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In this paper, we propose a scheme to eliminate the influence of noises on system dynamics, by means of a sequential unsharp measurements and unitary feedback operations. The unsharp measurements are carried out periodically during system…

Quantum Physics · Physics 2018-09-19 Du Ran , Ye-Hong Chen , Zhi-Cheng Shi , Zhen-Biao Yang , Jie Song , Yan Xia

How biological networks achieve robust control despite relying on imperfect, local information remains an important open question. Here, we identify thermodynamic constraints that can curtail non-equilibrium steady-state responses so…

Statistical Mechanics · Physics 2026-05-27 Carlos Floyd , Aaron R. Dinner , Suriyanarayanan Vaikuntanathan

Molecular signalling in living cells occurs at low copy numbers and is thereby inherently limited by the noise imposed by thermal diffusion. The precision at which biochemical receptors can count signalling molecules is intimately related…

Statistical Mechanics · Physics 2016-09-26 Aljaz Godec , Ralf Metzler

We examine the problem of regret minimization when the learner is involved in a continuous game with other optimizing agents: in this case, if all players follow a no-regret algorithm, it is possible to achieve significantly lower regret…

Computer Science and Game Theory · Computer Science 2023-03-20 Yu-Guan Hsieh , Kimon Antonakopoulos , Volkan Cevher , Panayotis Mertikopoulos

We study the correction of errors intervening in two-qubit dissipating into their own environments. This is done by resorting to local feedback actions with the aim of preserving as much as possible the initial amount of entanglement.…

Quantum Physics · Physics 2016-08-30 Morteza Rafiee , Alireza Nourmandipour , Stefano Mancini

Many cellular components are present in such low numbers that individual stochastic production and degradation events lead to significant fluctuations in molecular abundances. Although feedback control can, in principle, suppress such…

Molecular Networks · Quantitative Biology 2025-12-25 Ryan Ripsman , Brayden Kell , Andreas Hilfinger

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

This paper addresses the problem of robust control of a linear discrete-time system subject to bounded disturbances and to measurement and control budget constraints. Using Q-parameterization and a polytope containment method, we prove that…

Optimization and Control · Mathematics 2021-09-23 Antoine Aspeel , Kwesi Rutledge , Raphaël M. Jungers , Benoit Macq , Necmiye Özay

The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products from a single network can act to control their own…

Biological Physics · Physics 2009-11-06 Jeff Hasty , Joel Pradines , Milos Dolnik , J. J. Collins

We derive exact solutions of simplified models for the temporal evolution of the protein concentration within a cell population arbitrarily far from the stationary state. We show that monitoring the dynamics can assist in modeling and…

Biomolecules · Quantitative Biology 2015-05-13 Sandro Azaele , Jayanth R. Banavar , Amos Maritan

From a mathematical point of view self-organization can be described as patterns to which certain dynamical systems modeling social dynamics tend spontaneously to be attracted. In this paper we explore situations beyond self-organization,…

Optimization and Control · Mathematics 2014-03-24 Marco Caponigro , Massimo Fornasier , Benedetto Piccoli , Emmanuel Trélat

We introduce a novel, biologically plausible local learning rule that provably increases the robustness of neural dynamics to noise in nonlinear recurrent neural networks with homogeneous nonlinearities. Our learning rule achieves higher…

Neurons and Cognition · Quantitative Biology 2022-10-12 Christopher H. Stock , Sarah E. Harvey , Samuel A. Ocko , Surya Ganguli

To maintain renewing epithelial tissues in a healthy, homeostatic state, (stem) cell divisions and differentiation need to be tightly regulated. Mechanisms of homeostatic control often rely on crowding control: cells are able to sense the…

Tissues and Organs · Quantitative Biology 2023-01-16 Cristina Parigini , Philip Greulich

We investigate the efficient transmission and processing of weak, subthreshold signals in a realistic neural medium in the presence of different levels of the underlying noise. Assuming Hebbian weights for maximal synaptic conductances --…

Biological Physics · Physics 2015-08-19 Joaquin J. Torres , Irene Elices , J. Marro

Living systems implement and execute an extraordinary plethora of computational tasks. The inherent degree of large scale coordination emerges as a global property, from the intricate sea of microscopic interactions. The brain, with its…

Disordered Systems and Neural Networks · Physics 2018-01-03 Duccio Fanelli , Francesco Ginelli , Roberto Livi , Niccolò Zagli , Clement Zankoc

Why do neurons communicate through spikes? By definition, spikes are all-or-none neural events which occur at continuous times. In other words, spikes are on one side binary, existing or not without further details, and on the other can…

Neurons and Cognition · Quantitative Biology 2024-04-12 Antoine Grimaldi , Amélie Gruel , Camille Besnainou , Jean-Nicolas Jérémie , Jean Martinet , Laurent U Perrinet

We investigate feedback control of the cooperative dynamics of two coupled neural oscillators that is induced merely by external noise. The interacting neurons are modelled as FitzHugh-Nagumo systems with parameter values at which no…

Chaotic Dynamics · Physics 2009-11-11 B. Hauschildt , N. B. Janson , A. Balanov , E. Schoell

How choices are made within noisy environments is a central question in the neuroscience of decision making. Previous work has characterized temporal accumulation of evidence for decision-making in static environments. However, real-world…

Neurons and Cognition · Quantitative Biology 2017-10-18 Alex Piet , Ahmed El Hady , Carlos D Brody

We introduce a quantum control protocol that produces smooth, experimentally implementable control sequences optimized to combat temporally correlated noise for single qubit systems. The control ansatz is specifically chosen to be a…

Quantum Physics · Physics 2023-01-30 Yasuo Oda , Dennis Lucarelli , Kevin Schultz , B. David Clader , Gregory Quiroz

Heavy-tailed stochastic gradient noise, commonly observed in transformer models, can destabilize the optimization process. Recent works mainly focus on developing and understanding approaches to address heavy-tailed noise in the centralized…

Machine Learning · Computer Science 2026-02-23 Junfei Sun , Dixi Yao , Xuchen Gong , Tahseen Rabbani , Manzil Zaheer , Tian Li
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