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Consider a multiple hypothesis testing setting involving rare/weak effects: relatively few tests, out of possibly many, deviate from their null hypothesis behavior. Summarizing the significance of each test by a P-value, we construct a…

Statistics Theory · Mathematics 2021-10-20 David L. Donoho , Alon Kipnis

A flourishing empirical literature investigates the prevalence of $p$-hacking based on the distribution of $p$-values across studies. Interpreting results in this literature requires a careful understanding of the power of methods for…

Econometrics · Economics 2025-08-12 Graham Elliott , Nikolay Kudrin , Kaspar Wüthrich

Equivalence testing is of emerging importance in genomics studies but has hitherto been little studied in this content. In this paper, we define the notion of equivalence of gene expression and determine a `strength of evidence' measure for…

Applications · Statistics 2012-02-03 J. Tuke , G. F. V. Glonek , P. J. Solomon

Let $(X,Y)$ be a random variable consisting of an observed feature vector $X\in \mathcal{X}$ and an unobserved class label $Y\in \{1,2,...,L\}$ with unknown joint distribution. In addition, let $\mathcal{D}$ be a training data set…

Statistics Theory · Mathematics 2008-06-26 Lutz Duembgen , Bernd-Wolfgang Igl , Axel Munk

Much research on Machine Learning testing relies on empirical studies that evaluate and show their potential. However, in this context empirical results are sensitive to a number of parameters that can adversely impact the results of the…

Software Engineering · Computer Science 2023-09-12 Salah Ghamizi , Maxime Cordy , Yuejun Guo , Mike Papadakis , And Yves Le Traon

Based on the work of Romano and Shaikh (2006) and Lehmann and Romano (2005) we give a sufficient criterion for controlling generalised error rates for arbitrarily dependent p-values. This criterion is formulated in terms of matrices…

Methodology · Statistics 2016-12-16 Sebastian Döhler

There is a well-known problem in Null Hypothesis Significance Testing: many statistically significant results fail to replicate in subsequent experiments. We show that this problem arises because standard `point-form null' significance…

Methodology · Statistics 2025-02-06 Fintan Costello , Paul Watts

$P$-values have been the focus of considerable criticism based on various considerations. Still, the $P$-value represents one of the most commonly used statistical tools. When assessing the suitability of a single hypothesized distribution,…

Statistics Theory · Mathematics 2010-01-13 Michael Evans , Gun Ho Jang

Assigning significance in high-dimensional regression is challenging. Most computationally efficient selection algorithms cannot guard against inclusion of noise variables. Asymptotically valid p-values are not available. An exception is a…

Methodology · Statistics 2009-06-12 Nicolai Meinshausen , Lukas Meier , Peter Bühlmann

Consistently checking the statistical significance of experimental results is the first mandatory step towards reproducible science. This paper presents a hitchhiker's guide to rigorous comparisons of reinforcement learning algorithms.…

Methodology · Statistics 2022-08-30 Cédric Colas , Olivier Sigaud , Pierre-Yves Oudeyer

Bayesian hypothesis testing via Bayes factors offers a principled alternative to classical p-value methods in meta-analysis, particularly suited to its cumulative and sequential nature. Unlike commonly reported p-values for standard null…

Methodology · Statistics 2026-04-22 Joris Mulder , Robbie C. M. van Aert

Statistical significance measures the reliability of a result obtained from a random experiment. We investigate the number of repetitions needed for a statistical result to have a certain significance. In the first step, we consider…

Methodology · Statistics 2024-06-19 Maike Tormählen , Galiya Klinkova , Michael Grabinski

Models are consistently treated as approximations and all procedures are consistent with this. They do not treat the model as being true. In this context $p$-values are one measure of approximation, a small $p$-value indicating a poor…

Other Statistics · Statistics 2016-11-21 Laurie Davies

We introduce probability estimation, a broadly applicable framework to certify randomness in a finite sequence of measurement results without assuming that these results are independent and identically distributed. Probability estimation…

Quantum Physics · Physics 2018-11-30 Yanbao Zhang , Emanuel Knill , Peter Bierhorst

The controversy about statistical significance vs. scientific relevance is more than 100 years old. But still nowadays null hypothesis significance testing is considered as gold standard in many empirical fields from economics and social…

Applications · Statistics 2022-11-23 Uwe Hassler

The classical theory for the meta-analysis of $p$-values is based on the assumption that if the overall null hypothesis is true, then all $p$-values used in a chosen combined test statistic are genuine, i.e., are observations from…

Computation · Statistics 2024-10-08 Rui Santos , M. Fátima Brilhante , Sandra Mendonça

In this paper we use e-values in the context of multiple hypothesis testing assuming that the base tests produce independent, or sequential, e-values. Our simulation and empirical studies and theoretical considerations suggest that, under…

Methodology · Statistics 2024-08-14 Vladimir Vovk , Ruodu Wang

This paper studies the construction of p-values for nonparametric outlier detection, taking a multiple-testing perspective. The goal is to test whether new independent samples belong to the same distribution as a reference data set or are…

Methodology · Statistics 2024-03-12 Stephen Bates , Emmanuel Candès , Lihua Lei , Yaniv Romano , Matteo Sesia

Particle physics experiments such as those run in the Large Hadron Collider result in huge quantities of data, which are boiled down to a few numbers from which it is hoped that a signal will be detected. We discuss a simple probability…

Applications · Statistics 2011-02-18 A. C. Davison , N. Sartori

The study of associations and their causal explanations is a central research activity whose methodology varies tremendously across fields. Even within specialized subfields, comparisons across textbooks and journals reveals that the basics…

Methodology · Statistics 2025-10-13 Sander Greenland
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