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Complex functional brain networks are large networks of brain regions and functional brain connections. Statistical characterizations of these networks aim to quantify global and local properties of brain activity with a small number of…

Neurons and Cognition · Quantitative Biology 2011-07-19 Mikail Rubinov , Olaf Sporns

Understanding brain connectivity has become one of the most important issues in neuroscience. But connectivity data can reflect either the functional relationships of the brain activities or the anatomical properties between brain areas.…

Neurons and Cognition · Quantitative Biology 2015-04-13 Tiago Simas , Mario Chavez , Pablo Rodriguez , Albert Diaz-Guilera

Multivariate Pattern (MVP) classification holds enormous potential for decoding visual stimuli in the human brain by employing task-based fMRI data sets. There is a wide range of challenges in the MVP techniques, i.e. decreasing noise and…

Machine Learning · Statistics 2016-12-28 Muhammad Yousefnezhad , Daoqiang Zhang

The study of brain differences across Eastern and Western populations provides vital insights for understanding potential cultural and genetic influences on cognition and mental health. Diffusion MRI (dMRI) tractography is an important tool…

Brain regions are often topographically connected: nearby locations within one brain area connect with nearby locations in another area. Mapping these connection topographies, or 'connectopies' in short, is crucial for understanding how…

Quantitative Methods · Quantitative Biology 2017-07-18 Koen V. Haak , Andre F. Marquand , Christian F. Beckmann

We propose a novel and efficient algorithm to model high-level topological structures of neuronal fibers. Tractography constructs complex neuronal fibers in three dimensions that exhibit the geometry of white matter pathways in the brain.…

Computer Vision and Pattern Recognition · Computer Science 2021-08-04 S. Shailja , Angela Zhang , B. S. Manjunath

Most approaches to the estimation of brain functional connectivity from the functional magnetic resonance imaging (fMRI) data rely on computing some measure of statistical dependence, or more generally, a distance between univariate…

Computer Vision and Pattern Recognition · Computer Science 2022-09-26 Oleg Kachan , Alexander Bernstein

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield

In this work, we propose a novel framework to encode the local connectivity patterns of brain, using Fisher Vectors (FV), Vector of Locally Aggregated Descriptors (VLAD) and Bag-of-Words (BoW) methods. We first obtain local descriptors,…

Computer Vision and Pattern Recognition · Computer Science 2016-10-18 Itir Onal Ertugrul , Mete Ozay , Fatos T. Yarman Vural

We present the concept of fiber-flux density for locally quantifying white matter (WM) fiber bundles. By combining scalar diffusivity measures (e.g., fractional anisotropy) with fiber-flux measurements, we define new local descriptors…

Computer Vision and Pattern Recognition · Computer Science 2017-09-20 Itay Benou , Ronel Veksler , Alon Friedman , Tammy Riklin Raviv

The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

Computer Vision and Pattern Recognition · Computer Science 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

Diffusion Tensor Imaging (DTI) is a non-invasive imaging technique that allows estimation of the location of white matter tracts in-vivo, based on the measurement of water diffusion properties. For each voxel, a second-order tensor can be…

Computer Vision and Pattern Recognition · Computer Science 2013-10-24 Miriam H. A. Bauer , Sebastiano Barbieri , Jan Klein , Jan Egger , Daniela Kuhnt , Bernd Freisleben , Horst K. Hahn , Christopher Nimsky

Lesion-symptom mapping studies provide insight into what areas of the brain are involved in different aspects of cognition. This is commonly done via behavioral testing in patients with a naturally occurring brain injury or lesions (e.g.,…

Functional Magnetic Resonance Imaging (fMRI) maps cerebral activation in response to stimuli but this activation is often difficult to detect, especially in low-signal contexts and single-subject studies. Accurate activation detection can…

Applications · Statistics 2023-10-26 Wei-Chen Chen , Ranjan Maitra

High angular resolution diffusion imaging data is the observed characteristic function for the local diffusion of water molecules in tissue. This data is used to infer structural information in brain imaging. Nonparametric scalar measures…

Applications · Statistics 2011-08-17 Sofia C. Olhede , Brandon Whitcher

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Parcellation of white matter tractography provides anatomical features for disease prediction, anatomical tract segmentation, surgical brain mapping, and non-imaging phenotype classifications. However, parcellation does not always reach…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Yui Lo , Yuqian Chen , Fan Zhang , Dongnan Liu , Leo Zekelman , Suheyla Cetin-Karayumak , Yogesh Rathi , Weidong Cai , Lauren J. O'Donnell

White matter hyperintensities (WMH) are bright regions on T2-weighted magnetic resonance imaging (MRI) scans and are associated with cerebrovascular pathology and neurodegeneration, including myelin loss. While Luxol Fast Blue…

Tractography fiber clustering using diffusion MRI (dMRI) is a crucial strategy for white matter (WM) parcellation. Current methods primarily use the geometric information of fibers (i.e., the spatial trajectories) to group similar fibers…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Jin Wang , Bocheng Guo , Yijie Li , Junyi Wang , Yuqian Chen , Jarrett Rushmore , Nikos Makris , Yogesh Rathi , Lauren J O'Donnell , Fan Zhang

Diffusion Tensor Imaging (DTI) allows estimating the position, orientation and dimension of bundles of nerve pathways. This non-invasive imaging technique takes advantage of the diffusion of water molecules and determines the diffusion…

Computer Vision and Pattern Recognition · Computer Science 2011-03-09 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky