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Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern…

Machine Learning · Statistics 2015-04-03 Emanuele Olivetti , Thien Bao Nguyen , Paolo Avesani

The surface Boundary Element Method (BEM) is one of the most commonly employed formulations to solve the forward problem in electroencephalography, but the applicability of its classical incarnations is lamentably limited to piece-wise…

Image and Video Processing · Electrical Eng. & Systems 2020-04-27 Maxime Y. Monin , Lyes Rahmouni , Francesco P. Andriulli

3D-Polarized Light Imaging (3D-PLI) is a neuroimaging technique used to study the structural connectivity of the human brain at the meso- and microscale. In 3D-PLI, the complex nerve fiber architecture of the brain is characterized by 3D…

Computational Physics · Physics 2020-12-21 Felix Matuschke , Kévin Ginsburger , Cyril Poupon , Katrin Amunts , Markus Axer

White matter hyperintensity (WMH) is commonly found in elder individuals and appears to be associated with brain diseases. U-net is a convolutional network that has been widely used for biomedical image segmentation. Recently, U-net has…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Yue Zhang , Wanli Chen , Yifan Chen , Xiaoying Tang

Diffusion Weighted Imaging (DWI) is an advanced imaging technique commonly used in neuroscience and neurological clinical research through a Diffusion Tensor Imaging (DTI) model. Volumetric scalar metrics including fractional anisotropy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Zihao Tang , Xinyi Wang , Lihaowen Zhu , Mariano Cabezas , Dongnan Liu , Michael Barnett , Weidong Cai , Chengyu Wang

To the best of our knowledge, all existing methods that can generate synthetic brain magnetic resonance imaging (MRI) scans for a specific individual require detailed structural or volumetric information about the individual's brain.…

Neurons and Cognition · Quantitative Biology 2025-04-25 Ruijie Wang , Luca Rossetto , Susan Mérillat , Christina Röcke , Mike Martin , Abraham Bernstein

To understand biological intelligence we need to map neuronal networks in vertebrate brains. Mapping mesoscale neural circuitry is done using injections of tracers that label groups of neurons whose axons project to different brain regions.…

Neurons and Cognition · Quantitative Biology 2025-05-13 Samik Banerjee , Caleb Stam , Daniel J. Tward , Steven Savoia , Yusu Wang , Partha P. Mitra

Conventional viscoelastic characterization of brain white matter (BWM), typically described using Prony series models, remains a largely empirical representation that is difficult to interpret physically. Growing evidence suggests that…

Medical Physics · Physics 2026-01-28 P. Pasupathy , J. G. Georgiadis , A. A Pelegri

Diffusion tensor imaging (DTI) is a widely used method for studying brain white matter development and degeneration. However, standard DTI estimation methods depend on a large number of high-quality measurements. This would require long…

Image and Video Processing · Electrical Eng. & Systems 2022-11-16 Davood Karimi , Ali Gholipour

Axons in white matter have been shown to have varying geometries within a bundle using ex vivo imaging techniques, but what does this mean for diffusion MRI (dMRI) based spherical deconvolution (SD)? SD attempts to estimate the fibre…

Medical Physics · Physics 2022-03-04 Ross Callaghan , Daniel C. Alexander , Marco Palombo , Hui Zhang

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Autism spectrum disorder (ASD) is a complex neurodevelopmental syndrome. Early diagnosis and precise treatment are essential for ASD patients. Although researchers have built many analytical models, there has been limited progress in…

Neurons and Cognition · Quantitative Biology 2018-10-30 Juntang Zhuang , Nicha C. Dvornek , Xiaoxiao Li , Pamela Ventola , James S. Duncan

This paper explores uncertainty quantification (UQ) as an indicator of the trustworthiness of automated deep-learning (DL) tools in the context of white matter lesion (WML) segmentation from magnetic resonance imaging (MRI) scans of…

We present a novel method for characterizing the microstructure of a material from volumetric datasets such as 3D image data from computed tomography (CT). The method is based on a new statistical model for the distribution of voxel…

Materials Science · Physics 2021-01-06 Elise Otterlei Brenne , Vedrana Andersen Dahl , Peter Stanley Jørgensen

Functional connections in the brain are frequently represented by weighted networks, with nodes representing locations in the brain, and edges representing the strength of connectivity between these locations. One challenge in analyzing…

Applications · Statistics 2022-09-28 Yura Kim , Daniel Kessler , Elizaveta Levina

Recent advances in neuroimaging have enabled studies in functional connectivity (FC) of human brain, alongside investigation of the neuronal basis of cognition. One important FC study is the representation of vision in human brain. The…

Neurons and Cognition · Quantitative Biology 2025-10-29 Debanjali Bhattacharya , Neelam Sinha

Image Quality of MRI brain scans is strongly influenced by within scanner head movements and the resulting image artifacts alter derived measures like brain volume and cortical thickness. Automated image quality assessment is key to…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Felix Hoffstaedter , Nicolás Nieto , Simon B. Eickhoff , Kaustubh R. Patil

Historically, functional magnetic resonance imaging (fMRI) of the brain has focused primarily on gray matter, particularly the cortical gray matter and associated nuclei. However, recent work has demonstrated that functional activity in…

Medical Physics · Physics 2025-07-10 Zhiyuan Li , Kurt G. Schilling , Bennett A. Landman

Diffusion Magnetic Resonance Imaging (dMRI) is a non-invasive tool for watching the microstructure of fibrous nerve and muscle tissue. From dMRI, it is possible to estimate 2-rank diffusion tensors imaging (DTI) fields, that are widely used…

Computer Vision and Pattern Recognition · Computer Science 2016-06-28 Hernan Dario Vargas Cardona , Mauricio A. Alvarez , Alvaro A. Orozco
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