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The amount of sequencing data for SARS-CoV-2 is several orders of magnitude larger than any virus. This will continue to grow geometrically for SARS-CoV-2, and other viruses, as many countries heavily finance genomic surveillance efforts.…

Genomics · Quantitative Biology 2023-04-10 Sarwan Ali , Prakash Chourasia , Zahra Tayebi , Babatunde Bello , Murray Patterson

This paper investigates the variance reduction techniques Antithetic Variates (AV) and Latin Hypercube Sampling (LHS) when used for sequential sampling in stochastic programming and presents a comparative computational study. It shows…

Optimization and Control · Mathematics 2021-04-12 Jangho Park , Rebecca Stockbridge , Güzin Bayraksan

HIV-1C is the most prevalent subtype of HIV-1 and accounts for over half of HIV-1 infections worldwide. Host genetic influence of HIV infection has been previously studied in HIV-1B, but little attention has been paid to the more prevalent…

Methodology · Statistics 2017-06-13 Denis Agniel , Wen Xie , Myron Essex , Tianxi Cai

Background Achieving hepatitis C elimination is hampered by the costs of treatment and the need to treat hard-to-reach populations. Treatment access could be widened by shortening treatment, but limited research means it is unclear which…

Applications · Statistics 2019-11-07 L. McCabe , I. R. White , N. V. Vinh Chau , E. Barnes , S. L. Pett , G. S. Cooke , A. S. Walker

Due to the costliness of labelled data in real-world applications, semi-supervised object detectors, underpinned by pseudo labelling, are appealing. However, handling confusing samples is nontrivial: discarding valuable confusing samples…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Changrui Chen , Kurt Debattista , Jungong Han

We consider the problem of high-dimensional non-linear variable selection for supervised learning. Our approach is based on performing linear selection among exponentially many appropriately defined positive definite kernels that…

Machine Learning · Computer Science 2009-09-08 Francis Bach

Motivation: Genomic data analyses such as Genome-Wide Association Studies (GWAS) or Hi-C studies are often faced with the problem of partitioning chromosomes into successive regions based on a similarity matrix of high-resolution,…

Statistics Theory · Mathematics 2019-02-06 Christophe Ambroise , Alia Dehman , Pierre Neuvial , Guillem Rigaill , Nathalie Vialaneix

Robust estimators for linear regression require non-convex objective functions to shield against adverse affects of outliers. This non-convexity brings challenges, particularly when combined with penalization in high-dimensional settings.…

Computation · Statistics 2025-08-08 David Kepplinger , Siqi Wei

In recent years, data selection has emerged as a core issue for large-scale visual-language model pretraining, especially on noisy web-curated datasets. One widely adopted strategy assigns quality scores such as CLIP similarity for each…

Machine Learning · Computer Science 2024-02-06 Yiping Wang , Yifang Chen , Wendan Yan , Kevin Jamieson , Simon Shaolei Du

Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nisreen Albzour , Sarah S. Lam

When modelling HIV epidemics, it is important to incorporate set-point viral load and its heritability. As set-point viral load distributions can differ significantly amongst epidemics, it is imperative to account for the observed local…

Populations and Evolution · Quantitative Biology 2018-11-28 Pieter Libin , Laurens Hernalsteen , Kristof Theys , Perpetua Gomes , Ana Abecasis , Ann Nowe

The Third-Generation in DNA sequencing has emerged in the last few years using new technologies that allow the production of long-read sequences. Applications of the Third-Generation sequencing enable real-time and on-site data production,…

Populations and Evolution · Quantitative Biology 2019-02-26 Hyunjin Shim

Complex industrial systems are continuously monitored by a large number of heterogeneous sensors. The diversity of their operating conditions and the possible fault types make it impossible to collect enough data for learning all the…

Artificial Intelligence · Computer Science 2019-08-27 Gabriel Michau , Yang Hu , Thomas Palmé , Olga Fink

In this paper, we are concerned with how to select significant variables in semiparametric modeling. Variable selection for semiparametric regression models consists of two components: model selection for nonparametric components and…

Statistics Theory · Mathematics 2008-12-18 Runze Li , Hua Liang

Due to the lack of quality annotation in medical imaging community, semi-supervised learning methods are highly valued in image semantic segmentation tasks. In this paper, an advanced consistency-aware pseudo-label-based self-ensembling…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Ziyang Wang , Tianze Li , Jian-Qing Zheng , Baoru Huang

The fundamental task of classification given a limited number of training data samples is considered for physical systems with known parametric statistical models. The standalone learning-based and statistical model-based classifiers face…

Machine Learning · Computer Science 2022-02-01 Alireza Nooraiepour , Waheed U. Bajwa , Narayan B. Mandayam

Using only global image-class labels, weakly-supervised learning methods, such as class activation mapping, allow training CNNs to jointly classify an image, and locate regions of interest associated with the predicted class. However,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Soufiane Belharbi , Marco Pedersoli , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Competing risk analysis considers event times due to multiple causes, or of more than one event types. Commonly used regression models for such data include 1) cause-specific hazards model, which focuses on modeling one type of event while…

Applications · Statistics 2017-04-27 Jiayi Hou , Anthony Paravati , Ronghui Xu , James Murphy

Automatic segmentation of anatomical structures with convolutional neural networks (CNNs) constitutes a large portion of research in medical image analysis. The majority of CNN-based methods rely on an abundance of labeled data for proper…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Cheryl Sital , Tom Brosch , Dominique Tio , Alexander Raaijmakers , Jürgen Weese

Medical image segmentation aims to identify anatomical structures at the voxel-level. Segmentation accuracy relies on distinguishing voxel differences. Compared to advancements achieved in studies of the inter-class variance, the…

Image and Video Processing · Electrical Eng. & Systems 2025-03-19 Yali Bi , Enyu Che , Yinan Chen , Yuanpeng He , Jingwei Qu
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