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Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with…
During times of increasing antibiotic resistance and the spread of infectious diseases like COVID-19, it is important to classify genes related to antibiotic resistance. As natural language processing has advanced with transformer-based…
This paper proposes a novel weakly-supervised semantic segmentation method using image-level label only. The class-specific activation maps from the well-trained classifiers are used as cues to train a segmentation network. The well-known…
Hierarchical multi-label classification (HMC) is a challenging classification task extending standard multi-label classification problems by imposing a hierarchy constraint on the classes. In this paper, we propose C-HMCNN(h), a novel…
Binary classification (BC) is a practical task that is ubiquitous in real-world problems, such as distinguishing healthy and unhealthy objects in biomedical diagnostics and defective and non-defective products in manufacturing inspections.…
Behavioral malware detection aims to improve on the performance of static signature-based techniques used by anti-virus systems, which are less effective against modern polymorphic and metamorphic malware. Behavioral malware classification…
The rapid spread of the COVID-19 pandemic has resulted in an unprecedented amount of sequence data of the SARS-CoV-2 genome -- millions of sequences and counting. This amount of data, while being orders of magnitude beyond the capacity of…
We address the problem of model selection for Support Vector Machine (SVM) classification. For fixed functional form of the kernel, model selection amounts to tuning kernel parameters and the slack penalty coefficient $C$. We begin by…
Datasets containing both categorical and continuous variables are frequently encountered in many areas, and with the rapid development of modern measurement technologies, the dimensions of these variables can be very high. Despite the…
In this paper we propose a linear variable screening method for computer experiments when the number of input variables is larger than the number of runs. This method uses a linear model to model the nonlinear data, and screens the…
Semantic segmentation is still a challenging task for parsing diverse contexts in different scenes, thus the fixed classifier might not be able to well address varying feature distributions during testing. Different from the mainstream…
Large amounts of unlabelled data are commonplace for many applications in computational pathology, whereas labelled data is often expensive, both in time and cost, to acquire. We investigate the performance of unsupervised and supervised…
We consider learning a sequence classifier without labeled data by using sequential output statistics. The problem is highly valuable since obtaining labels in training data is often costly, while the sequential output statistics (e.g.,…
High dimensional classification has been highlighted for last two decades and much research has been conducted in order to circumvent challenges encountered in high dimensions. While existing methods have focused mainly on developing…
Within a supervised classification framework, labeled data are used to learn classifier parameters. Prior to that, it is generally required to perform dimensionality reduction via feature extraction. These preprocessing steps have motivated…
In epidemiological studies, the capture-recapture (CRC) method is a powerful tool that can be used to estimate the number of diseased cases or potentially disease prevalence based on data from overlapping surveillance systems. Estimators…
Diagnostic testing provides a unique setting for studying and developing tools in classification theory. In such contexts, the concept of prevalence, i.e. the number of individuals with a given condition, is fundamental, both as an inherent…
Computational complexity is a key limitation of genomic analyses. Thus, over the last 30 years, researchers have proposed numerous fast heuristic methods that provide computational relief. Comparing genomic sequences is one of the most…
Nuclear segmentation and classification is an essential step for computational pathology. TIA lab from Warwick University organized a nuclear segmentation and classification challenge (CoNIC) for H&E stained histopathology images in…
Semi-supervised learning plays an important role in large-scale machine learning. Properly using additional unlabeled data (largely available nowadays) often can improve the machine learning accuracy. However, if the machine learning model…