Related papers: Capture and light-induced release of antibiotics b…
Antimicrobial resistance (AMR) poses a global health threat, reducing the effectiveness of antibiotics and complicating clinical decision-making. To address this challenge, we introduce abx_amr_simulator, a Python-based simulation package…
We use moving light patterns to control the motion of {\it Escherichia coli} bacteria whose motility is photo-activated. Varying the pattern speed controls the magnitude and direction of the bacterial flux, and therefore the accumulation of…
Antimicrobial photodynamic therapy (aPDT) is a promising modality for inactivation of antibiotic resistant bacteria, relying on the activation of a photosensitizer (PS) by light of a specific wavelength. This process results in the…
Antibiotic resistance is a topical problem for both humans and animals and has been the subject of special monitoring for two decades. Several recent studies, including ours, have shown that this phenomenon is accentuated by the transfer of…
A new light responsive arylazopyrazole (AAP) containing polymer matrix thin film is fabricated by spin-coating of different concentrations of the AAP azo dye into the polydimethylsiloxane (PDMS) polymer at 150C. The new AAP molecular switch…
Heteropolymer gels can be engineered to release specific molecules into or absorb molecules from a surrounding solution. This remarkable ability is the basis for developing gel applications in extensive areas such as drug delivery, waste…
The subject of analysis is a non-linear three-compartment model, widely used in pharmacological absorption studies. It has been transformed into a general form, thus leading automatically to an appropriate approximation. This made the…
New combinations of existing antibiotics are being investigated to combat bacterial resilience. This requires detection technologies with reasonable cost, accuracy, resolution, and throughput. Here, we present a multi -drug screening…
Light-activated drugs are a promising way to treat localized diseases for which existing treatments have severe side effects. However, their development is complicated by the set of photophysical and biological properties that must be…
Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with correct antibiotics and slowing down the emergence of antibiotic-resistant bacteria. Here, we report a phenotypic platform that rapidly…
We use amplified spontaneous emission (ASE) and linear absorption spectroscopy to study the mechanisms of reversible photodegradation of 1-amino-2-methylanthraquinone (disperse orange 11-DO11) in solid poly(methyl methacrylate).…
The mechanism of reversible photodegradation of 1-substituted aminoanthraquinones doped into poly(methyl methacrylate) and polystyrene is investigated. Time-dependent density functional theory is employed to predict the transition energies…
In this work, we use a double-layered stack of TiO2 nanotubes (TiNTs) to construct a visible-light triggered drug delivery system. Key for visible-light drug release is a hydrophobic cap on the nanotubes containing Au nanoparticles (AuNPs).…
Surfaces formed by extracellular polymeric substances enclosing individual and some small communities of {\it Acidithiobacillus ferrooxidans} on plates of hydrophobic silicon and hydrophilic mica are analyzed by means of atomic force…
Raman spectroscopy is a promising tool for microbial identification, yet its implementation in microbiology and clinical workflow is still restricted due to the accompanying additional preparation required to focus on microbial signals.…
Adsorption of dimers is modelled using random sequential adsorption algorithm. The interaction between molecules is given by screened electrostatic potential. The paper focuses on the properties of adsorbed monolayers as well as the…
FoF1-ATP synthases are membrane-embedded protein machines that catalyze the synthesis of adenosine triphosphate. Using photoactivation-based localization microscopy (PALM) in TIR-illumination as well as structured illumination microscopy…
Diffusion of colored dye on water saturated paper substrates has been traditionally exploited with great skill by renowned water color artists. The same physics finds more recent practical applications in paper based diagnostic devices…
Damped Lyman-alpha systems (DLAs) seen in the spectra of high-z QSOs allow us to probe the physical conditions in protogalaxies. Our understanding of physical conditions in DLAs at high-z is primarily based on the absorption lines of H_2…
De novo therapeutic design is challenged by a vast chemical repertoire and multiple constraints, e.g., high broad-spectrum potency and low toxicity. We propose CLaSS (Controlled Latent attribute Space Sampling) - an efficient computational…