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The bacterial flagellar motor is a highly efficient rotary machine used by many bacteria to propel themselves. It has recently been shown that at low speeds its rotation proceeds in steps [Sowa et al. (2005) Nature 437, 916--919]. Here we…

Biological Physics · Physics 2009-10-25 Thierry Mora , Howard Yu , Yoshiyuki Sowa , Ned S. Wingreen

The phase behavior of hydrocarbon fluids confined in porous media has been reported to deviate significantly from that in the bulk environment due to the existence of sub-10nm pores. Though experiments and simulations have measured the…

Soft Condensed Matter · Physics 2020-03-16 Jiaoyan Li , Qi Rao , Yidong Xia , Michael P. Hoepfner , Milind Deo

Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how…

Dispersal is essential to the plethora of motile microorganisms living in porous environments, yet how it relates to movement patterns and pore space structure remains largely unknown. Here we investigate numerically the long-time dispersal…

Soft Condensed Matter · Physics 2025-03-06 T. Pietrangeli , R. Foffi , R. Stocker , C. Ybert , C. Cottin-Bizonne , F. Detcheverry

We experimentally investigate how aerotactic bacteria, confined within a thin liquid film between two solid substrates, respond to a controlled oxygen gradient. We find that the total bacterial number density dictates which mechanism…

Soft Condensed Matter · Physics 2026-04-07 Minjun Kim , Joonwoo Jeong

Gas bubble transport through highly porous transport layers (PTLs) is a key process in electrochemical devices such as proton exchange membrane water electrolyzers, where bubbles generated at catalyst surfaces must migrate through complex…

Soft Condensed Matter · Physics 2026-03-31 J. M. P. Beunen , T. Lappan , P. Malgaretti , O. Aouane , K. Eckert , J. Harting

Culturing cells confined in microscale geometries has been reported in many studies this last decade, in particular following the development of microfluidic-based applications and lab-on-a-chip devices. Such studies usually examine growth…

Diffusive transport of small molecules within the internal structures of biological and synthetic material systems is complex because the crowded environment presents chemical and physical barriers to mobility. We explored this mobility…

Soft Condensed Matter · Physics 2020-09-29 Rajarshi Guha , Subhadip Ghosh , Darrell Velegol , Peter J. Butler , Ayusman Sen , Jennifer L. Ross

Elastic confinements are an important component of many biological systems and dictate the transport properties of suspended particles under flow. In this chapter, we review the Brownian motion of a particle moving in the vicinity of a…

Soft Condensed Matter · Physics 2022-10-28 Abdallah Daddi-Moussa-Ider , Stephan Gekle

The motion of a eukaryotic cell presents a variety of interesting and challenging problems from both a modeling and a computational perspective. The processes span many spatial scales (from molecular to tissue) as well as disparate time…

Cell Behavior · Quantitative Biology 2010-11-25 Ben Vanderlei , James J. Feng , Leah Edelstein-Keshet

Activity can organize matter in unique configurations inaccessible to equilibrium systems, including a sundry of spiraling shapes seen in nature that range from galaxies to living tissues to fossilized stromatolites. How these dynamic yet…

Soft Condensed Matter · Physics 2023-05-23 Xingting Gong , Manu Prakash

Cell crawling crucially depends on the collective dynamics of the acto-myosin cytoskeleton. However, it remains an open question to what extent cell polarization and persistent motion depend on continuous regulatory mechanisms and…

Biological Physics · Physics 2023-08-11 Fenna Stegemerten , Karin John , Uwe Thiele

Adhesion-independent migration is a prominent mode of cell motility in confined environments, yet the physical principles that guide such movement remain incompletely understood. We present a phase-field model for simulating the motility of…

In this letter, we show that pore-scale diffusiophoresis of colloidal particles along local salt gradients manifests in the macroscopic dispersion of particles in a porous medium. Despite is transient character, this microscopic phenomenon…

Soft Condensed Matter · Physics 2023-03-16 Mamta Jotkar , Pietro de Anna , Marco Dentz , Luis Cueto-Felgueroso

A thin-walled tube, e.g., a drinking straw, manifests an instability when bent by localizing the curvature change in a small region. This instability has been extensively studied since the seminal work of Brazier nearly a century ago.…

Soft Condensed Matter · Physics 2022-02-03 Luyi Qiu , John W. Hutchinson , Ariel Amir

Some euglenids, a family of aquatic unicellular organisms, can develop highly concerted, large-amplitude peristaltic body deformations. This remarkable behaviour has been known for centuries. Yet, its function remains controversial, and is…

Soft Condensed Matter · Physics 2020-05-26 Giovanni Noselli , Alfred Beran , Marino Arroyo , Antonio DeSimone

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

Dynamical Systems · Mathematics 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

Proliferation is a defining feature of life. Through growth, division, and death, living systems consume energy and inject mass, breaking conservation laws and driving collective phenomena from biofilm formation to embryonic development.…

Statistical Mechanics · Physics 2026-03-25 Nicola Pellicciotta , Luca Angelani , Roberto Di Leonardo

Many types of bacteria swim by rotating a bundle of helical filaments also called flagella. Each filament is driven by a rotary motor and a very flexible hook transmits the motor torque to the filament. We model it by discretizing…

Biological Physics · Physics 2012-01-04 Reinhard Vogel , Holger Stark

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn