay , Nikhil Dhinagar , Paul M. Thompson , Greg Ver Steeg , The Alzheimer's Disease Neuroimaging Initiative

Changes over time in brain anatomy can provide important insight for treatment design or scientific analyses. We present a method that predicts how a brain MRI for an individual will change over time. We model changes using a diffeomorphic…

Computer Vision and Pattern Recognition · Computer Science 2020-06-02 Marianne Rakic , John Guttag , Adrian V. Dalca