Probing Noise in Gene Expression and Protein Production
Biomolecules
2015-05-13 v1 Statistical Mechanics
Biological Physics
Abstract
We derive exact solutions of simplified models for the temporal evolution of the protein concentration within a cell population arbitrarily far from the stationary state. We show that monitoring the dynamics can assist in modeling and understanding the nature of the noise and its role in gene expression and protein production. We introduce a new measure, the cell turnover distribution, which can be used to probe the phase of transcription of DNA into messenger RNA.
Cite
@article{arxiv.0902.0941,
title = {Probing Noise in Gene Expression and Protein Production},
author = {Sandro Azaele and Jayanth R. Banavar and Amos Maritan},
journal= {arXiv preprint arXiv:0902.0941},
year = {2015}
}
Comments
10 pages, 3 figures, supplementary information on request